Cited by 25Quantum Dots Synthesis And PropertiesAdvanced biosensing and bioanalysis techniquesGold and Silver Nanoparticles Synthesis and Applications

Quantum‐Dot‐Encoded Silica Nanospheres for Nucleic Acid Hybridization

Pillai, Pramod P., Reisewitz, Stephanie, Schroeder, Hendrik, Niemeyer, Christof M.·2010·Small

Abstract

Oligonucleotide-modified submicrometer-sized silica nanospheres that are color-encoded by embedded luminescent QDs and that can be further functionalized by DNA–protein conjugates are described. This approach provides a facile route to specifically encode and functionalize particles for biological and biomedical applications.

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Registry

Crossref · 10.1002/smll.201000949

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32 of 32 references verified0 citation errors · 0 not checkable

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  • Using hybridization assays with fluorescently-labelled probes, the authors estimated the number of barcodes available for hybridization on each file to be on the order of 10^8.

    “Using hybridization assays with fluorescently-labelled probes35–37, we estimated the number of barcodes available for hybridization on each file to be on the order of 108 (Supplementary Fig. 7).”

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Authors
Pillai, P. P., Reisewitz, S., Schroeder, H., & Niemeyer, C. M.
Affiliations
TU Dortmund University (DE)
Corresponding author
Niemeyer, Christof M.
Venue
Small
Publisher
Wiley
Published
2010-09-02
Volume
6
Issue
19
Pages
2130-2134
ISSN
  • 1613-6810 (ISSN-L)
  • 1613-6829
OpenAlex
W2076785222
Cited by
25
References
32
Citations by year
2025: 3 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2013: 1 · 2012: 4
FWCI
1.41
Type
journal article
Language
en
Open access
closed
Locations
  • Small (publishedVersion)
  • PubMed (publishedVersion)
Funders
Alexander von Humboldt-Stiftung
Topics
  • Physical Sciences › Materials Science › Materials Chemistry › Quantum Dots Synthesis And Properties
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
  • Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
Keywords
quantum dots, silica nanospheres, nucleic acid hybridization, luminescent quantum dots, protein-DNA conjugates, particle functionalization, submicron particles
MeSH terms
Luminescent Measurements, Nucleic Acid Hybridization, Silicon Dioxide, Quantum Dots, Nanospheres

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