The EORTC QLQ-C30 (version 3.0) quality of life questionnaire: validation study for Spain with head and neck cancer patients
Abstract
The EORTC Quality of Life Study Group has developed a questionnaire for evaluating Quality of Life in international clinical trials: QLQ-C30. The purpose of the present work is to validate the third version of this questionnaire (3.0) for use in Spain. Two hundred and one head and neck cancer patients completed the QLQ-C30 at one or two time points during the treatment and follow-up periods, and a subsample completed the questionnaire on three occasions. Psychometric evaluation of the structure, reliability and validity of the questionnaire was undertaken. The data support the structure and the reliability of the scales. Validity was confirmed in three ways: the interscale correlations are statistically significant and moderate, several scales and items discriminate among groups of patients with different scores on the clinical variables, and some scales reflect significant changes during treatment and the follow-up period. The EORTC QLQ-C30 (version 3.0) is a reliable and valid questionnaire when applied to a sample of Spanish head and neck cancer patients. These results are in line with previous studies.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The QLQ-C30 has been shown to be reliable and valid in cancer populations.
“It has been shown to be reliable and valid in cancer populations.52–54”
Cites
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., Filiberti, A., Flechtner, H., Fleishman, S. B., Haes, J. C. J. M. D., et al. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.5.365 · Cited by 16,005 · see citing works
Interpreting the significance of changes in health-related quality-of-life scores.
Osoba, D., Rodrigues, G., Myles, J., Zee, B. C.-Y., & Pater, J. L. (1998) · Journal of Clinical Oncology · doi:10.1200/jco.1998.16.1.139 · Cited by 2,973 · see citing works
Karnofsky, D. A., Abelmann, W. H., Craver, L. F., & Burchenal, J. H. (1948) · Cancer · doi:10.1002/1097-0142(194811)1:4 · Cited by 2,249 · see citing works
Bjordal, K., de Graeff, A., Fayers, P. M., Hammerlid, E. B., van Pottelsberghe, C., Curran, D., Ahlner‐Elmqvist, M., Maher, E. J., Meyza, J., Brédart, A., et al. (2000) · European Journal of Cancer · doi:10.1016/s0959-8049(00)00186-6 · Cited by 801 · see citing works
Osoba, D., Zee, B. C.-Y., Pater, J. L., Warr, D. G., Kaizer, L., & Latreille, J. (1994) · Quality of Life Research · doi:10.1007/bf00451727 · Cited by 412 · see citing works
Bjordal, K., & Kaasa, S. (1992) · Acta Oncologica · doi:10.3109/02841869209108178 · Cited by 376 · see citing works
Kobayashi, K., Takeda, F., Teramukai, S., Gotoh, I., Sakai, H., Yoneda, S., Noguchi, Y., Ogasawara, H., & Yoshida, K. (1998) · European Journal of Cancer · doi:10.1016/s0959-8049(97)00395-x · Cited by 256 · see citing works
Testing the EORTC Quality of Life Questionnaire on cancer patients with heterogeneous diagnoses
Ringdal, G. I., & Ringdal, K. (1993) · Quality of Life Research · doi:10.1007/bf00435732 · Cited by 215 · see citing works
Apolone, G., Filiberti, A., Cifani, S., Ruggiata, R., & Mosconi, P. (1998) · Annals of Oncology · doi:10.1023/a:1008264412398 · Cited by 189 · see citing works
The EORTC Modular Approach to Quality of Life Assessment in Oncology
Aaronson, N. K., Cull, A., Kaasa, S., & Sprangers, M. A. G. (1994) · International Journal of Mental Health · doi:10.1080/00207411.1994.11449284 · Cited by 127 · see citing works
Impact of psychosocial intervention on the quality of life of elderly cancer patients
Mantovani, G., Astara, G., Lampis, B., Bianchi, A. C., Curreli, L., Orrù, W., Carpiniello, B., Carta, M. G., Sorrentino, M., & Rudas, N. (1996) · Psycho-Oncology · doi:10.1002/(sici)1099-1611(199606)5:2 · Cited by 58 · see citing works
Quality of life of cancer patients with different prognoses
Ringdal, G. I., Ringdal, K., Kvinnsland, S., & G�testam, K. G. (1994) · Quality of Life Research · doi:10.1007/bf00435257 · Cited by 52 · see citing works
de Boer, J. B., Sprangers, M. A. G., Aaronson, N. K., et al. (1994) · Psychology and Health · doi:10.1080/08870449408407460 · Cited by 27 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
O'Gara, G., Murray, L., Georgopoulou, S., Anstiss, T., Macquarrie, A., Wheatstone, P., Bellman, B., Gilbert, P., Steed, A., & Wiseman, T. (2022) · BMJ Open · doi:10.1136/bmjopen-2020-047626 · Cited by 34 · see citing works
- Authors
- Arraras, J. I., Arias, F., Tejedor, M., Pruja, E., Marcos, M., Martínez, E., & Valerdi, J.
- Venue
- Psycho-Oncology
- Publisher
- Wiley
- Published
- 2002-05
- Volume
- 11
- Issue
- 3
- Pages
- 249-256
- ISSN
- 1057-9249 (ISSN-L)
- 1099-1611
- OpenAlex
- W2108839359
- Cited by
- 140
- References
- 13
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 15 · 2023: 14 · 2022: 11 · 2021: 12 · 2020: 4 · 2019: 6 · 2018: 4 · 2017: 3 · 2016: 7 · 2015: 8 · 2014: 6 · 2013: 4 · 2012: 4
- FWCI
- 1.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psycho-Oncology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- EORTC QLQ-C30, quality of life questionnaires, head and neck cancer, psychometric validation, questionnaire reliability, questionnaire validity, Spanish patients, oncological outcomes, follow-up
- MeSH terms
- Adult, Aged, Aged, 80 and over, Female, Head and Neck Neoplasms, Humans, Male, Middle Aged, Psychometrics, Quality of Life, Surveys and Questionnaires, Sampling Studies, Spain
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
