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Cited by 222

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Signal Transduction Pathways in Apoptosis

Open access
McConkey, David J., Orrenius, Sten·1996·STEM CELLS

Abstract

Emerging evidence indicates that apoptosis is regulated by some of the same signal transduction pathways previously implicated in other physiological cellular responses, including alterations in intracellular Ca2+ compartmentalization, activation of protein kinases and phosphatases, alteratios in pH and oxidative stress. Interestingly, signals that promote apoptosis in one model can suppress cell death in another, indicating that cellular responses are determined by the intrinsic programming of the cell in question. This review will summarize current knowledge of the signal transduction pathways regulating apoptosis and discuss how they may be coupled to components of the molecular machinery for cell death.

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Crossref · 10.1002/stem.140619

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Metadata

Authors
McConkey, D. J., & Orrenius, S.
Venue
STEM CELLS
Published
1996-11
Volume
14
Issue
6
Pages
619-631
ISSN
  • 1066-5099 (ISSN-L)
  • 1549-4918
OpenAlex
W2013936743
Cited by
222
References
7
FWCI
12.49
Type
journal article
Language
en
Open access
bronze

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