The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Resistance training exercise and creatine in patients with Charcot-Marie-Tooth disease
Abstract
Resistance exercise and creatine supplementation independently improve strength and function in patients with certain neuromuscular diseases. The purpose of this study was to examine the effects of resistance training with and without creatine supplementation on muscle, strength, and function in patients with Charcot–Marie–Tooth (CMT) disease. Twenty patients with CMT consumed 5 g/day creatine or placebo while participating in resistance training for 12 weeks. Energy metabolites, muscle fiber type and size, strength, and timed activities of daily living were measured before and after training. There were no differences between creatine or placebo groups for any outcome. For the groups combined, exercise training increased type I muscle fiber diameter (48.2 ± 14.2 μm vs. 55.4 ± 14.8 μm), strength, and activities of daily living (ADL) times. Thus, patients respond to resistance training with muscle fiber adaptations, and improvements in strength and function. Creatine was not beneficial. © 2004 Wiley Periodicals, Inc. Muscle Nerve 30: 69–76, 2004
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“One study failed to observe greater strength and functionality adaptations from CrM (5 grams/day) above exercise training alone [192]; however, another study showed that CrM enhanced MHCIIa content in CMT patients during resistance training and this correlated with better function [193].”
From Creatine monohydrate supplementation for older adults and clinical populations (2025) · cites this paper as [192]
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Brose, A., Parise, G., & Tarnopolsky, M. A. (2003) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/58.1.b11 · Cited by 274
Self-citationThe nutritional biochemistry of creatine
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Potential benefits of creatine monohydrate supplementation in the elderly
Tarnopolsky, M. A. (2000) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/00075197-200011000-00013 · Cited by 65
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Cited by
Creatine for treating muscle disorders
Kley, R. A., Tarnopolsky, M. A., & Vorgerd, M. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004760.pub4 · Cited by 169
Self-citationSafdar, A., Yardley, N. J., Snow, R., Melov, S., & Tarnopolsky, M. A. (2008) · Physiological Genomics · doi:10.1152/physiolgenomics.00157.2007 · Cited by 149
Self-citationClinical Use of Creatine in Neuromuscular and Neurometabolic Disorders
Tarnopolsky, M. A. (2007) · Subcellular Biochemistry · doi:10.1007/978-1-4020-6486-9_10 · Cited by 67
Self-citationCreatine for treating muscle disorders
Kley, R. A., Vorgerd, M., & Tarnopolsky, M. A. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004760.pub2 · Cited by 45
Self-citationCreatine monohydrate supplementation for older adults and clinical populations
Candow, D. G., Ostojic, S. M., Chilibeck, P. D., Longobardi, I., Gualano, B., Tarnopolsky, M. A., Wallimann, T., Moriarty, T., Kreider, R. B., Forbes, S. C., et al. (2025) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2025.2534130 · Cited by 43
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Metadata
- Authors
- Chetlin, R. D., Gutmann, L., Tarnopolsky, M. A., Ullrich, I. H., & Yeater, R. A.
- Venue
- Muscle & Nerve
- Publisher
- Wiley
- Published
- 2004-05-21
- Volume
- 30
- Issue
- 1
- Pages
- 69-76
- ISSN
- 0148-639X
- 1097-4598
- Cited by
- 50
- References
- 3
- Language
- en
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