Synthetic polymers as bone engineering scaffold
Abstract
Damage or loss of the bone tissue leads to mobility decline contributing to one of the major issues of human well‐being. Tissue engineering is used to recover fractures and damaged parts of the bone tissue. Various biomaterials and scaffolds have been evaluated for regeneration of hard tissues, however, polymers are the most frequently required biomaterials for the improvement of synthetic bone scaffolds due to their suitable mechanical properties and similar degradation rates to the proteins in hard and soft tissues. Synthetic polymeric materials in bone replacement have several advantages because their physical characteristics can be designed according to their application and their composition can be changed easily. On the other hand, the high adaptability, tenability, and biocompatibility of synthetic materials have received considerable acceptance in the field of tissue engineering. This article presents an update on materials for the fabrication of scaffolds in bone tissue engineering; in addition, we provide information of different kinds of scaffolds and their application usage for hard tissue regeneration.
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PPF matrices degrade in a time frame relevant to bone healing and remodeling.
“Moreover, these matrices have also been described to degrade in the time frame relevant to bone healing and remodeling [36].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [36]
Cites
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Synthesis and Biological Application of Polylactic Acid
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Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
- Authors
- Javid‐Naderi, M. J., Behravan, J., Karimi‐Hajishohreh, N., & Toosi, S.
- Affiliations
- Mashhad University of Medical Sciences (IR)
- University of Waterloo (CA)
- Health Research Center Chamran Hospital Tehran Iran
- Corresponding author
- Toosi, Shirin
- Venue
- Polymers for Advanced Technologies
- Publisher
- Wiley
- Published
- 2023-04-11
- Volume
- 34
- Issue
- 7
- Pages
- 2083-2096
- ISSN
- 1042-7147 (ISSN-L)
- 1099-1581
- OpenAlex
- W4364375163
- Cited by
- 53
- References
- 5
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 13 · 2023: 11
- FWCI
- 4.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Polymers for Advanced Technologies (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Keywords
- synthetic polymers, bone tissue engineering, bone scaffolds, hard tissue regeneration, bone replacement, biocompatibility, scaffold fabrication, biomaterials, fracture healing
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