Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications

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Items 201–300 of 441

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4. The Roles of Protein S -Palmitoylation in Cancers: From Dynamic Modulation to Therapeutic Potential
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5. The Role of Protein Post-Translational Modifications in the Pathogenesis of Nephrolithiasis: Mechanistic Insights and Translational Potential
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6. Protein modification systems as cancer biomarkers and therapeutic targets
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7. From mechanisms to therapies: exploiting epigenetic and post-translational modifications of mitochondrial quality control in diabetic kidney disease
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8. Processing and release of endogenous immunogenic peptide signals
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10. Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification
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11. Crosstalk between lactylation and other post-translational modifications in health and diseases
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12. ST6GAL1-mediated sialyl linkage switching drives cancer-promoting α2,6-sialo-protrusions radiating from anti-inflammatory TAMs
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13. Functional and Extracellular Production and Antitumor Activity of Mouse Alpha Klotho in Model Microalga Chlamydomonas reinhardtii
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15. Protein Modifications During Early Embryo Development
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17. Post-translational modifications as a key mechanism for herpes simplex virus type I evasion of host innate immunity
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18. Recombinant Proteins: Evolution to their Therapeutic Potential
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19. A Novel Gene Signature Associated with Protein Post-translational Modification to Predict Clinical Outcomes and Therapeutic Responses of Colorectal Cancer
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20. Novel Heterocyclic PAD4 Inhibitors for Treating Diseases
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21. gNR4Aly Link Bridging Cellular Metabolism, Lactylation, and Vascular Calcification
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22. ST6GAL1-mediated sialyl linkage switching in tumor-associated macrophages drives cancer-promoting nanotubes carrying α2,6-sialylation in anti-inflammatory cells
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32. Pharmacological Targeting of DHHC9 ‐Mediated STRN4 Palmitoylation to Suppress YAP ‐Driven Cancer Metastasis
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37. Glutamine Substitution at Lysine 609 in the Autoinhibitory Region Modulates Catalysis, Uncoupling, and Conformational Dynamics of Endothelial Nitric Oxide Synthase
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39. USP39 inhibits MLKL phosphorylation and deubiquitination to suppress necroptosis of nucleus pulposus cells and attenuate intervertebral disc degeneration
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40. A Systematic Approach to Selecting the Right Tool for Mass Spectrometry Data Analysis in Protein and Peptide Bioanalysis
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41. Altered AADAC Modulates Trophoblast Invasion and Suggests a Potential Angiogenic Regulatory Role in Severe Preeclampsia
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42. Caspase Recruitment Domain Family Member 8: A Favorable Target in the Pathogenesis of Atherosclerosis
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43. Post-translational modifications of triosephosphate isomerase reveal metabolic vulnerabilities in T-ALL: effect of combining dichloroacetic acid and the PPI rabeprazole
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44. Lysine malonylation regulates human sperm motility
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52. Protein succinylation in disease: Mechanistic insights and therapeutic targeting
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56. Oxidation‐Induced C‐Terminal Amidation Marks Proteins for Degradation
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57. Cross-talk between glycosylation pathways: Mechanistic insights and implications for human diseases
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58. TRIM21-mediated ubiquitination of PARP1 regulated by the PI3K/AKT-STAT5A axis suppresses small cell lung cancer
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73. Functional Production, Extracellular Expression, and Antitumor Activity of Mouse Alpha-Klotho in Model Microalga Chlamydomonas reinhardtii
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76. Serial enrichment-based quantitative proteomics enables deep and multiplexed profiling of post-translational modifications
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