The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
High magnetic field water and metabolite proton T1 and T2 relaxation in rat brain in vivo
Abstract
Comprehensive and quantitative measurements of T1 and T2 relaxation times of water, metabolites, and macromolecules in rat brain under similar experimental conditions at three high magnetic field strengths (4.0 T, 9.4 T, and 11.7 T) are presented. Water relaxation showed a highly significant increase (T1) and decrease (T2) with increasing field strength for all nine analyzed brain structures. Similar but less pronounced effects were observed for all metabolites. Macromolecules displayed field‐independent T2 relaxation and a strong increase of T1 with field strength. Among other features, these data show that while spectral resolution continues to increase with field strength, the absolute signal‐to‐noise ratio (SNR) in T1/T2‐based anatomical MRI quickly levels off beyond ∼7 T and may actually decrease at higher magnetic fields. Magn Reson Med, 2006. © 2006 Wiley‐Liss, Inc.
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Cites
Brain magnetic resonance imaging with contrast dependent on blood oxygenation.
Ogawa, S., Lee, T. M., Kay, A. R., & Tank, D. W. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.24.9868 · Cited by 6,483
Cited by
Villaraza, A. J. L., Bumb, A., & Brechbiel, M. W. (2010) · Chemical Reviews · doi:10.1021/cr900232t · Cited by 632
Pros and cons of ultra-high-field MRI/MRS for human application
Ladd, M. E., Bachert, P., Meyerspeer, M., Moser, E., Nagel, A. M., Norris, D. G., Schmitter, S., Speck, O., Straub, S., & Zaiss, M. (2018) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2018.06.001 · Cited by 544
Uludağ, K., Müller-Bierl, B., & Uğurbil, K. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.051 · Cited by 450
Janik, R., Thomason, L. A. M., Stanisz, A. M., Forsythe, P., Bienenstock, J., & Stanisz, G. J. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2015.11.018 · Cited by 283
Quantitative Gd‐DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA‐SPGR at 9.4T
Lee, H., Mortensen, K., Sanggaard, S., Koch, P., Brunner, H., Quistorff, B., Nedergaard, M., & Benveniste, H. (2018) · Magnetic Resonance in Medicine · doi:10.1002/mrm.26779 · Cited by 110
Metadata
- Authors
- de Graaf, R. A., Brown, P. B., McIntyre, S., Nixon, T. W., Behar, K. L., & Rothman, D. L.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 2006-06-09
- Volume
- 56
- Issue
- 2
- Pages
- 386-394
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2066330039
- Cited by
- 304
- References
- 1
- FWCI
- 10.58
- Type
- journal article
- Language
- en
- Open access
- closed
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