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Cited by 285

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Middle cerebral artery blood flow velocities and pulsatility index and the cerebroplacental pulsatility ratio: longitudinal reference ranges and terms for serial measurements

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Ebbing, C., Rasmussen, S., Kiserud, T.·2007·Ultrasound in Obstetrics & Gynecology

Abstract

Objectives: To establish reference ranges suitable for serial assessments of the fetal middle cerebral (MCA) and umbilical (UA) artery blood flow velocities, pulsatility index (PI) and cerebroplacental pulsatility ratio and to provide terms for calculating conditional reference intervals suitable for individual serial measurements. Methods: This was a longitudinal study of 161 singleton pregnancies. Using Doppler ultrasound, MCA and UA blood velocities and PI were determined three to five times at 3–5‐week intervals over a gestational age range of 19–41 weeks. Polynomial regression lines for the 95th, 50th and 5th percentiles were calculated for the peak systolic velocity (PSV), time‐averaged maximum velocity (TAMXV), PI and cerebroplacental ratio. Terms for calculating conditional reference intervals were established. Results: Based on 566 observations our new longitudinal reference ranges for fetal middle cerebral PSV, TAMXV and PI provided terms for calculating conditional reference intervals (i.e. predicting expected 95% confidence limits based on a previous measurement), and correspondingly for the cerebroplacental ratio (n = 550). The reference ranges were at some variance with those of previous cross‐sectional studies. The narrow 95% confidence limits for the 5th and 95th percentiles ensured reliable ranges. Conclusions: We have established longitudinal reference ranges appropriate for the serial assessment of MCA blood velocities and PI and cerebroplacental ratio. Particularly the terms for calculating conditional ranges based on a previous observation make this system more appropriate for longitudinal monitoring than are cross‐sectional data. Copyright © 2007 ISUOG. Published by John Wiley & Sons, Ltd.

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Metadata

Authors
Ebbing, C., Rasmussen, S., & Kiserud, T.
Venue
Ultrasound in Obstetrics & Gynecology
Publisher
Wiley
Published
2007-08-24
Volume
30
Issue
3
Pages
287-296
ISSN
  • 0960-7692 (ISSN-L)
  • 1469-0705
OpenAlex
W2150959824
Cited by
285
References
30
FWCI
5.95
Type
journal article
Language
en
Open access
bronze

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Ebbing, C., Rasmussen, S., & Kiserud, T. (2007). Middle cerebral artery blood flow velocities and pulsatility index and the cerebroplacental pulsatility ratio: longitudinal reference ranges and terms for serial measurements. Ultrasound in Obstetrics & Gynecology. https://doi.org/10.1002/uog.4088

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