The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine
Abstract
Barberry (Berberis vulgaris L. family Berberidaceae) is well known in Iran and various parts of this plant including its root, bark, leaf and fruit have been used as folk medicine. The two decades of research has demonstrated different pharmacological and therapeutic effects of B. vulgaris and its isoquinoline alkaloids (particularly berberine). Studies carried out on the chemical composition of the plant show that the most important constituents of this plant are isoquinoline alkaloids such as berberine, berbamine and palmatine. Berberine represents one of the most studied among the naturally occurring protoberberine alkaloids. In addition to B. vulgaris(barberry), berberine is present in many other plants and is used for the treatment of different diseases. This article reviews the traditional uses and pharmacological effects of total extract and the most active ingredient of B. vulgaris(berberine). Copyright © 2008 John Wiley & Sons, Ltd.
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Kong, W., Wei, J., Abidi, P., Lin, M., Inaba, S., Li, C., Wang, Y., Wang, Z., Si, S., Pan, H., et al. (2004) · Nature Medicine · doi:10.1038/nm1135 · Cited by 1,391
Cardiovascular effects of berberine in patients with severe congestive heart failure
Marin ‐ NETO, J. A., Maciel, B. C., Secches, A. L., & Gallo, L. (1988) · Clinical Cardiology · doi:10.1002/clc.4960110411 · Cited by 128
Lin, H.-L., Liu, T.-Y., Wu, C.-W., & Chi, C.-W. (1999) · British Journal of Cancer · doi:10.1038/sj.bjc.6690710 · Cited by 100
Wu, X., Li, Q., Xin, H., Yu, A., & Zhong, M. (2005) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-005-0952-3 · Cited by 90
The effects of berberine on the pharmacokinetics of ciclosporin A in healthy volunteers
Xin, H.-W., Wu, X.-C., Li, Q., Yu, A.-R., & Zhong, M.-Y. (2006) · Methods and Findings in Experimental and Clinical Pharmacology · doi:10.1358/mf.2006.28.1.962774 · Cited by 63
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Neag, M. A., Mocan, A., Echeverría, J., Pop, R. M., Bocsan, C. I., Crişan, G., & Buzoianu, A. D. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00557 · Cited by 562
Berberine and Its Role in Chronic Disease
Cicero, A. F. G., & Baggioni, A. (2016) · Advances in Experimental Medicine and Biology · doi:10.1007/978-3-319-41334-1_2 · Cited by 285
Toxicological Effects of Berberine and Sanguinarine
Singh, N., & Sharma, B. (2018) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2018.00021 · Cited by 227
Derosa, G., Maffioli, P., & Cicero, A. F. (2012) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2012.704014 · Cited by 171
Metadata
- Authors
- Imanshahidi, M., & Hosseinzadeh, H.
- Venue
- Phytotherapy Research
- Publisher
- Wiley
- Published
- 2008-07-29
- Volume
- 22
- Issue
- 8
- Pages
- 999-1012
- ISSN
- 0951-418X (ISSN-L)
- 1099-1573
- OpenAlex
- W2143877891
- Cited by
- 634
- References
- 5
- FWCI
- 7.66
- Type
- journal article
- Language
- en
- Open access
- closed
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