The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.
RNAi Efficiency, Systemic Properties, and Novel Delivery Methods for Pest Insect Control: What We Know So Far
Open accessAbstract
In recent years, the research on the potential of using RNA interference (RNAi) to suppress crop pests has made an outstanding growth. However, given the variability of RNAi efficiency that is observed in many insects, the development of novel approaches toward insect pest management using RNAi requires first to unravel factors behind the efficiency of dsRNA-mediated gene silencing. In this review, we explore essential implications and possibilities to increase RNAi efficiency by delivery of dsRNA through non-transformative methods. We discuss factors influencing the RNAi mechanism in insects and systemic properties of dsRNA. Finally, novel strategies to deliver dsRNA are discussed, including delivery by symbionts, plant viruses, trunk injections, root soaking, and transplastomic plants.
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Cites
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
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Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
Kamath, R. S., Fraser, A. G., Dong, Y., Poulin, G., Durbin, R., Gotta, M., Kanapin, A., Le Bot, N., Moreno, S., Sohrmann, M., et al. (2003) · Nature · doi:10.1038/nature01278 · Cited by 3,616
RNA interference is mediated by 21- and 22-nucleotide RNAs
Elbashir, S. M., Lendeckel, W., & Tuschl, T. (2001) · Genes & Development · doi:10.1101/gad.862301 · Cited by 3,310
Expression profiling reveals off-target gene regulation by RNAi
Jackson, A. L., Bartz, S. R., Schelter, J., Kobayashi, S. V., Burchard, J., Mao, M., Li, B., Cavet, G., & Linsley, P. S. (2003) · Nature Biotechnology · doi:10.1038/nbt831 · Cited by 2,370
Control of coleopteran insect pests through RNA interference
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Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
Grimm, D., Streetz, K. L., Jopling, C. L., Storm, T. A., Pandey, K., Davis, C. R., Marion, P., Salazar, F., & Kay, M. A. (2006) · Nature · doi:10.1038/nature04791 · Cited by 1,677
Endosomal escape pathways for delivery of biologicals
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“The dsRNA-expressing transgenic plants reduce the crop damage, but effective killing of the pest population has not yet been accomplished (Baum et al., 2007; Mao et al., 2007; Pitino et al., 2011; Kumar et al., 2012; Zhu et al., 2012).”
BackgroundRNA Interference: Biology, Mechanism, and Applications
Agrawal, N., Dasaradhi, P. V. N., Mohmmed, A., Malhotra, P., Bhatnagar, R. K., & Mukherjee, S. K. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.4.657-685.2003 · Cited by 1,305
Antisense technologies: Improvement through novel chemical modifications
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Cited by
Applications of Nanotechnology in Plant Growth and Crop Protection: A Review
Shang, Y., Hasan, M. K., Ahammed, G. J., Li, M., Yin, H., & Zhou, J. (2019) · Molecules · doi:10.3390/molecules24142558 · Cited by 1,249
Mechanisms, Applications, and Challenges of Insect RNA Interference
Zhu, K. Y., & Palli, S. R. (2020) · Annual Review of Entomology · doi:10.1146/annurev-ento-011019-025224 · Cited by 709
RNA interference technology in crop protection against arthropod pests, pathogens and nematodes
Zotti, M., dos Santos, E. A., Cagliari, D., Christiaens, O., Taning, C. N. T., & Smagghe, G. (2018) · Pest Management Science · doi:10.1002/ps.4813 · Cited by 465
Self-citationDouble-Stranded RNA Technology to Control Insect Pests: Current Status and Challenges
Christiaens, O., Whyard, S., Vélez, A. M., & Smagghe, G. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.00451 · Cited by 339
Self-citationAshraf, S. A., Siddiqui, A. J., Elkhalifa, A. E. O., Khan, M. I., Patel, M., Alreshidi, M., Moin, A., Singh, R., Snoussi, M., & Adnan, M. (2021) · Science of The Total Environment · doi:10.1016/j.scitotenv.2021.144990 · Cited by 299
Metadata
- Authors
- Joga, M. R., Zotti, M. J., Smagghe, G., & Christiaens, O.
- Venue
- Frontiers in Physiology
- Publisher
- Frontiers Media SA
- Published
- 2016-11-17
- Volume
- 7
- Pages
- 553-553
- ISSN
- 1664-042X (ISSN-L)
- OpenAlex
- W2554569574
- Cited by
- 521
- References
- 120
- FWCI
- 19.26
- Type
- journal article
- Language
- en
- Open access
- gold
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- Joga, M. R., Zotti, M. J., Smagghe, G., & Christiaens, O. (2016). RNAi Efficiency, Systemic Properties, and Novel Delivery Methods for Pest Insect Control: What We Know So Far. Frontiers in Physiology. https://doi.org/10.3389/fphys.2016.00553
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