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The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) Requiring Invasive Mechanical Ventilation

Open access
Simonnet, Arthur, Chetboun, Mikael, Poissy, Julien, Raverdy, Violeta, Noulette, Jerome, Duhamel, Alain, Labreuche, Julien, Mathieu, Daniel, Pattou, Francois, Jourdain, Merce, the LICORN and the Lille COVID‐19 and Obesity study group·2020·Obesity

Abstract

Objective: The COVID‐19 pandemic is rapidly spreading worldwide, notably in Europe and North America where obesity is highly prevalent. The relation between obesity and severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has not been fully documented. Methods: This retrospective cohort study analyzed the relationship between clinical characteristics, including BMI, and the requirement for invasive mechanical ventilation (IMV) in 124 consecutive patients admitted in intensive care for SARS‐CoV‐2 in a single French center. Results: Obesity (BMI > 30) and severe obesity (BMI > 35) were present in 47.6% and 28.2% of cases, respectively. Overall, 85 patients (68.6%) required IMV. The proportion of patients who required IMV increased with BMI categories (P < 0.01, χ 2 test for trend), and it was greatest in patients with BMI > 35 (85.7%). In multivariate logistic regression, the need for IMV was significantly associated with male sex (P < 0.05) and BMI (P < 0.05), independent of age, diabetes, and hypertension. The odds ratio for IMV in patients with BMI > 35 versus patients with BMI < 25 was 7.36 (1.63‐33.14; P = 0.02). Conclusions: The present study showed a high frequency of obesity among patients admitted in intensive care for SARS‐CoV‐2. Disease severity increased with BMI. Obesity is a risk factor for SARS‐CoV‐2 severity, requiring increased attention to preventive measures in susceptible individuals.

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Metadata

Authors
Simonnet, A., Chetboun, M., Poissy, J., Raverdy, V., Noulette, J., Duhamel, A., Labreuche, J., Mathieu, D., Pattou, F., Jourdain, M., & the LICORN and the Lille COVID‐19 and Obesity study group
Venue
Obesity
Publisher
Wiley
Published
2020-06-10
Volume
28
Issue
7
Pages
1195-1199
ISSN
  • 1930-7381 (ISSN-L)
  • 1930-739X
OpenAlex
W3016182787
Cited by
2,079
References
20
FWCI
57.28
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) Requiring Invasive Mechanical Ventilation. https://app.cochat.ai/papers/10.1002/oby.22831
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Simonnet, A., Chetboun, M., Poissy, J., Raverdy, V., Noulette, J., Duhamel, A., Labreuche, J., Mathieu, D., Pattou, F., Jourdain, M., & the LICORN and the Lille COVID‐19 and Obesity study group. (2020). High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) Requiring Invasive Mechanical Ventilation. Obesity. https://doi.org/10.1002/oby.22831

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