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Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine

Imanshahidi, Mohsen, Hosseinzadeh, Hossein·2008·Phytotherapy Research

Abstract

Barberry (Berberis vulgaris L. family Berberidaceae) is well known in Iran and various parts of this plant including its root, bark, leaf and fruit have been used as folk medicine. The two decades of research has demonstrated different pharmacological and therapeutic effects of B. vulgaris and its isoquinoline alkaloids (particularly berberine). Studies carried out on the chemical composition of the plant show that the most important constituents of this plant are isoquinoline alkaloids such as berberine, berbamine and palmatine. Berberine represents one of the most studied among the naturally occurring protoberberine alkaloids. In addition to B. vulgaris(barberry), berberine is present in many other plants and is used for the treatment of different diseases. This article reviews the traditional uses and pharmacological effects of total extract and the most active ingredient of B. vulgaris(berberine). Copyright © 2008 John Wiley & Sons, Ltd.

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Metadata

Authors
Imanshahidi, M., & Hosseinzadeh, H.
Venue
Phytotherapy Research
Publisher
Wiley
Published
2008-07-29
Volume
22
Issue
8
Pages
999-1012
ISSN
  • 0951-418X (ISSN-L)
  • 1099-1573
OpenAlex
W2143877891
Cited by
634
References
5
FWCI
7.66
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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