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Reactive Oxygen Species (ROS) Responsive Polymers for Biomedical Applications
Open accessAbstract
Reactive oxygen species (ROS) play important roles in cell signaling pathways, while increased production of ROS may disrupt cellular homeostasis, giving rise to oxidative stress and a series of diseases. Utilizing these cell‐generated species as triggers for selective tuning polymer structures and properties represents a promising methodology for disease diagnosis and treatment. Recently, significant progress has been made in fabricating biomaterials including nanoparticles and macroscopic networks to interact with this dynamic physiological condition. These ROS‐responsive platforms have shown potential in a range of biomedical applications, such as cancer targeted drug delivery systems, cell therapy platforms for inflammation related disease, and so on. image
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Cites
Hydrogen peroxide in the human body
Halliwell, B., Clement, M. V., & Long, L. H. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)02197-9 · Cited by 1,075
ROS signaling and redox biology in endothelial cells
Panieri, E., & Santoro, M. M. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1928-9 · Cited by 168
Cited by
Moradi Kashkooli, F., Soltani, M., & Souri, M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.08.012 · Cited by 514
Overcoming the translational barriers of tissue adhesives
Taboada, G. M., Yang, K., Pereira, M. J. N., Liu, S. S., Hu, Y., Karp, J. M., Artzi, N., & Lee, Y. (2020) · Nature Reviews Materials · doi:10.1038/s41578-019-0171-7 · Cited by 449
Selenium‐Doped Carbon Quantum Dots for Free‐Radical Scavenging
Li, F., Li, T., Sun, C., Xia, J., Jiao, Y., & Xu, H. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201705989 · Cited by 409
Stimuli-Responsive Polymer-Based Nanosystems for Cancer Theranostics
Wei, D., Sun, Y., Zhu, H., & Fu, Q. (2023) · ACS Nano · doi:10.1021/acsnano.3c06019 · Cited by 303
He, X., Wang, X., Yang, L., Yang, Z., Yu, W., Wang, Y., Liu, R., Chen, M., & Gao, H. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.02.001 · Cited by 89
Metadata
- Authors
- Xu, Q., He, C., Xiao, C., & Chen, X.
- Venue
- Macromolecular Bioscience
- Publisher
- Wiley
- Published
- 2016-02-18
- Volume
- 16
- Issue
- 5
- Pages
- 635-646
- ISSN
- 1616-5187 (ISSN-L)
- 1616-5195
- OpenAlex
- W2280162925
- Cited by
- 364
- References
- 2
- FWCI
- 15.46
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Xu, Q., He, C., Xiao, C., & Chen, X. (2016). Reactive Oxygen Species (ROS) Responsive Polymers for Biomedical Applications. Macromolecular Bioscience. https://doi.org/10.1002/mabi.201500440
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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