The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Peptidomics: Identification and quantification of endogenous peptides in neuroendocrine tissues
Abstract
Neuropeptides perform a large variety of functions as intercellular signaling molecules. While most proteomic studies involve digestion of the proteins with trypsin or other proteases, peptidomics studies usually analyze the native peptide forms. Neuropeptides can be studied by using mass spectrometry for identification and quantitation. In many cases, mass spectrometry provides an understanding of the precise molecular form of the native peptide, including post‐translational cleavages and other modifications. Quantitative peptidomics studies generally use differential isotopic tags to label two sets of extracted peptides, as done with proteomic studies, except that the Cys‐based reagents typically used for quantitation of proteins are not suitable because most peptides lack Cys residues. Instead, a number of amine‐specific labels have been created and some of these are useful for peptide quantitation by mass spectrometry. In this review, peptidomics techniques are discussed along with the major findings of many recent studies and future directions for the field. © 2006 Wiley Periodicals, Inc. Mass Spec Rev 25:327–344, 2006
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Ghrelin is a growth-hormone-releasing acylated peptide from stomach
Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H., & Kangawa, K. (1999) · Nature · doi:10.1038/45230 · Cited by 8,479
Ong, S.-E., Blagoev, B., Kratchmarova, I., Kristensen, D. B., Steen, H., Pandey, A., & Mann, M. (2002) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m200025-mcp200 · Cited by 5,574
Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R. M., Tanaka, H., Williams, S. C., Richardson, J. A., Kozlowski, G. P., Wilson, S., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)80949-6 · Cited by 5,501
New insights into copper monooxygenases and peptide amidation: Structure, mechanism and function
Prigge, S. T., Mains, R. E., Eipper, B. A., & Amzel* **, L. M. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000763 · Cited by 460
Metabolic Labeling of Mammalian Organisms with Stable Isotopes for Quantitative Proteomic Analysis
Wu, C. C., MacCoss, M. J., Howell, K. E., Matthews, D. E., & Yates, J. R. (2004) · Analytical Chemistry · doi:10.1021/ac049208j · Cited by 386
Protein identification using sequential ion/ion reactions and tandem mass spectrometry
Coon, J. J., Ueberheide, B., Syka, J. E. P., Dryhurst, D. D., Ausio, J., Shabanowitz, J., & Hunt, D. F. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503189102 · Cited by 373
Cited by
Shilov, I. V., Seymour, S. L., Patel, A. A., Loboda, A., Tang, W. H., Keating, S. P., Hunter, C. L., Nuwaysir, L. M., & Schaeffer, D. A. (2007) · Molecular & Cellular Proteomics · doi:10.1074/mcp.t600050-mcp200 · Cited by 1,298
Kuehnbaum, N. L., & Britz-McKibbin, P. (2013) · Chemical Reviews · doi:10.1021/cr300484s · Cited by 354
Fricker, L. D. (2020) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010919-023603 · Cited by 309
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Metadata
- Authors
- Fricker, L. D., Lim, J., Pan, H., & Che, F.
- Venue
- Mass Spectrometry Reviews
- Publisher
- Wiley
- Published
- 2006-01-10
- Volume
- 25
- Issue
- 2
- Pages
- 327-344
- ISSN
- 0277-7037 (ISSN-L)
- 1098-2787
- OpenAlex
- W1996238403
- Cited by
- 212
- References
- 6
- FWCI
- 7.25
- Type
- journal article
- Language
- en
- Open access
- closed
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