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Cited by 1,257

The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.

New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection

Dollard, Sheila C., Grosse, Scott D., Ross, Danielle S.·2007·Reviews in Medical Virology
DOI 10.1002/rmv.544
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Abstract

Congenital CMV is a major cause of neurological and sensory impairment in children. Reliable estimates of the prevalence of permanent sequelae and mortality associated with congenital CMV are needed to guide development of education and prevention programmes and to gauge the financial costs associated with this disease. To calculate such estimates, this review used data solely from studies in which children with congenital CMV were identified through universal screening. Based on 15 studies with a total of 117 986 infants screened, the overall CMV birth prevalence estimate was 0.7%. The percentage of infected children with CMV‐specific symptoms at birth was 12.7%. The percentage of symptomatic children with permanent sequelae was 40–58%. The percentage of children without symptoms at birth who developed permanent sequelae was estimated to be 13.5%. The true burden of congenital CMV infection is unclear because data on important outcomes, such as visual impairment, are lacking and follow‐up of infected children has been too short to fully identify late‐onset sequelae. Therefore, the estimates of permanent sequelae associated with congenital CMV presented here are likely underestimates. Future studies should extend follow‐up of CMV‐infected children identified through universal screening and include the evaluation of visual impairment. Copyright © 2007 John Wiley & Sons, Ltd.

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Metadata

Authors
Dollard, S. C., Grosse, S. D., & Ross, D. S.
Venue
Reviews in Medical Virology
Publisher
Wiley
Published
2007-06
Volume
17
Issue
5
Pages
355-363
ISSN
  • 1052-9276 (ISSN-L)
  • 1099-1654
DOI
10.1002/rmv.544
OpenAlex
W2056774192
Cited by
1,257
References
20
FWCI
20.52
Type
journal article
Language
en
Open access
closed

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