The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents
Open accessAbstract
Carbon nanotubes have shown promise as contrast agents for photoacoustic and photothermal imaging of tumours and infections because they offer high resolution and allow deep tissue imaging. However, in vivo applications have been limited by the relatively low absorption displayed by nanotubes at near-infrared wavelengths and concerns over toxicity. Here, we show that gold-plated carbon nanotubes—termed golden carbon nanotubes—can be used as photoacoustic and photothermal contrast agents with enhanced near-infrared contrast (~102-fold) for targeting lymphatic vessels in mice using extremely low laser fluence levels of a few mJ cm−2. Antibody-conjugated golden carbon nanotubes were used to map the lymphatic endothelial receptor, and preliminary in vitro viability tests show golden carbon nanotubes have minimal toxicity. This new nanomaterial could be an effective alternative to existing nanoparticles and fluorescent labels for non-invasive targeted imaging of molecular structures in vivo.
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Cites
Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods
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Cited by
Yao, J., & Wang, L. V. (2013) · Laser & Photonics Reviews · doi:10.1002/lpor.201200060 · Cited by 616
Recent advances in selective photothermal therapy of tumor
Zhao, L., Zhang, X., Wang, X., Guan, X., Zhang, W., & Ma, J. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01080-3 · Cited by 445
Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo
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Ultrahigh Sensitivity Carbon Nanotube Agents for Photoacoustic Molecular Imaging in Living Mice
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Diketopyrrolopyrrole‐Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging
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Metadata
- Authors
- Kim, J.-W., Galanzha, E. I., Shashkov, E. V., Moon, H.-M., & Zharov, V. P.
- Venue
- Nature Nanotechnology
- Published
- 2009-08-23
- Volume
- 4
- Issue
- 10
- Pages
- 688-694
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- OpenAlex
- W2070772667
- Cited by
- 710
- References
- 43
- FWCI
- 24.65
- Type
- journal article
- Language
- en
- Open access
- green
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- Kim, J.-W., Galanzha, E. I., Shashkov, E. V., Moon, H.-M., & Zharov, V. P. (2009). Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents. Nature Nanotechnology. https://doi.org/10.1038/nnano.2009.231
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