The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.
A Model for Magnetization Transfer in Tissues
Abstract
Magnetization transfer in several tissues is measured and successfully modeled using a two‐pool model of exchange. The line shape for the semi‐solid pool is characterized by a superLorentzian and the liquid pool by a Lorentzian. The tissues investigated were white and gray matter, optic nerve, muscle, and liver. All tissues the authors studied are characterized by the same model but differ in the parameter values of the model. Blood and cerebral spinal fluid (CSF) were also investigated. The two‐pool model with a Lorentzian line shape for both the semi‐solid and liquid pools modeled the magnetization transfer in blood. In CSF, as expected, there is no measurable exchange of magnetization. The T 2B associated with the semi‐solid pool was short (˜10 μ) for all tissues indicating a fairly rigid semi‐solid pool. In addition characterization of the line shape as superLorentzian indicates molecules such as integral membrane proteins or lipids in membranes are likely molecules participating in the exchange. Conversely, in blood large globular proteins are indicated due to the Lorentzian nature of the semi‐solid pool and a T 2B ≈ 300 μs.
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Cites
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Study of Moderately Rapid Chemical Exchange Reactions by Means of Nuclear Magnetic Double Resonance
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Self-citationMagnetization Transfer and T2 Relaxation Components in Tissue
Harrison, R., Bronskill, M. J., & Henkelman, R. M. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910330406 · Cited by 140
Pulsed saturation transfer contrast
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Cited by
Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI
Sled, J. G., & Pike, G. B. (2001) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1278 · Cited by 419
Insights into brain microstructure from the T2 distribution
MacKay, A., Laule, C., Vavasour, I., Bjarnason, T., Kolind, S., & Mädler, B. (2006) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2005.12.037 · Cited by 347
Zaiss, M., & Bachert, P. (2013) · Physics in Medicine and Biology · doi:10.1088/0031-9155/58/22/r221 · Cited by 323
Jin, T., Wang, P., Zong, X., & Kim, S. (2013) · Magnetic Resonance in Medicine · doi:10.1002/mrm.24315 · Cited by 273
Carlier, P. G., Marty, B., Scheidegger, O., Loureiro de Sousa, P., Baudin, P.-Y., Snezhko, E., & Vlodavets, D. (2016) · Journal of Neuromuscular Diseases · doi:10.3233/jnd-160145 · Cited by 186
Metadata
- Authors
- Morrison, C., & Mark Henkelman, R.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 1995-04
- Volume
- 33
- Issue
- 4
- Pages
- 475-482
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2130735928
- Cited by
- 305
- References
- 15
- FWCI
- 12.74
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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