The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
The Biopsied Donor Liver: Incorporating Macrosteatosis Into High-Risk Donor Assessment
Open accessAbstract
To expand the donor liver pool, ways are sought to better define the limits of marginally transplantable organs. The Donor Risk Index (DRI) lists 7 donor characteristics, together with cold ischemia time and location of the donor, as risk factors for graft failure. We hypothesized that donor hepatic steatosis is an additional independent risk factor. We analyzed the Scientific Registry of Transplant Recipients for all adult liver transplants performed from October 1, 2003, through February 6, 2008, with grafts from deceased donors to identify donor characteristics and procurement logistics parameters predictive of decreased graft survival. A proportional hazard model of donor variables, including percent steatosis from higher-risk donors, was created with graft survival as the primary outcome. Of 21,777 transplants, 5051 donors had percent macrovesicular steatosis recorded on donor liver biopsy. Compared to the 16,726 donors with no recorded liver biopsy, the donors with biopsied livers had a higher DRI, were older and more obese, and a higher percentage died from anoxia or stroke than from head trauma. The donors whose livers were biopsied became our study group. Factors most strongly associated with graft failure at 1 year after transplantation with livers from this high-risk donor group were donor age, donor liver macrovesicular steatosis, cold ischemia time, and donation after cardiac death status. In conclusion, in a high-risk donor group, macrovesicular steatosis is an independent risk factor for graft survival, along with other factors of the DRI including donor age, donor race, donation after cardiac death status, and cold ischemia time. Liver Transpl 16:874–884, 2010. © 2010 AASLD.
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Cites
A Model to Predict Survival in Patients With End–Stage Liver Disease
Kamath, P. S., Wiesner, R. H., Malinchoc, M., Kremers, W., Therneau, T. M., Kosberg, C. L., D'Amico, G., Dickson, R. E., & Kim, R. W. (2001) · Hepatology · doi:10.1053/jhep.2001.22172 · Cited by 4,975
Characteristics Associated with Liver Graft Failure: The Concept of a Donor Risk Index
Feng, S., Goodrich, N. P., Bragg-Gresham, J. L., Dykstra, D. M., Punch, J. D., DebRoy, M. A., Greenstein, S. M., & Merion, R. M. (2006) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2006.01242.x · Cited by 1,958
RISK FACTORS FOR PRIMARY DYSFUNCTION AFTER LIVER TRANSPLANTATION—A MULTIVARIATE ANALYSIS
PLOEG, R. J., DʼALESSANDRO, A. M., KNECHTLE, S. J., STEGALL, M. D., PIRSCH, J. D., HOFFMANN, R. M., SASAKI, T., SOLLINGER, H. W., BELZER, F. O., & KALAYOGLU, M. (1993) · Transplantation · doi:10.1097/00007890-199304000-00024 · Cited by 1,026
The Survival Benefit of Liver Transplantation
Merion, R. M., Schaubel, D. E., Dykstra, D. M., Freeman, R. B., Port, F. K., & Wolfe, R. A. (2005) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2004.00703.x · Cited by 872
A model to predict survival in patients with end-stage liver disease
Kamath, P. S., Wiesner, R. H., Malinchoc, M., Kremers, W. K., Therneau, T. M., D'Amico, G., Kosberg, C. L., Dickson, E. R., & Kim, W. R. (2001) · Gastroenterology · doi:10.1016/s0016-5085(08)80377-0 · Cited by 615
Characteristics Associated with Liver Graft Failure: The Concept of a Donor Risk Index
Fenga, S. (2006) · Cited by 364
Burroughs, A. K., Sabin, C. A., Rolles, K., Delvart, V., Karam, V., Buckels, J., O'Grady, J. G., Castaing, D., Klempnauer, J., Jamieson, N., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68033-1 · Cited by 333
Halldorson, J. B., Bakthavatsalam, R., Fix, O., Reyes, J. D., & Perkins, J. D. (2009) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2008.02491.x · Cited by 318
Self-citationAssessment of Hepatic Steatosis by Expert Pathologists: The End of a Gold Standard
El-Badry, A. M., Breitenstein, S., Jochum, W., Washington, K., Paradis, V., Rubbia-Brandt, L., Puhan, M. A., Slankamenac, K., Graf, R., & Clavien, P.-A. (2009) · Annals of Surgery · doi:10.1097/sla.0b013e3181bcd6dd · Cited by 307
Desai, N. M., Mange, K. C., Crawford, M. D., Abt, P. L., Frank, A. M., Markmann, J. W., Velidedeoglu, E., Chapman, W. C., & Markmann, J. F. (2004) · Transplantation · doi:10.1097/01.tp.0000101009.91516.fc · Cited by 264
Cited by
The Eurotransplant Donor Risk Index in Liver Transplantation: ET-DRI
Braat, A. E., Blok, J. J., Putter, H., Adam, R., Burroughs, A. K., Rahmel, A. O., Porte, R. J., Rogiers, X., & Ringers, J. (2012) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2012.04195.x · Cited by 305
Challenges to Liver Transplantation and Strategies to Improve Outcomes
Dutkowski, P., Linecker, M., DeOliveira, M. L., Müllhaupt, B., & Clavien, P.-A. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.08.045 · Cited by 270
Kim, D.-S., Yoon, Y.-I., Kim, B. K., Choudhury, A., Kulkarni, A., Park, J. Y., Kim, J., Sinn, D. H., Joo, D. J., Choi, Y., et al. (2024) · Hepatology International · doi:10.1007/s12072-023-10629-3 · Cited by 47
Metadata
- Authors
- Spitzer, A. L., Lao, O. B., Dick, A. A. S., Bakthavatsalam, R., Halldorson, J. B., Yeh, M. M., Upton, M. P., Reyes, J. D., & Perkins, J. D.
- Venue
- Liver Transplantation
- Published
- 2010-07
- Volume
- 16
- Issue
- 7
- Pages
- 874-884
- ISSN
- 1527-6465 (ISSN-L)
- OpenAlex
- W2063820248
- Cited by
- 342
- References
- 27
- FWCI
- 12.11
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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