Cited by 53Phytochemicals and Antioxidant ActivitiesAntioxidant Activity and Oxidative StressEdible Oils Quality and Analysis

Carotenoids in fresh and processed tomato (Solanum lycopersicum) fruits protect cells from oxidative stress injury

Del Giudice, Rita, Petruk, Ganna, Raiola, Assunta, Barone, Amalia, Monti, Daria Maria, Rigano, Maria Manuela·2017·Journal of the Science of Food and Agriculture

Abstract

BACKGROUND: Lipophilic antioxidants in tomato (Solanum lycopersicum) fruits exert important functions in reducing the risk of human diseases. Here the effect of thermal processing on the antioxidant activity of lipophilic extracts from the commercial tomato hybrid ‘Zebrino’ was analysed. Carotenoid content and lipophilic antioxidant activity were determined and the ability of tomato extracts in rescuing cells from oxidative stress was assessed. RESULTS: Lipophilic antioxidant activity was completely retained after heat treatment and extracts were able to mitigate the detrimental effect induced by oxidative stress on different cell lines. Lycopene alone was able to rescue cells from oxidative stress, even if to a lower extent compared with tomato extracts. These results were probably due to the synergistic effect of tomato compounds in protecting cells from oxidative stress injury. CONCLUSION: The current study provides valuable insights into the health effect of the dietary carotenoids present in fresh and processed tomato fruits. © 2016 Society of Chemical Industry

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Crossref · 10.1002/jsfa.7910

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37 of 37 references verified0 citation errors · 0 not checkable

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  • Tomato extracts rich in lycopene are effective in counteracting detrimental effects induced by oxidative stress caused by sodium arsenite on different human cell lines.

    “We recently demonstrated that tomato extracts, rich in lycopene, are effective in counteracting the detrimental effects induced by oxidative stress caused by treatments with sodium arsenite on different human cell lines [80].”

    From Antioxidants from Plants Protect against Skin Photoaging (2018) · cites this paper as [80]

  • Carotenoids extracted from fresh and processed tomato fruits showed cytoprotective activity, mitigated ROS production induced by oxidative stress, and prevented GSH depletion and lipid peroxidation.

    “In particular, we found that carotenoids extracted from both fresh and processed tomato fruits showed cytoprotective activity, were able to mitigate ROS production induced by oxidative stress, and prevented GSH depletion and lipid peroxidation [80].”

    From Antioxidants from Plants Protect against Skin Photoaging (2018) · cites this paper as [80]

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Authors
Del Giudice, R., Petruk, G., Raiola, A., Barone, A., Monti, D. M., & Rigano, M. M.
Affiliations
  • Department of Chemical Sciences, University of Naples Federico II Complesso Universitario Monte Sant'Angelo Via Cinthia 4 I‐80126 Naples Italy
  • University of Naples Federico II (IT)
Corresponding author
  • Monti, Daria Maria
  • Rigano, Maria Manuela
Venue
Journal of the Science of Food and Agriculture
Publisher
Wiley
Published
2016-08-18
Volume
97
Issue
5
Pages
1616-1623
ISSN
  • 0022-5142 (ISSN-L)
  • 1097-0010
OpenAlex
W2501500029
Cited by
53
References
37
Citations by year
2026: 3 · 2025: 3 · 2024: 5 · 2023: 3 · 2022: 5 · 2021: 7 · 2020: 9 · 2019: 4 · 2018: 9 · 2017: 5
FWCI
4.71
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of the Science of Food and Agriculture (publishedVersion)
  • PubMed (publishedVersion)
Funders
GenoPOM-pro (PON02_00395_3082360)
Topics
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
  • Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Keywords
tomato, carotenoids, lycopene, oxidative stress, lipophilic antioxidants, thermal processing, heat treatment (food and biological processing), tomato extract, synergistic antioxidant effect, cytoprotection, dietary carotenoids
MeSH terms
Lycopene, Animals, Antioxidants, Carotenoids, Food Handling, Fruit, Humans, Plant Extracts, Oxidative Stress, Solanum lycopersicum, Cell Line, Tumor, Rats

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