Cited by 1,266Advanced MRI Techniques and ApplicationsAdvanced Neuroimaging Techniques and ApplicationsNMR spectroscopy and applications

T1, T2 relaxation and magnetization transfer in tissue at 3T

Stanisz, Greg J., Odrobina, Ewa E., Pun, Joseph, Escaravage, Michael, Graham, Simon J., Bronskill, Michael J., Henkelman, R. Mark·2005·Magnetic Resonance in Medicine

Abstract

T1, T2, and magnetization transfer (MT) measurements were performed in vitro at 3 T and 37 degrees C on a variety of tissues: mouse liver, muscle, and heart; rat spinal cord and kidney; bovine optic nerve, cartilage, and white and gray matter; and human blood. The MR parameters were compared to those at 1.5 T. As expected, the T2 relaxation time constants and quantitative MT parameters (MT exchange rate, R, macromolecular pool fraction, M0B, and macromolecular T2 relaxation time, T2B) at 3 T were similar to those at 1.5 T. The T1 relaxation time values, however, for all measured tissues increased significantly with field strength. Consequently, the phenomenological MT parameter, magnetization transfer ratio, MTR, was lower by approximately 2 to 10%. Collectively, these results provide a useful reference for optimization of pulse sequence parameters for MRI at 3 T.

Integrity signals

Registry

Crossref · 10.1002/mrm.20605

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Stanisz, G. J., Odrobina, E. E., Pun, J., Escaravage, M., Graham, S. J., Bronskill, M. J., & Henkelman, R. M.
Affiliations
Sunnybrook Health Science Centre (CA)
Corresponding author
Stanisz, Greg J.
Venue
Magnetic Resonance in Medicine
Publisher
Wiley
Published
2005-08-05
Volume
54
Issue
3
Pages
507-512
ISSN
  • 0740-3194 (ISSN-L)
  • 1522-2594
OpenAlex
W2022514814
Cited by
1,266
References
38
Citations by year
2026: 31 · 2025: 67 · 2024: 59 · 2023: 55 · 2022: 56 · 2021: 73 · 2020: 68 · 2019: 76 · 2018: 73 · 2017: 61 · 2016: 74 · 2015: 76 · 2014: 74 · 2013: 74 · 2012: 72
FWCI
22.23
Type
journal article
Language
en
Open access
closed
Locations
  • Magnetic Resonance in Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
  • Physical Sciences › Physics and Astronomy › Nuclear and High Energy Physics › NMR spectroscopy and applications
Keywords
T1 relaxation, T2 relaxation, magnetization transfer, 3T MRI, field strength dependence, magnetization transfer ratio, tissue relaxation times, pulse sequence optimization, mouse tissues, rat tissues, human blood
MeSH terms
Animals, Brain, Cartilage, Cattle, Heart, Humans, Kidney, Liver, Magnetic Resonance Imaging, Spinal Cord, Muscle, Skeletal, Mice, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review