The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Ingested RNA interference for managing the populations of the Colorado potato beetle, Leptinotarsa decemlineata
Abstract
BACKGROUND: RNA interference (RNAi) is a breakthrough technology for conducting functional genomics studies and also as a potential tool for crop protection against insect pests. The major challenge for efficient pest control using RNAi in the field is the development of efficient and reliable methods for production and delivery of double‐stranded RNA (dsRNA). In this paper, the potential of feeding dsRNA expressed in bacteria or synthesized in vitro to manage populations of Colorado potato beetle, Leptinotarsa decemlineata (Say) (CPB), was investigated. RESULTS: Feeding RNAi successfully triggered the silencing of all five target genes tested and caused significant mortality and reduced body weight gain in the treated beetles. This study provides the first example of an effective RNAi response in insects after feeding dsRNA produced in bacteria. CONCLUSION: These results suggest that the efficient induction of RNAi using bacteria to deliver dsRNA is a possible method for management of CPB. This could be also a promising bioassay approach for genome‐wide screens to identify effective target genes for use as novel RNAi‐based insecticides. Copyright © 2010 Society of Chemical Industry
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Cites
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
Livak, K. J., & Schmittgen, T. D. (2001) · Methods · doi:10.1006/meth.2001.1262 · Cited by 180,860
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429
Mao, Y.-B., Cai, W.-J., Wang, J.-W., Hong, G.-J., Tao, X.-Y., Wang, L.-J., Huang, Y.-P., & Chen, X.-Y. (2007) · Nature Biotechnology · doi:10.1038/nbt1352 · Cited by 1,358
Cited by
Mechanisms, Applications, and Challenges of Insect RNA Interference
Zhu, K. Y., & Palli, S. R. (2020) · Annual Review of Entomology · doi:10.1146/annurev-ento-011019-025224 · Cited by 709
Self-citationJoga, M. R., Zotti, M. J., Smagghe, G., & Christiaens, O. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00553 · Cited by 521
Full crop protection from an insect pest by expression of long double-stranded RNAs in plastids
Zhang, J., Khan, S. A., Hasse, C., Ruf, S., Heckel, D. G., & Bock, R. (2015) · Science · doi:10.1126/science.1261680 · Cited by 471
RNA interference technology in crop protection against arthropod pests, pathogens and nematodes
Zotti, M., dos Santos, E. A., Cagliari, D., Christiaens, O., Taning, C. N. T., & Smagghe, G. (2018) · Pest Management Science · doi:10.1002/ps.4813 · Cited by 465
Next-generation insect-resistant plants: RNAi-mediated crop protection
Zhang, J., Khan, S. A., Heckel, D. G., & Bock, R. (2017) · Trends in Biotechnology · doi:10.1016/j.tibtech.2017.04.009 · Cited by 348
Metadata
- Authors
- Zhu, F., Xu, J., Palli, R., Ferguson, J., & Palli, S. R.
- Venue
- Pest Management Science
- Publisher
- Wiley
- Published
- 2010-11-08
- Volume
- 67
- Issue
- 2
- Pages
- 175-182
- ISSN
- 1526-498X (ISSN-L)
- 1526-4998
- OpenAlex
- W2128412621
- Cited by
- 427
- References
- 3
- FWCI
- 4.25
- Type
- journal article
- Language
- en
- Open access
- closed
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