Depression, illness severity, and healthcare utilization in cystic fibrosis
Abstract
Cystic fibrosis (CF) is an illness associated with high healthcare utilization and healthcare costs, even when compared to other chronic illnesses. In a variety of medical populations, depression has been found to be associated with lower adherence and poorer medical outcomes. The current study is a retrospective chart review of a matched set of 40 patients with CF, half with and half without a depressive disorder diagnosis. Participants were matched on the basis of their age, gender and lung function, and compared in terms of their illness severity (lung function and weight), medical adherence, and healthcare utilization during the year prior to and following diagnosis of depression and a comparable time period for the non-depressed group. Results show an association between depression and BMI, with only the depressed group showing significant decreases in the year following their depressive disorder diagnosis (from a mean BMI z-score of -0.48 to -1.04). Depression was also strongly associated with greater healthcare utilization and healthcare costs relative to those of comparably medically ill controls, in that depressed youth were hospitalized at over three times the rate of non-depressed youth, and their healthcare costs were more than four times higher (mean number of admissions per year for the depressed group of 4.00 vs. 1.20 for the non-depressed group; mean annual costs of $280,000 for the depressed vs. $60,116 for the non-depressed). These findings highlight the importance of addressing the mental health needs of chronically ill patients as a path to better health outcomes and decreasing need for medical services.
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Anxiety and depressive symptoms are associated with increased healthcare costs in individuals with cystic fibrosis.
“increased healthcare costs [5]”
From ACT with CF: A telehealth and in-person feasibility study to address anxiety and depressive symptoms among people with cystic fibrosis (2021) · cites this paper as [5]
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- Authors
- Snell, C., Fernandes, S., Bujoreanu, I. S., & Garcia, G.
- Affiliations
- Boston Children's Hospital (US)
- Boston Children's Hospital and Harvard Medical School 300 Longwood Avenue Boston Massachusetts 02115
- Corresponding author
- Snell, Carolyn
- Venue
- Pediatric Pulmonology
- Publisher
- Wiley
- Published
- 2014-03-12
- Volume
- 49
- Issue
- 12
- Pages
- 1177-1181
- ISSN
- 1099-0496 (ISSN-L)
- 8755-6863
- OpenAlex
- W1697113932
- Cited by
- 108
- References
- 23
- Citations by year
- 2026: 5 · 2025: 1 · 2024: 9 · 2023: 9 · 2022: 12 · 2021: 10 · 2020: 15 · 2019: 10 · 2018: 8 · 2017: 7 · 2016: 9 · 2015: 11 · 2014: 2
- FWCI
- 7.74
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pediatric Pulmonology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- none reported
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Health Professions › Speech and Hearing › Adolescent and Pediatric Healthcare
- Keywords
- cystic fibrosis, depression, health care utilization, health care costs, disease severity, lung function, body mass index, medication adherence, hospitalization, pediatric patients, mental health in chronic illness
- MeSH terms
- Adolescent, Ambulatory Care Facilities, Cystic Fibrosis, Depressive Disorder, Female, Hospitalization, Humans, Male, Registries, Retrospective Studies, Severity of Illness Index, United States, Body Mass Index, Matched-Pair Analysis, Health Care Costs
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