Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications

Cited by (441)

Items 401–441 of 441

1. TaHL-PTM: Post-Translational Modification Prediction in Proteins via Target-Hooked Discriminative Fine-Tuning of Decoder-only Protein Language Models
   Bhawana Prasain, Pawel Pratyush, Stefan Schulze, Dukka B. KC · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
2. Chemically Induced Proximity in Biological Modulation
   Xiaokang Jin, Chen Zhou, Xiaoyu Zhang · 2026 · ACS Bio & Med Chem Au
3. Protein Fragments: From Biomarkers to Therapeutic Targets—A Focus on α1‐Antitrypsin‐Derived Peptides
   Friedemann Börner, Tomasz Iwanicki, Julia Held, Joanna Chorostowska‐Wynimko, Aleksandra Jezela‐Stanek, Sabina M Janciauskiene · 2026 · Mediators of Inflammation
4. Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
   Yuxing Yao, Jinxiu Qian, Qiqiong Liu, Wanting Ye, Ying Xing, Xiuyun Bai, Rongjun Deng, Jue Yang, Cheng Lu, Cheng Xiao et al. · 2026 · MedComm
5. Nonhistone Protein Acetylation Reprograms the ECM-Receptor Interaction Pathway: Multiomics Profiling of Cartilage Degeneration in Rat Models of Osteoarthritis
   Jiahao Sun, Teng Ma, Qi Sun, Xu Cui, Ximin Jin, Yongkui Zhang, Wenpeng Xie · 2026 · Journal of Proteome Research
6. Post-translational protein S-palmitoylation in renal tubular injury: mechanisms and therapeutic implications
   Miao Li, Han Zhu, Huiping Zhao, Chenyang Liu, Yan Wang, Li Zuo · 2026 · Frontiers in Cell and Developmental Biology
7. Assay for In-Vitro Arginine Methylation of RNA Binding Proteins Followed by RNA Binding
   Sakshi Dewasthale, Gayatri Mohanan, Purusharth I Rajyaguru · 2026 · Methods in molecular biology
8. Protein Post‐Translational Modifications in UV ‐Induced Skin Damage
   Yuanyuan Xu, Chong Zhang, Tianyi Zhang, Yan Yan, Baoxi Wang · 2026 · Experimental Dermatology
9. Multi-omics based biomarkers in acute coronary syndrome: Towards precision in cardiovascular medicine
   Yash Paul Sharma, Deven Mittal, Kraticka Singhal, Naveena N, Juniali Hatwal, Akshyaya Kumar Pradhan, Ashish Singh, Bishav Mohan, Akash Batta · 2026 · Indian Heart Journal
10. IGF-1Eb Isoform Immunoreactivity May Be Associated with Placental Dysfunction and Vascular Pathology in Fetal Growth Restriction (FGR)
    Apostolos Fasoulopoulos, Michail N. Varras, Fani‐Niki Varra, Viktoria‐Konstantina Varra, Αnastassios Philippou, Alexandros Gryparis, Αrgyro Papadopetraki, Petros Stellatos, Athina Pesiridou, Kleopatra Paparizou et al. · 2026 · Biomolecules
11. MALDI-Based Multiomics and Spatial Molecular Profiling—Principles, Integrated Workflows, Biomedical Applications, and Future Perspectives: A Systematic Review
    D. Bartusik-Aebisher, Izabella Wilk, B. George, D. Aebisher · 2026 · Biophysica
12. Post-translational modifications in Neuroimmune cells during neuroinflammation: integrated regulatory networks and therapeutic opportunities
    Wei Li, Yaqi Liu, Haoling Zhang, Haolong Zhang, Wenwen Shao, Ting Hu, Yan Liao, Wangzheqi Zhang, Xiaohong Kang · 2026 · Biology Direct
13. Molecular context of pathogenic variants is associated with phenotype and treatment response in SCN8A-related disorders
    Joshua Hack, Joseph C. Watkins, Michael F. Hammer · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
14. Chemical basis for arginine citrullination by human PAD4
    Nurgül Bilgin, Laust Moesgaard, Jacob Kongsted, Jasmin Mecinović · 2026 · Chemical Communications
15. PhoSARte: identification of SARS-CoV-2 phosphorylation sites using contrastive learning and protein language models
    Nhat Truong Pham, Duong Thanh Tran, Qiaosen Su, Yeona Jung, Nattanong Bupi, Dahyun Kang, Sukchan Lee, Balachandran Manavalan · 2026 · Briefings in Bioinformatics
16. HMGB1 Post-Translational Modifications in Epstein–Barr Virus-Associated Nasopharyngeal Carcinoma: Current Evidence, Emerging Mechanistic Concepts, and Unresolved Questions
    Cho Yiu Lau, Khadija Shahed Khan, Dora L.�W. Kwong, Wei Dai, Ngar‐Woon Kam · 2026 · International Journal of Molecular Sciences
17. Single-molecule protein sequencing: One step closer to the ultimate performance of protein biomarker assays
    Yiqi Ruben Luo, Liwei Zheng, Seong‐Ho Shin · 2026 · Advances in clinical chemistry
18. Structural biology approaches in neurodegeneration and aging
    Minhal Abidi, Sana Iram, Jamal‐E‐Fatima, Hamda Khan, Shaheda Perween, Safia Habib, Moinuddin · 2026 · Elsevier eBooks
19. Integrating structural and omics data for drug discovery
    Neha, Khushi Raza · 2026 · Elsevier eBooks
20. Machine Learning-Driven Surface-Enhanced Raman Spectroscopy (SERS) Profiling of Low Molecular Weight Serum from Cervical Cancer Patients
    Shama Sehar, Maria Ghafoor, Muhammad Zeeshan Majeed, Haq Nawaz, Nosheen Rashid, Hafiza Elbadie Ahmed, Muhammad Zeeshan Majeed, Allah Ditta, Muhammad Zain Ul Abideen, Asmat Ullah et al. · 2026 · Analytical Letters
21. Advances in Biomarker Discovery for Cardiovascular Disease
    Qin Fu, Haijun Liu · 2026 · Biomedicines
22. SCRMP-mediated SUMOylation of CSNK2B facilitates DNA damage repair to promote cisplatin resistance in small cell lung cancer
    Yuli Chen, Qinnan Chen, Jiahao Guo, Ziwei Li, Shaokun Yu, Peng Huang, Ke Xiao, Xuefei Shi, Ming Sun, 聂凤琪 et al. · 2026 · Science Translational Medicine
23. PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma
    Fen Xue, Dingkong Liang, Xin Chen, Fei Fan, Xiayun He · 2026 · Advanced Science
24. Discovery of Post‐Translationally Modified Epitopes in Autoimmunity: Someone Has to Fish so Everyone Can Eat
    Sanya Arshad, Benjamin M. Cameron, Alok V. Joglekar · 2026 · Immunological Reviews
25. Calmodulin: The Essential Biological Regulator Self-Regulates Its Activity, Structure and Function
    Danton H. O’Day · 2026 · Biology
26. Disease-specific glycosylation in the neurodegenerative brain
    Meredith Edwards, Natasha Vassileff, Joern R Steinert, Jereme G. Spiers · 2026 · Elsevier eBooks
27. ISG15 Is a Key Multidirectional Regulator of Cytosolic RNA- and DNA-Sensing Pathways and Type I Interferon Feedback Loops
    Maleana Khoury, Sergey Iordanskiy · 2026 · International Journal of Molecular Sciences
28. ER-Nε-lysine acetylation machinery in neurological disorders: A context-dependent regulator of proteostasis
    Emanuele Di Martino, Raanya De Vos, Sofia Koenig Gimeno, Federica Ricciardi, Antonio Luchicchi, Nicola Salvatore Orefice · 2026 · Current Opinion in Chemical Biology
29. Comparative Analysis of Altered lncRNA and mRNA Expression Profiles in RMI1-Knockdown Cells Following Ionizing Radiation Exposure
    Mengmeng Yang, Xin Wang, Na Lu, Jiale Li, Dengfeng Zhang, Huanteng Zhang, Jiebing Guan, Yidan Zhang, Yidan Wang, Shoukai Li et al. · 2026 · Dose-Response
30. Enzyme−Targeted Therapeutics for Neurological Disorders
    Leonardo Massignan, Kanduru Lokesh, Sara Ziadat, David Uehling, Donald Fredric Weaver, Mark A. Reed · 2026 · Journal of Medicinal Chemistry
31. Mechanisms of phosphorylation in colitis regulation: PP2Acα as an emerging therapeutic target for inflammatory bowel disease
    Guanghao Wu, Chuan Wang, Chao Fang, Jun Li · 2026 · Molecular Biology Reports
32. Targeting post-translational modifications to overcome glioblastoma therapy resistance: emerging strategies and natural compounds
    Tetsade Piermartiri, Ana Carolini Adriana da Matta, João Victor Krüger Pinto, Carla I. Tasca, Cláudia Beatriz Nedel · 2026 · Frontiers in Oncology
33. Oxidative Stress, Post‐Translational Modifications, and Type 1 Diabetes Pathogenesis
    Colleen J. Winstead, Miki Hodel, Hubert Ming Tse · 2026 · Immunological Reviews
34. Nanopore Sequencing for Epigenetic Decoding: Applications, Analytical Constraints, and Translational Prospects
    Jiachao Xin, Jiaxuan Liu, Yichao Liu, Xinru Liu, Mengke Ma, An Huang, Zijie Ye, Pengfan Zhang, Xue Wang, Tao Zeng et al. · 2026 · International Journal of Molecular Sciences
35. Thalamic PDK–PDHA1 Signaling is Associated with Opioid-Induced Loss-of-Righting-Reflex Sensitivity: Evidence from Phosphoproteomic Profiling and PDK Pathway Intervention
    Man Li, Yijia Zhang, Bo Tan, Ruibin Su · 2026 · Neurochemical Research
36. Exploring protein glycosylation across GlyGen, UniProtKB, and related knowledgebases for data integration
    Jeet Kiran Vora, Kate Warner, Preethi Vasudev, Sandra E. Orchard, Sujeet Kulkarni, Raja Mazumder, Maria Jesus Martin · 2026 · Database
37. The PHLPP paradox revisited: from canonical AKT phosphatases to signaling pseudoenzymes in human disease
    Esraa M. Shaaban, Moemena F. Elnaggar, Asmaa Abdelgawad, mohamed sedeek, Shady Estfanos, Omar Eladl · 2026 · Biochemical Pharmacology
38. Data processing in proteomics and metabolomics: liquid chromatography–mass spectrometry-based omics with divergent computational paradigms
    Amy Zheng, Bin Liao, Liang N. Zhang, Tao Huan · 2026 · Briefings in Bioinformatics
39. Protein palmitoylation in disease: decoding its crosstalk with ubiquitination and phosphorylation for pathogenic mechanisms and targeted therapeutics
    Sainan Li, Huanjin Suo, Renqiang Hao, Ruohan Wu, Yinming Liang, Eryan Kong, Liu Cao, Binhui Zhou · 2026 · Journal of genetics and genomics/Journal of Genetics and Genomics
40. Stress hyperglycemia impairs FOXK2-dependent macrophage cardiac repair after myocardial infarction
    Huizhen Lv, Zening Liu, Suli Feng, Wennan Liu, Yifan Guo, Kaiwen Bao, Xilin Shen, Yongle Li, Xin Zhou, Ding Ai et al. · 2026 · Cell Reports
41. Fungal ADP-ribosylation: an emerging signalling pathway in adaptation and virulence
    Johanna Mary Martha Gosciniak, J.G.M. Rack · 2026 · Biochemical Society Transactions