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Cited by 275

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Increased risk of Parkinson’s disease after depression: A retrospective cohort study

Schuurman, A. G., van den Akker, M., Ensinck, K. T.J.L., Metsemakers, J. F.M., Knottnerus, J. A., Leentjens, A. F.G., Buntinx, F.·2002·Neurology

Abstract

BACKGROUND: Depression has been linked to the occurrence of a number of somatic diseases. There are no data for PD. OBJECTIVE: To determine if depression is associated with a subsequent risk for PD. METHODS: A retrospective cohort study design based in general practice was applied. All subjects diagnosed with depression between 1975 and 1990 were included and matched with subjects with the same birth year who were never diagnosed with depression. Follow-up ended at April 30, 2000. Hazard ratios (HR) and 95% CI were calculated using Cox proportional hazards models adjusted for age, sex, and socioeconomic status. Subgroups based on sex and age at diagnosis of depression were evaluated separately. RESULTS: Among the 1,358 depressed subjects, 19 developed PD, and among the 67,570 nondepressed subjects, 259 developed PD. The HR (95% CI) for depressed vs nondepressed subjects was 3.13 (1.95 to 5.01) in multivariable analysis. Associations in subgroups were comparable with the overall association. CONCLUSION: A strong positive association was found between depression and subsequent incidence of D.

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Metadata

Authors
Schuurman, A. G., van den Akker, M., Ensinck, K. T. J. L., Metsemakers, J. F. M., Knottnerus, J. A., Leentjens, A. F. G., & Buntinx, F.
Venue
Neurology
Published
2002-05-28
Volume
58
Issue
10
Pages
1501-1504
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2047857041
Cited by
275
References
23
FWCI
5.65
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Increased risk of Parkinson’s disease after depression: A retrospective cohort study. https://app.cochat.ai/papers/10.1212/wnl.58.10.1501
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Schuurman, A. G., van den Akker, M., Ensinck, K. T. J. L., Metsemakers, J. F. M., Knottnerus, J. A., Leentjens, A. F. G., & Buntinx, F. (2002). Increased risk of Parkinson’s disease after depression: A retrospective cohort study. Neurology. https://doi.org/10.1212/wnl.58.10.1501

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.