The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mood changes and “on‐off” phenomena in Parkinson's disease
Abstract
Ten patients with idiopathic Parkinson's disease and motor fluctuations were rated for mood changes during discrete “off,” “on,” and “on with dyskinesia” periods. The Profile of Mood States and visual analogue scales were used. Significant changes in mood and anxiety were found to parallel changes in motor fluctuations. One patient rated his moods as consistently improving from the “off” state to the “on” state and finally to the “on with dyskinesia” state, a finding that is consistent with concomitant central dopaminergic changes. All other patients showed moods that improved significantly from the “off” state to the “on” state but then worsened significantly in the “on with dyskinesia” state, a finding that is consistent with the fact that patients feel worse when impaired by dyskinesias. It is suggested that these results argue for multiple etiologies of depression in Parkinson's disease. The literature on dopamine and depression in Parkinson's disease is briefly reviewed and the opportunity provided by “on‐off” phenomena to study the effect of dopamine on mood changes is discussed.
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Cites
The use of analogue scales in rating subjective feelings
BOND, A., & LADER, M. (1974) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1974.tb02285.x · Cited by 1,972
Dopamine and depression: A review of recent evidence. I. Empirical studies
Willner, P. (1983) · Brain Research Reviews · doi:10.1016/0165-0173(83)90005-x · Cited by 273
Brown, R. G., Marsden, C. D., Quinn, N., & Wyke, M. A. (1984) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.47.5.454 · Cited by 140
Cited by
Nonmotor fluctuations in Parkinson’s disease: Frequent and disabling
Witjas, T., Kaphan, E., Azulay, J. P., Blin, O., Ceccaldi, M., Pouget, J., Poncet, M., & Chérif, A. A. (2002) · Neurology · doi:10.1212/wnl.59.3.408 · Cited by 642
Quality of life in Parkinson's disease: the relative importance of the symptoms
Rahman, S., Griffin, H. J., Quinn, N. P., & Jahanshahi, M. (2008) · Movement Disorders · doi:10.1002/mds.21667 · Cited by 532
Dopamine Dysregulation Syndrome: An Overview of its Epidemiology, Mechanisms and Management
OʼSullivan, S. S., Evans, A. H., & Lees, A. J. (2009) · CNS Drugs · doi:10.2165/00023210-200923020-00005 · Cited by 265
Anxiety in Parkinson’s disease: A critical review of experimental and clinical studies
Prediger, R. D. S., Matheus, F. C., Schwarzbold, M. L., Lima, M. M. S., & Vital, M. A. B. F. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.039 · Cited by 190
Generalized anxiety disorder and the Hamilton anxiety rating scale in Parkinson's disease
Kummer, A., Cardoso, F., & Teixeira, A. L. (2010) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2010000400005 · Cited by 103
Metadata
- Authors
- Menza, M. A., Sage, J., Marshall, E., Cody, R., & Duvoisin, R.
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 1990-01
- Volume
- 5
- Issue
- 2
- Pages
- 148-151
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- OpenAlex
- W1979605250
- Cited by
- 174
- References
- 3
- FWCI
- 2.50
- Type
- journal article
- Language
- en
- Open access
- closed
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- Menza, M. A., Sage, J., Marshall, E., Cody, R., & Duvoisin, R. (1990). Mood changes and “on‐off” phenomena in Parkinson's disease. Movement Disorders. https://doi.org/10.1002/mds.870050210
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