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Cited by 689

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Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II)

Wong, Eric C., Buxton, Richard B., Frank, Lawrence R.·1998·Magnetic Resonance in Medicine

Abstract

In the pulsed arterial spin labeling (ASL) techniques EPISTAR, PICORE, and FAIR, subtraction of two images in which inflowing blood is first tagged and then not tagged yields a qualitative map of perfusion. An important reason this map is not quantitative is that there is a spatially varying delay in the transit of blood from the tagging region to the imaging slice that cannot be measured from a single subtraction. We introduce here two modifications of pulsed ASL (QUIPSS and QUIPSS II) that avoid this problem by applying additional saturation pulses to control the time duration of the tagged bolus, rendering the technique relatively insensitive to transit delays and improving the quantitation of perfusion.

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Metadata

Authors
Wong, E. C., Buxton, R. B., & Frank, L. R.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
1998-05
Volume
39
Issue
5
Pages
702-708
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
OpenAlex
W1994192509
Cited by
689
References
2
FWCI
18.18
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II). https://app.cochat.ai/papers/10.1002/mrm.1910390506
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Wong, E. C., Buxton, R. B., & Frank, L. R. (1998). Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II). Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.1910390506

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