Crocus sativus L. in the treatment of mild to moderate depression: a double‐blind, randomized and placebo‐controlled trial

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1. Safety and Efficacy of Saffron (Crocus sativus L.) for Treating Mild to Moderate Depression
   Lili Dai, Lingyan Chen, Wenjing Wang · 2020 · The Journal of Nervous and Mental Disease
2. The effects of crocin on psychological parameters in patients under methadone maintenance treatment: a randomized clinical trial
   Anahita Khalatbari-mohseni, Hamid Reza Banafshe, Naghmeh Zahra Mirhosseini, Zatollah Asemi, Amir Ghaderi, Abdollah Omidi · 2019 · Substance Abuse Treatment Prevention and Policy
3. Saffron improves life and sleep quality, glycaemic status, lipid profile and liver function in diabetic patients: A double‐blind, placebo‐controlled, randomised clinical trial
   Aynaz Tajaddini, Neda Roshanravan, Majid Mobasseri, Aydin Aeinehchi, Pouria Sefidmooye Azar, Amir Hadi, Alireza Ostadrahimi · 2021 · International Journal of Clinical Practice
4. Acquired Resilience: An Evolved System of Tissue Protection in Mammals
   Jonathan Stone, John Mitrofanis, Daniel M. Johnstone, Benedetto Falsini, Silvia Bisti, Paul Adam, Arturo Bravo‐Nuevo, Mindy George‐Weinstein, Rebecca Sara Mason, Janis Thane Eells · 2018 · Dose-Response
5. Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry
   Shili Chen, Cong Wei, Peng Gao, Hongwei Kong, Zhenhua Jia, Chunxiu Hu, Weidong Dai, Yiling Wu, Guowang Xu · 2013 · Journal of Pharmaceutical and Biomedical Analysis
6. Subacute Toxicity of Crocus Sativus L. (Saffron) Stigma Ethanolic Extract in Rats
   Daryoush Mohajeri, Ghafour Mousavi, Mehran Mesgari, Y Doustar, Mir Hadi Khayat-Nouri · 2007 · American Journal of Pharmacology and Toxicology
7. CROCUSES IN CONTEXT: A Diachronic Survey of the Crocus Motif in the Aegean Bronze Age
   Jo Day · 2011 · Hesperia The Journal of the American School of Classical Studies at Athens
8. Natural health products, dietary minerals and over-the-counter medications as add-on therapies to antidepressants in the treatment of major depressive disorder: a review
   Péter Döme, László Tombor, Judit Lazáry, Xénia Gonda, Zoltán Rihmer · 2018 · Brain Research Bulletin
9. A systematic review of randomized controlled trials examining the effectiveness of saffron (Crocus sativus L.) on psychological and behavioral outcomes
   Heather Ann Hausenblas, Kacey Heekin, Heather Lee Mutchie, Stephen Douglas Anton · 2015 · Journal of Chinese Integrative Medicine
10. Saffron ethanolic extract attenuates oxidative stress, spatial learning, and memory impairments induced by local injection of ethidium bromide.
    S.M Ghaffari, H. Hatami, Gholamreza Dehghan · 2015 · PubMed Central
11. The effects of saffron (Crocus sativus L.) on mental health parameters and C-reactive protein: A meta-analysis of randomized clinical trials
    Amir Ghaderi, Omid Asbaghi, Željko Reiner, Fariba Kolahdooz, Elaheh Amirani, Hamed Mirzaei, Hamid Reza Banafshe, Parisa Maleki Dana, Zatollah Asemi · 2019 · Complementary Therapies in Medicine
12. <i>Crocus sativus</i> L. Versus Methylphenidate in Treatment of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind Pilot Study
    Baziar, Sara, Aqamolaei, Ali, Khadem, Ebrahim, Mortazavi, Seyyed Hosein, Naderi, Sina, Sahebolzamani, Erfan, Mortezaei, Amirhosein, Jalilevand, Shakiba, Mohammadi, Mohammad-Reza, Shahmirzadi, Mahsa et al. · 2019 · Journal of Child and Adolescent Psychopharmacology
13. Uses of Complementary and Alternative Medicine in Multiple Sclerosis
    Foroogh Namjooyan, Rahil Ghanavati, Nastaran Majdinasab, Shiva Jokari, Mohammad Janbozorgi · 2014 · Journal of Traditional and Complementary Medicine
14. A placebo controlled randomized clinical trial of Crocus sativus L. (saffron) on depression and food craving among overweight women with mild to moderate depression
    Shahin Akhondzadeh, Seyed‐Ali Mostafavi, Seyed Ali Keshavarz, Mohammad Reza Mohammadi, Saeed Hosseini, Mohammad Reza Eshraghian · 2019 · Journal of Clinical Pharmacy and Therapeutics
15. Effect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials
    Ali Abedi, Hassan Ghobadi, Afshan Sharghi, Sohrab Iranpour, Mehdi Fazlzadeh, Mohammad Reza Aslani · 2023 · Frontiers in Medicine
16. Saffron (Crocus sativus L.) Tea Intake Prevents Learning/Memory Defects and Neurobiochemical Alterations Induced by Aflatoxin B1 Exposure in Adult Mice
    Zacharoula I. Linardaki, Fotini N. Lamari, Marigoula Margarity · 2017 · Neurochemical Research
17. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment
    Mohammad Reza Safarinejad, Nayyer Shafiei, Saba Safarinejad · 2010 · International Journal of Impotence Research
18. Neuropharmacology Effects of Saffron (Crocus sativus) and Its Active Constituents
    Marjan Nassiri‐Asl, Hossein Hosseinzadeh · 2014 · Elsevier eBooks
19. Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention
    Cyrus Jalili, Ali Ghanbari, Shiva Roshankhah, Mohammad Reza Salahshoor · 2019 · Iranian Biomedical Journal
20. The effect of Crocus sativus (saffron) on the severity of premenstrual syndrome
    Soheila Pirdadeh Beiranvand, Nabiollah Shams Beiranvand, Zahra Behboodi Moghadam, Mehdi Birjandi, Seddigheh Azhari, Elham Rezaei, Alinazar Salehnia, Somayyeh Beiranvand · 2015 · European Journal of Integrative Medicine
21. Herbal Medicines in the Treatment of Psychiatric and Neurological Disorders
    Shahin Akhondzadeh · 2007 · Springer eBooks
22. Short-term Outcomes of Saffron Supplementation in Patients with Age-related Macular Degeneration: A Double-blind, Placebo-controlled, Randomized Trial.
    Alireza Lashay, Gholamreza Sadough, Elham Ashrafi, Mohammad Reza Lashay, Morteza Movassat, Shahin Akhondzadeh · 2016 · Medical Hypothesis Discovery & Innovation in Ophthalmology
23. Nutritional strategies for dealing with depression
    Luana Meller Manosso, Morgana Moretti, Ana Lúcia S. Rodrigues · 2013 · Food & Function
24. Diversity of culturable bacterial endophytes of saffron in Kashmir, India
    Tanwi Sharma, Sanjana Kaul, Manoj K. Dhar · 2015 · SpringerPlus
25. The effects of twenty-one nutrients and phytonutrients on cognitive function: A narrative review
    John Eugene Lewis, Jillian Poles, Delaney P Shaw, Elisa Karhu, Sher Ali Khan, Annabel E Lyons, Susana Barreiro Sacco, H. Reginald McDaniel · 2021 · Journal of Clinical and Translational Research
26. Health benefits of herbs and spices
    Abin Kurian · 2012 · Elsevier eBooks
27. Impact of saffron as an anti-cancer and anti-tumor herb
    Chermahini, S.H., Majid, F.A.A., Sarmidi, M.R., Taghizadeh, E., Salehnezhad, S. · 2010 · The University of Malaya Research Repository (University of Malaya)
28. Comparative efficacy and safety of Crocus sativus L. for treating mild to moderate major depressive disorder in adults: a meta-analysis of randomized controlled trials
    Xiangying Yang, Xiao-Lu Chen, Yixiao Fu, Qinghua Luo, Lian Du, Haitang Qiu, Tian Qiu, Li Zhang, Huaqing Meng · 2018 · Neuropsychiatric Disease and Treatment
29. Effects of saffron (Crocus sativus L.) on cognitive function. A systematic review of RCTs
    Konstantinos Ioannis Avgerinos, Christos Vrysis, Nikolaos Chaitidis, Katerina Kolotsiou, Pavlos G. Myserlis, Dimitrios Kapogiannis · 2020 · Neurological Sciences
30. Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L.
    Renata Matraszek, Mirosława Chwil, Karol Terlecki, Michał Marian Skoczylas · 2022 · Pharmaceuticals
31. Safranal Enhances Non‐Rapid Eye Movement Sleep in Pentobarbital‐Treated Mice
    Zheng Liu, Xin‐Hong Xu, Tianya Liu, Zong‐Yuan Hong, Yoshihiro Urade, Zhi‐Li Huang, Wei‐Min Qu · 2012 · CNS Neuroscience & Therapeutics
32. Curcumin Gel in the Treatment of Minor Aphthous Ulcer: a Randomized, Placebo- Controlled Trial
    Soheila Manifar, Andreas Obwaller, A Gharehgozloo, H R Boorboor Shirazi Kordi, Shahin Akhondzadeh · 2012 · DOAJ (DOAJ: Directory of Open Access Journals)
33. The Healing Effects of Spices in Chronic Diseases
    Danka Bukvički, Davide Gottardi, Sahdeo Prasad, Miroslav Novaković, Petar D. Marin, Amit Kumar Tyagi · 2018 · Current Medicinal Chemistry
34. The efficacy of Crocus sativus (Saffron) versus placebo and Fluoxetine in treating depression: a systematic review and meta-analysis
    Mojtaba Khaksarian, Masoud Behzadifar, Meysam Behzadifar, Maryam Alipour, Firouzeh Jahanpanah, Tania Simona Re, Fabio Firenzuoli, Riccardo Zerbetto, Nicola Luigi Bragazzi · 2019 · Psychology Research and Behavior Management
35. Detailed profile of crocus sativus
    Katariya Dhirajkumar Champalal, Nerkar Nilakshi, Gadiya Raj Vijay, Abhyankar M. M · 2011 · International Journal of Pharma and Bio Sciences
36. The time course of action of two neuroprotectants, dietary saffron and photobiomodulation, assessed in the rat retina.
    Fabiana Di Marco, Stefania Romeo, Charith Nandasena, Sivaraman Purushothuman, Charean Adams, Silvia Bisti, Jonathan Stone · 2013 · Europe PMC (PubMed Central)
37. Quality traits of saffron (Crocus sativus L.) produced in the Italian Alps
    Annamaria Giorgi, Daniela Pentimalli, Luca Giupponi, Sara Panseri · 2017 · Open Agriculture
38. Phytochemistry, quality control and medicinal uses of Saffron ( Crocus sativus L .): an updated review
    Andi Hermansyah, Long Chiau Ming, Rabha Aissa, Mohamed Ibourki, Hasna Ait Bouzid, Laila Bijla, Samira Oubannin, El Hassan Sakar, Si Mohamed Jadouali, Khang Wen Goh et al. · 2023 · Journal of Medicine and Life
39. Petal and Stigma of Crocus sativus L. in the Treatment of Depression: A Pilot Double - blind Randomized Trial
    A Akhoundzadeh Basti, Ghoreyshi S.A.A., Ahmad Ali Nourbala, S H Akhoundzadeh, Sh Rezazadeh · 2008 · DOAJ (DOAJ: Directory of Open Access Journals)
40. Saffron and its active ingredients against human disorders: A literature review on existing clinical evidence.
    Seyedeh Farzaneh Omidkhoda, Hossein Hosseinzadeh · 2022 · PubMed Central
41. Therapeutic potential of saffron in brain disorders: From bench to bedside
    Erjola Bej, Anna Rita Volpe, Patrizia Cesare, Annamaria Cimini, Michele d’Angelo, Vanessa Castelli · 2024 · Phytotherapy Research
42. Saffron, Passionflower, Valerian and Sage for Mental Health
    Amirhossein Modabbernia, Shahin Akhondzadeh · 2013 · Psychiatric Clinics of North America
43. Effects of Saffron Aqueous Extract and Its Main Constituent, Crocin, on Health-Related Quality of Life, Depression, and Sexual Desire in Coronary Artery Disease Patients: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial
    Nasim Abedimanesh, Alireza Ostadrahimi, Seyedeh Zahra Bathaie, Saeed Abedimanesh, Behrooz Motlagh, Mohammad Asghari Jafarabadi, Mohammadreza Taban Sadeghi · 2017 · Iranian Red Crescent Medical Journal
44. Neuroendocrine and cellular mechanisms in stress resilience: From hormonal influence in the CNS to mitochondrial dysfunction and oxidative stress
    Arghya Bhattacharya, Manas Chakraborty, Ananya Chanda, Taha Alqahtani, Ajoy Kumer, Bikram Dhara, Moitreyee Chattopadhyay · 2024 · Journal of Cellular and Molecular Medicine
45. Nepeta menthoides Boiss. & Buhse freeze-dried aqueous extract versus sertraline in the treatment of major depression: A double blind randomized controlled trial
    Sepideh Kolouri, Ali Firoozabadi, Alireza Salehi, Mohammad Mehdi Zarshenas, Seyed Ali Dastgheib, Mojtaba Heydari, Hossein Rezaeizadeh · 2016 · Complementary Therapies in Medicine
46. A preliminary assessment of a combination of rhodiola and saffron in the management of mild–moderate depression
    Marie Bangratz, Samira Ait Abdellah, Aurélie Berlin, Claude Blondeau, Angèle Guilbot, Michel Dubourdeaux, Patrick Lemoine · 2018 · Neuropsychiatric Disease and Treatment
47. Was Hawan Designed to Fight Anxiety-Scientific Evidences?
    Ramandeep Kaur Romana, A. Sharma, Vikas Kumar Gupta, Rajinder Kaur, Sunil kumar V, Parveen Bansal · 2017 · Journal of Religion and Health
48. Herbal remedies in depression – state of the art.
    Tomasz Szafrański · 2014 · Psychiatria Polska
49. Herbal medicines and botanicals for managing insomnia, stress, anxiety, and depression: A critical review of the emerging evidence focusing on the Middle East and Africa
    Morten Georg Jensen, Michael Goode, Michael Heinrich · 2024 · PharmaNutrition
50. Phytonutrients and their neuroprotective role in brain disorders
    Krishnendu Adhikary, Krishnendu Ganguly, Riya Sarkar, Md. Abubakar, Pradipta Banerjee, Prithviraj Karak · 2025 · Frontiers in Molecular Biosciences
51. Saffron
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52. An In Vitro Study of Saffron Carotenoids: The Effect of Crocin Extracts and Dimethylcrocetin on Cancer Cell Lines
    Kyriaki Hatziagapiou, Olti Alexandra Nikola, Sofia Marka, Eleni Koniari, Eleni Kakouri, Maria-Eleftheria Zografaki, Sophie Mavrikou, Charalabos D. Kanakis, Emmanouil Flemetakis, George Panagiotis Chrousos et al. · 2022 · Antioxidants
53. Inhibitory effect ofCrocus sativusL. ethanol extract on adjuvant-induced arthritis
    Shahrzad Zamani Taghizadeh Rabe, Maryam Sahebari, Zohreh Mahmoudi, Hossein Hosseinzadeh, Dariush Haghmorad, Nafiseh Sadat Tabasi, Maryam Rastin, Mahdieh Khazaee, Mahmoud Mahmoudi · 2014 · Food and Agricultural Immunology
54. Complementary and Alternative Medicine Usage for Behavioral Health Indications
    Michele Larzelere, James S. Campbell, Marta Robertson · 2010 · Primary Care Clinics in Office Practice
55. Effects of a Saffron Alcoholic Extract on Visual Short-Term Memory in Humans: a Psychophysical Study
    Martha Ghodrat, Hedayat Sahraei, Javad Razjouyan, Gholam Hossein Meftahi · 2014 · Neurophysiology
56. Saffron for the Management of Premenstrual Dysphoric Disorder: A Randomized Controlled Trial
    Fatemeh Rajabi, Marjan Rahimi, MohammadReza Sharbafchizadeh, Mohammad Javad Tarrahi · 2020 · Advanced Biomedical Research
57. Herbal approaches to system dysfunctions
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58. New horizons for the study of saffron (Crocus sativus L.) and its active ingredients in the management of neurological and psychiatric disorders: A systematic review of clinical evidence and mechanisms
    Shufen Han, Yifei Cao, Xingrong Wu, Jiaoyang Xu, Zizheng Nie, Yue Qiu · 2024 · Phytotherapy Research
59. Clinical depression: an evidence-based integrative complementary medicine treatment model.
    Jerome J. Sarris · 2011 · PubMed
60. Formulas Used by Tibetan Doctors at Men‐Tsee‐Khang in India for the Treatment of Neuropsychiatric Disorders and Their Correlation with Pharmacological Data
    Raquel de Luna Antonio, Elisa Harumi Kozasa, José Carlos Fernandes Galduróz, Dawa, Yeshi Dorjee, Tsultrim Kalsang, Tsering Norbu, Tashi Tenzin, Eliana Rodrigues · 2012 · Phytotherapy Research
61. The effect of crocin versus sertraline in treatment of mild to moderate postpartum depression: a double-blind, randomized clinical trial
    Golnoosh Kolahdooz, Iraj Vosough, Samaneh Sepahi, Seyed Ahmad Mohajeri · 2022 · International Clinical Psychopharmacology
62. A preliminary study on antioxidant activities of saffron petal extracts in lambs
    ‌Arash Omidi, Seddighe Rahdari, Mohammad Hassanpour Fard · 2014 · Veterinary Science Development
63. Bioactive Components of Saffron and Their Pharmacological Properties
    Azam Bolhassani · 2018 · Studies in natural products chemistry
64. Saffron supplementation ameliorates oxidative damage to sperm DNA following a 16-week low-to-intensive cycling training in male road cyclists
    Behzad Hajizadeh Maleki, Bakhtyar Tartibian, Frank Christoph Mooren, Fakhreddin Yaghoob Nezhad, Mehdi Yaseri · 2015 · Journal of Functional Foods
65. In vitro Antimicrobial and Free Radical Scavenging Activities of the Total Flavonoid in Petal and Stamen of Crocus sativus
    K Chen, Xiaoguo Wang, Fengyao Chen, Jinrong Bai · 2017 · Indian Journal of Pharmaceutical Sciences
66. Saffron and its major constituents against neurodegenerative diseases: A mechanistic review
    Sadaf Abdian, Sajad Fakhri, Seyed Zachariah Moradi, Mohammad Reza Khirehgesh, Javier Echeverría · 2024 · Phytomedicine
67. Effect of Saffron (Crocus Satious L.) as an Add-On Therapy to Sertraline in Mild to Moderate Generalized Anxiety Disorder: A Double Blind Randomized Controlled Trial
    Nasibe Jafarnia, Zeinab Ghorbani, Morteza Nokhostin, Azadeh Manayi, Saeedeh Nouri-Majd, Soodeh Razeghi Jahromi · 2017 · Archives of Neuroscience
68. The Effect of Saffron on Depression among Recovered Consumers of Methamphetamine Living with HIV/AIDS
    Farzad Jalali, Seyedeh Fatemeh Hashemi · 2018 · Substance Use & Misuse
69. Safety and toxicity of saffron
    Soghra Mehri, Bibi Marjan Razavi, Hossein Hosseinzadeh · 2020 · Elsevier eBooks
70. Superfoods and their impact on brain health: a systematic review
    Raghupathi Niranjan Kumar, Haja Nazeer Ahamed · 2025 · Discover Food
71. Distribution, chemical composition and medicinal importance of saffron (Crocus sativus L.)
    Sabbi Jan, Aijaz Ahmad Wani, Azra N. Kamili, Mahpara Kashtwari · 2014 · African Journal of Plant Science
72. Efficacy and safety of saffron as adjunctive therapy in adults with attention-deficit/hyperactivity disorder: a randomized, double-blind, placebo-controlled clinical trial
    Benyamin Pazoki, Nadia Zandi, Z. Assaf, H. Moghaddam, A. Zeinoddini, M. Mohammadi, S. Akhondzadeh · 2022 · Advances in Integrative Medicine
73. A Review on the Effects of Saffron Extract and its Constituents on Factors Related to Neurologic, Cardiovascular and Gastrointestinal Diseases
    Alireza Milajerdi, Maryam Mahmoudi · 2015 · DOAJ (DOAJ: Directory of Open Access Journals)
74. Evaluation of the effectiveness of crocin isolated from saffron in treatment of burning mouth syndrome: A randomized controlled trial.
    Atessa Pakfetrat, Mehdi Talebi, Zohreh Dalirsani, Seyed Ahmad Mohajeri, Roya Zamani, Ala Ghazi · 2019 · Europe PMC (PubMed Central)
75. Electrocardiogram alterations following one-week consumption of Crocus sativus L. (saffron)
    Siyavash Joukar · 2012 · Europe PMC (PubMed Central)
76. Food-Based Strategies for Depression Management From Iranian Traditional Medicine Resources
    Mandana Tavakkoli-Kakhki, Malihe Motavasselian, Mahmoud Mosaddegh, Mohammad Mehdi Esfehani, Mohammad Kamalinejad, Mohsen Nematy · 2014 · Iranian Red Crescent Medical Journal
77. Crocins for Ischemic Stroke: A Review of Current Evidence
    Kiran Shahbaz, Dennis Chang, Xian Zhou, Mitchell Low, Sai Wang Seto, Chung Guang Li · 2022 · Frontiers in Pharmacology
78. Stigma and petals of Crocus sativus L.: Review and comparison of phytochemistry and pharmacology
    Xue Li, Jin Xie, Hong Fan, Tan Jin, Dingkun Zhang, Bao Jun Yang, Funeng Geng, Jin Pei, Hongyan Ma · 2023 · Arabian Journal of Chemistry
79. Therapeutic properties of saffron and its chemical constituents
    Gabriel Akyirem Akowuah, Thet Thet Htar · 2014 · Journal of Natural Products
80. Clinical Evidence on the Effects of Saffron (Crocus Sativus L.) in Anxiety and Depression
    Wadhwa Pankaj, Vanktesh Kumar, Navjot Kaur · 2021 · World Journal of Traditional Chinese Medicine
81. Saffron (Crocus sativus L.) stigma reduces symptoms of morphine-induced dependence and spontaneous withdrawal in rats
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82. Stress-induced alterations in hippocampal BDNF in the pathophysiology of major depressive disorder and the antidepressant effect of saffron
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83. Herbal Medicine in the Treatment of Alzheimer’s Disease
    Reza Hajiaghaee, Shahin Akhondzadeh · 2012 · DOAJ (DOAJ: Directory of Open Access Journals)
84. Herbal Medicine in Depression
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85. Powerful Stress Relieving Medicinal Plants for Anger, Anxiety, Depression, and Stress During Global Pandemic
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86. Saffron
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87. COUNTING THREADS. SAFFRON IN AEGEAN BRONZE AGE WRITING AND SOCIETY
    Jo Day · 2011 · Oxford Journal of Archaeology
88. Therapeutic effects of saffron (Crocus sativus) versus fluoxetine on Irritable Bowel Syndrome: A double-blind randomized clinical trial
    Borna Tadayon Najafabadi, Kiandokht Ghamari, Tahereh Kermany Ranjabari, Ahmad Ali Noorbala, Naser Ebrahimi Daryani, Elmira Vanaki, Shahin Akhondzadeh · 2019 · Advances in Integrative Medicine
89. Evaluation of Crocin Content and In Vitro Antioxidant and Anti-Glycation Activity of Different Saffron Extracts
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90. Review of Herbal Medicines for the Treatment of Depression
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91. A naturalistic study of herbal medicine for self-reported depression and/or anxiety a protocol
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92. Saffron as a Promising Therapy for Inflammatory Bowel Disease
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93. Effect of Multi-Ingredient Supplement Containing Satiereal, Naringin, and Vitamin D on Body Composition, Mood, and Satiety in Overweight Adults
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94. New mechanistic insights into hepatoprotective activity of milk thistle and chicory quantified extract: The role of hepatic Farnesoid-X activated receptors.
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95. Therapeutic Potential of Saffron Extract in Mild Depression: A Study of Its Role on Anhedonia in Rats and Humans
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96. Crocus sativus (saffron) in the treatment of female sexual dysfunction: a three-center, double-blind, randomized, and placebo-controlled clinical trial.
    Ladan Kashani, Sahar Aslzadeh, Kamyar Shokraee, Ahmad Shamabadi, Borna Tadayon Najafabadi, Morteza Jafarinia, Sophia Esalatmanesh, Shahin Akhondzadeh · 2022 · PubMed Central
97. Herbal medicine in the treatment of primary dysmenorrhea
    Ladan Kashani, Mahboubeh Mohammadi, M Heidari, Shahin Akhondzadeh · 2015 · DOAJ (DOAJ: Directory of Open Access Journals)
98. Comparison of the Anxiolytic Effects of Saffron (Crocus sativus. L) and Diazepam Before Herniorrhaphy Surgery: A Double Blind Randomized Clinical Trial
    Mahdi Basirimoghadam, Arash Hamzei, Alireza Moslem, Saeid Pasban-Noghabi, Nematollah Ghorbani, Jafar Ghenaati · 2016 · Zahedan Journal of Research in Medical Sciences
99. Avicenna and evidence based medicine.
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100. Level of clinical evidence of herbal complementary therapies in psychiatric disorders
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