Manic episode with psychotic symptoms induced by subthalamic nucleus stimulation in a patient with Parkinson’s disease.
Open accessAbstract
Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an established therapy for Parkinson's disease (PD). A manic episode with psychotic symptoms induced by STN-DBS occurred in a previously psychiatrically healthy patient, focusing on the role of STN-DBS in influencing not only motor but also emotional behaviour.
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Interaction with world targets can be seen in people who suddenly have their mesolimbic dopamine systems artificially activated for the first time, such as by a newly-implanted brain stimulation electrode.
“interaction with world targets can also be seen in people who suddenly have their mesolimbic dopamine systems artificially activated for the first time, such as by a newly-implanted brain stimulation electrode.”
From Evolving Concepts of Emotion and Motivation (2018) · cites this paper as Herzog et al., 2003
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- Authors
- Herzog, J., Reiff, J., Krack, P., Witt, K., Schrader, B., Müller, D., & Deuschl, G.
- Affiliations
- Christian-Albrechts-Universität zu Kiel (DE)
- Universität Hamburg (DE)
- Corresponding author
- Deuschl, Günther
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2003-07-08
- Volume
- 18
- Issue
- 11
- Pages
- 1382-1384
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W1982557385
- Cited by
- 163
- References
- 14
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 4 · 2022: 4 · 2021: 6 · 2020: 6 · 2019: 9 · 2018: 5 · 2017: 3 · 2016: 8 · 2015: 10 · 2014: 8 · 2013: 16 · 2012: 10
- FWCI
- 4.09
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Movement Disorders (publishedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (publishedVersion, other-oa)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Topics
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Keywords
- subthalamic nucleus, deep brain stimulation, Parkinson's disease, manic episodes, psychosis, emotional behavior, psychiatric adverse effects
- MeSH terms
- Aged, Bipolar Disorder, Electric Stimulation, Female, Humans, Parkinson Disease, Psychotic Disorders, Severity of Illness Index, Subthalamic Nucleus
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