The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Comorbidity of the nonmotor symptoms of Parkinson's disease
Abstract
Many patients with Parkinson's disease (PD) have clinically significant anxiety, depression, fatigue, sleep disturbance, or sensory symptoms. The comorbidity of these nonmotor symptoms and their relationship to PD severity has not been extensively evaluated. Ninety‐ nine nondemented PD patients were evaluated with the following battery of tests: Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Fatigue Severity Scale (FSS), Pittsburgh Sleep Quality Index (PSQI), a sensory symptom questionnaire, Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn & Yahr (H/Y) Stage, and the Schwab & England ADL scale (S/E). The comorbidity of the nonmotor symptoms and their relationship to PD severity was analyzed. Thirty‐six percent of the study population had depression (BDI ≥10), 33% had anxiety (BAI ≥10), 40% had fatigue (FSS > 4), 47% had sleep disturbance (PSQI > 5), and 63% reported sensory symptoms. Only 12% of the sample had no nonmotor symptoms. Fifty‐nine percent of the patients had two or more nonmotor symptoms, and nearly 25% had four or more. Increased comorbidity was associated with greater PD severity (P < 001). This study reveals that the nonmotor symptoms of PD frequently occur together in the same patients. Increased comorbidity of the five nonmotor symptoms was associated with greater PD severity. These results suggest that recognition of these diverse nonmotor symptoms may be enhanced by looking for others when one nonmotor symptom has been identified. © 2001 Movement Disorder Society.
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Cites
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Cited by
Barone, P., Antonini, A., Colosimo, C., Marconi, R., Morgante, L., Avarello, T. P., Bottacchi, E., Cannas, A., Ceravolo, G., Ceravolo, R., et al. (2009) · Movement Disorders · doi:10.1002/mds.22643 · Cited by 1,445
A systematic review of prevalence studies of depression in Parkinson's disease
Reijnders, J. S. A. M., Ehrt, U., Weber, W. E. J., Aarsland, D., & Leentjens, A. F. G. (2008) · Movement Disorders · doi:10.1002/mds.21803 · Cited by 1,239
Non-recognition of depression and other non-motor symptoms in Parkinson's disease
Shulman, L. M., Taback, R. L., Rabinstein, A. A., & Weiner, W. J. (2002) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(01)00015-3 · Cited by 695
Self-citationEffect of Psychiatric and Other Nonmotor Symptoms on Disability in Parkinson's Disease
Weintraub, D., Moberg, P. J., Duda, J. E., Katz, I. R., & Stern, M. B. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52219.x · Cited by 381
Burn, D. J. (2002) · Movement Disorders · doi:10.1002/mds.10114 · Cited by 223
Metadata
- Authors
- Shulman, L. M., Taback, R. L., Bean, J., & Weiner, W. J.
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2001-05
- Volume
- 16
- Issue
- 3
- Pages
- 507-510
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W2042661317
- Cited by
- 417
- References
- 29
- FWCI
- 7.08
- Type
- journal article
- Language
- en
- Open access
- closed
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