The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential
Open accessAbstract
Since more than 30% of consumer products that include engineered nanomaterials contain nano‐Ag, the safety of this material is of considerable public concern. In this study, Ag nanoparticles (NPs) are used to demonstrate that 20 nm polyvinylpyrrolidone (PVP or P) and citrate (C)‐coated Ag NPs induce more cellular toxicity and oxidative stress than larger (110 nm) particles due to a higher rate of dissolution and Ag bioavailability. Moreover, there is also a higher propensity for citrate 20 nm (C20) nanoparticles to generate acute neutrophilic inflammation in the lung and to produce chemokines compared to C110. P110 has less cytotoxic effects than C110, likely due to the ability of PVP to complex released Ag+. In contrast to the more intense acute pulmonary effects of C20, C110 induces mild pulmonary fibrosis at day 21, likely as a result of slow but persistent Ag+ release leading to a sub‐chronic injury response. Interestingly, the released metallic Ag is incorporated into the collagen fibers depositing around airways and the lung interstitium. Taken together, these results demonstrate that size and surface coating affect the cellular toxicity of Ag NPs as well as their acute versus sub‐chronic lung injury potential.
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Kittler, S., Greulich, C., Diendorf, J., Köller, M., & Epple, M. (2010) · Chemistry of Materials · doi:10.1021/cm100023p · Cited by 1,126
Glover, R. D., Miller, J. M., & Hutchison, J. E. (2011) · ACS Nano · doi:10.1021/nn2031319 · Cited by 303
Cited by
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Ferdous, Z., & Nemmar, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072375 · Cited by 1,019
In vivo degeneration and the fate of inorganic nanoparticles
Feliu, N., Docter, D., Heine, M., del Pino, P., Ashraf, S., Kolosnjaj-Tabi, J., Macchiarini, P., Nielsen, P., Alloyeau, D., Gazeau, F., et al. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00699f · Cited by 423
Wang, L., Zhang, T., Li, P., Huang, W., Tang, J., Wang, P., Liu, J., Yuan, Q., Bai, R., Li, B., et al. (2015) · ACS Nano · doi:10.1021/acsnano.5b02483 · Cited by 290
Formation of the Protein Corona: The Interface between Nanoparticles and the Immune System
Barbero, F., Russo, L., Vitali, M., Piella, J., Salvo, I., Borrajo, M. L., Busquets-Fité, M., Grandori, R., Bastús, N. G., Casals, E., et al. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.10.001 · Cited by 263
Metadata
- Authors
- Wang, X., Ji, Z., Chang, C. H., Zhang, H., Wang, M., Liao, Y., Lin, S., Meng, H., Li, R., Sun, B., Winkle, L. V., Pinkerton, K. E., Zink, J. I., Xia, T., & Nel, A. E.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2013-08-27
- Volume
- 10
- Issue
- 2
- Pages
- 385-398
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2138071609
- Cited by
- 272
- References
- 2
- FWCI
- 14.36
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, X., Ji, Z., Chang, C. H., Zhang, H., Wang, M., Liao, Y., Lin, S., Meng, H., Li, R., Sun, B., Winkle, L. V., Pinkerton, K. E., Zink, J. I., Xia, T., & Nel, A. E. (2014). Use of Coated Silver Nanoparticles to Understand the Relationship of Particle Dissolution and Bioavailability to Cell and Lung Toxicological Potential. Small. https://doi.org/10.1002/smll.201301597
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