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Cited by 254

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Comparison of baseline and repeated measure covariate techniques in the Framingham heart study

Cupples, L. Adrienne, D'Agostino, Ralph B., Anderson, Keaven, Kannel, William B.·1988·Statistics in Medicine

Abstract

The purpose of this paper is to indicate how repeated measures on risk factors have been employed in the prediction of the development of disease in the Framingham Heart Study. Since these measures vary over time, the method accounts for time dependent covariates. The technique is a generalized person‐years approach in that it treats each observation interval (of equal length) as a mini‐follow‐up study in which the current risk factor measurements are employed to predict an event in the interval. Observations over multiple intervals are pooled into a single sample to predict the short term risk of an event. This approach is compared to the long‐term prediction of disease which utilizes only the baseline measurements and ignores subsequent repeated measures on the risk factors.

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Metadata

Authors
Cupples, L. A., D'Agostino, R. B., Anderson, K., & Kannel, W. B.
Venue
Statistics in Medicine
Publisher
Wiley
Published
1988-01
Volume
7
Issue
1-2
Pages
205-218
ISSN
  • 0277-6715 (ISSN-L)
  • 1097-0258
OpenAlex
W2105028310
Cited by
254
References
0
FWCI
3.51
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.