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Cited by 916

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Models for temporal variation in cancer rates. II: Age–period–cohort models

Clayton, D., Schifflers, E.·1987·Statistics in Medicine

Abstract

Our first paper reviewed methods for modelling variation in cancer incidence and mortality rates in terms of either period effects or cohort effects in the general multiplicative risk model. There we drew attention to the difficulty of attributing regular trends to either period or cohort influences. In this paper we turn to the more realistic problem in which neither period nor cohort effects alone lead to an adequate description of the data. We describe the age‐period‐cohort model and show how its ambiguities surrounding regular trends ‘intensify’. We recommend methods for presenting the results of analyses based upon this model which minimize the serious risk of misleading implications and critically review previous suggestions. The discussion is illustrated by an analysis of breast cancer mortality in Japan with special reference to the phenomenon of ‘Clemmesen's hook’.

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Metadata

Authors
Clayton, D., & Schifflers, E.
Venue
Statistics in Medicine
Publisher
Wiley
Published
1987-06
Volume
6
Issue
4
Pages
469-481
ISSN
  • 0277-6715 (ISSN-L)
  • 1097-0258
OpenAlex
W2139621631
Cited by
916
References
13
FWCI
2.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Models for temporal variation in cancer rates. II: Age–period–cohort models. https://app.cochat.ai/papers/10.1002/sim.4780060406
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Clayton, D., & Schifflers, E. (1987). Models for temporal variation in cancer rates. II: Age–period–cohort models. Statistics in Medicine. https://doi.org/10.1002/sim.4780060406

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.