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Cited by 305

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

A Model for Magnetization Transfer in Tissues

Morrison, Clare, Mark Henkelman, R.·1995·Magnetic Resonance in Medicine

Abstract

Magnetization transfer in several tissues is measured and successfully modeled using a two‐pool model of exchange. The line shape for the semi‐solid pool is characterized by a superLorentzian and the liquid pool by a Lorentzian. The tissues investigated were white and gray matter, optic nerve, muscle, and liver. All tissues the authors studied are characterized by the same model but differ in the parameter values of the model. Blood and cerebral spinal fluid (CSF) were also investigated. The two‐pool model with a Lorentzian line shape for both the semi‐solid and liquid pools modeled the magnetization transfer in blood. In CSF, as expected, there is no measurable exchange of magnetization. The T 2B associated with the semi‐solid pool was short (˜10 μ) for all tissues indicating a fairly rigid semi‐solid pool. In addition characterization of the line shape as superLorentzian indicates molecules such as integral membrane proteins or lipids in membranes are likely molecules participating in the exchange. Conversely, in blood large globular proteins are indicated due to the Lorentzian nature of the semi‐solid pool and a T 2B ≈ 300 μs.

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Metadata

Authors
Morrison, C., & Mark Henkelman, R.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
1995-04
Volume
33
Issue
4
Pages
475-482
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
OpenAlex
W2130735928
Cited by
305
References
15
FWCI
12.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Model for Magnetization Transfer in Tissues. https://app.cochat.ai/papers/10.1002/mrm.1910330404
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Morrison, C., & Mark Henkelman, R. (1995). A Model for Magnetization Transfer in Tissues. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.1910330404

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