Clinical features of deaths in the novel coronavirus epidemic in China
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Summary: In response to the recent novel coronavirus outbreak originating in Wuhan, Hubei province, China, observations concerning novel coronavirus mortality are of urgent public health importance. The present work presents the first review of the fatal novel coronavirus cases in China. Clinical data of fatal cases published by the Chinese Government were studied. As of 2 February 2020, the clinical data of 46 fatal cases were identified. The case fatality rate was significantly higher in Hubei province than the rest of China. While 67% of all deceased patients were male, gender was unlikely to be associated with mortality. Diabetes was likely to be associated with mortality. There is, however, not yet sufficient evidence to support the association between hypertension and mortality as similar prevalence of hypertension was also observed in the Hubei population.
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Prolonged disease, delayed viral clearance, and a higher fatality rate are age-related in COVID-19.
“Additionally, prolonged disease, delayed viral clearance, and a higher fatality rate is also reported to be age related [21].”
From Age-dependent Immune Response to the Biontech/Pfizer BNT162b2 Coronavirus Disease 2019 Vaccination (2021) · cites this paper as [21]
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The Incubation Period of COVID-19: Current Understanding and Modeling Technique
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- Authors
- Leung, C.
- Affiliations
- Deakin University (AU)
- Corresponding author
- Leung, Char
- ORCID
- Leung, Char
- Venue
- Reviews in Medical Virology
- Publisher
- Wiley
- Published
- 2020-03-16
- Volume
- 30
- Issue
- 3
- Pages
- e2103-e2103
- ISSN
- 1052-9276 (ISSN-L)
- 1099-1654
- PMC
- PMC7228265
- OpenAlex
- W3012499226
- Cited by
- 171
- References
- 7
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 8 · 2023: 6 · 2022: 29 · 2021: 40 · 2020: 81
- FWCI
- 5.12
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Reviews in Medical Virology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Keywords
- novel coronavirus, COVID-19 pandemic, mortality, fatal case, clinical features, case fatality rate, Hubei Province, diabetes mellitus, hypertension, sex differences, risk factors
- MeSH terms
- COVID-19, Age Factors, Aged, China, Female, Hospitalization, Humans, Male, Middle Aged, Pneumonia, Viral, Comorbidity, Coronavirus Infections, Pandemics
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