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Cited by 340

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Higher incidence of depression preceding the onset of Parkinson's disease: A register study

Leentjens, Albert F.G., Van den Akker, Marjan, Metsemakers, Job F.M., Lousberg, Richel, Verhey, Frans R.J.·2003·Movement Disorders
DOI 10.1002/mds.10387
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Abstract

Although case histories of depression preceding Parkinson's disease (PD) point to a possible pathophysiological relationship between these two disorders, there is as yet no epidemiological evidence to support this view. We compared the incidence of depression in patients later diagnosed with PD with that of a matched control population. Using data from an ongoing general practice‐based register study, the lifetime incidence of depressive disorder was calculated for patients until their diagnosis of PD and compared with that of a matched control population from the same register. At the time of analysis, the register held information on 105,416 people. At the time of their diagnosis of PD, 9.2% of the patients had a history of depression, compared with 4.0% of the control population (χ 2 = 22.388, df = 1, P < 0.001). The odds ratio for a history of depression for these patients was 2.4 (95% CI: 2.1–2.7). We concluded that the higher incidence of depression in patients who were later diagnosed with PD supports the hypothesis of there being a biological risk factor for depression in these patients. © 2003 Movement Disorder Society

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Metadata

Authors
Leentjens, A. F. G., Van den Akker, M., Metsemakers, J. F. M., Lousberg, R., & Verhey, F. R. J.
Venue
Movement Disorders
Publisher
Wiley
Published
2003-01-24
Volume
18
Issue
4
Pages
414-418
ISSN
  • 0885-3185 (ISSN-L)
  • 1531-8257
DOI
10.1002/mds.10387
OpenAlex
W1968726432
Cited by
340
References
28
FWCI
6.01
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Higher incidence of depression preceding the onset of Parkinson's disease: A register study. https://app.cochat.ai/papers/10.1002/mds.10387
The paper
Leentjens, A. F. G., Van den Akker, M., Metsemakers, J. F. M., Lousberg, R., & Verhey, F. R. J. (2003). Higher incidence of depression preceding the onset of Parkinson's disease: A register study. Movement Disorders. https://doi.org/10.1002/mds.10387

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.