The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
D-MELD, a Simple Predictor of Post Liver Transplant Mortality for Optimization of Donor/Recipient Matching
Open accessAbstract
Numerous donor and recipient risk factors interact to influence the probability of survival after liver transplantation. We developed a statistic, D-MELD, the product of donor age and preoperative MELD, calculated from laboratory values. Using the UNOS STAR national transplant data base, we analyzed survival for first liver transplant recipients with chronic liver failure from deceased after brain death donors. Preoperative D-MELD score effectively stratified posttransplant survival. Using a cutoff D-MELD score of 1600, we defined a subgroup of donor-recipient matches with significantly poorer short- and long-term outcomes as measured by survival and length of stay (LOS). Avoidance of D-MELD scores above 1600 improved results for subgroups of high-risk patients with donor age >/=60 and those with preoperative MELD >/=30. D-MELD >/=1600 accurately predicted worse outcome in recipients with and without hepatitis C. There is significant regional variation in average D-MELD scores at transplant, however, regions with larger numbers of high D-MELD matches do not have higher survival rates. D-MELD is a simple, highly predictive tool for estimating outcomes after liver transplantation. This statistic could assist surgeons and their patients in making organ acceptance decisions. Applying D-MELD to liver allocation could eliminate many donor/recipient matches likely to have inferior outcome.
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A Model to Predict Survival in Patients With End–Stage Liver Disease
Kamath, P. S., Wiesner, R. H., Malinchoc, M., Kremers, W., Therneau, T. M., Kosberg, C. L., D'Amico, G., Dickson, R. E., & Kim, R. W. (2001) · Hepatology · doi:10.1053/jhep.2001.22172 · Cited by 4,975
Model for end-stage liver disease (MELD) and allocation of donor livers
Wiesner, R., Edwards, E., Freeman, R., Harper, A., Kim, R., Kamath, P., Kremers, W., Lake, J., Howard, T., Merion, R. M., et al. (2003) · Gastroenterology · doi:10.1053/gast.2003.50016 · Cited by 2,528
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Characteristics Associated with Liver Graft Failure: The Concept of a Donor Risk Index
Feng, S., Goodrich, N. P., Bragg-Gresham, J. L., Dykstra, D. M., Punch, J. D., DebRoy, M. A., Greenstein, S. M., & Merion, R. M. (2006) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2006.01242.x · Cited by 1,958
The Survival Benefit of Liver Transplantation
Merion, R. M., Schaubel, D. E., Dykstra, D. M., Freeman, R. B., Port, F. K., & Wolfe, R. A. (2005) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2004.00703.x · Cited by 872
The utility of marginal donors in liver transplantation
Busuttil, R. W., & Tanaka, K. (2003) · Liver Transplantation · doi:10.1053/jlts.2003.50105 · Cited by 662
Heuman, D. M., Abou-Assi, S. G., Habib, A., Williams, L. M., Stravitz, T. R., Sanyal, A. J., Fisher, R. A., & Mihas, A. A. (2004) · Hepatology · doi:10.1002/hep.1840400409 · Cited by 546
Duffy, J. P., Vardanian, A., Benjamin, E., Watson, M., Farmer, D. G., Ghobrial, R. M., Lipshutz, G., Yersiz, H., Lu, D. S. K., Lassman, C., et al. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e318148c704 · Cited by 445
Prospective validation of the Barcelona Clinic Liver Cancer staging system
Cillo, U., Vitale, A., Grigoletto, F., Farinati, F., Brolese, A., Zanus, G., Neri, D., Boccagni, P., Srsen, N., D'Amico, F., et al. (2006) · Journal of Hepatology · doi:10.1016/j.jhep.2005.12.015 · Cited by 425
Cited by
The Biopsied Donor Liver: Incorporating Macrosteatosis Into High-Risk Donor Assessment
Spitzer, A. L., Lao, O. B., Dick, A. A. S., Bakthavatsalam, R., Halldorson, J. B., Yeh, M. M., Upton, M. P., Reyes, J. D., & Perkins, J. D. (2010) · Liver Transplantation · doi:10.1002/lt.22085 · Cited by 342
Self-citationChallenges to Liver Transplantation and Strategies to Improve Outcomes
Dutkowski, P., Linecker, M., DeOliveira, M. L., Müllhaupt, B., & Clavien, P.-A. (2015) · Gastroenterology · doi:10.1053/j.gastro.2014.08.045 · Cited by 270
Briceño, J., Cruz-Ramírez, M., Prieto, M., Navasa, M., Ortiz de Urbina, J., Orti, R., Gómez-Bravo, M.-Á., Otero, A., Varo, E., Tomé, S., et al. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.05.039 · Cited by 152
Metadata
- Authors
- Halldorson, J. B., Bakthavatsalam, R., Fix, O., Reyes, J. D., & Perkins, J. D.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 9
- Issue
- 2
- Pages
- 318-326
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W1989852995
- Cited by
- 318
- References
- 30
- FWCI
- 9.70
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- CoChat. (2026). Citation check: D-MELD, a Simple Predictor of Post Liver Transplant Mortality for Optimization of Donor/Recipient Matching. https://app.cochat.ai/papers/10.1111/j.1600-6143.2008.02491.x
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- Halldorson, J. B., Bakthavatsalam, R., Fix, O., Reyes, J. D., & Perkins, J. D. (2009). D-MELD, a Simple Predictor of Post Liver Transplant Mortality for Optimization of Donor/Recipient Matching. American Journal of Transplantation. https://doi.org/10.1111/j.1600-6143.2008.02491.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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