The DOI matches its Crossref record.
Integrated Cell Isolation and Polymerase Chain Reaction Analysis Using Silicon Microfilter Chambers
Open accessAbstract
White blood cells are isolated from whole blood in silicon-glass 4.5-microliter microchips containing a series of 3.5-micron feature-sized 'weir-type' filters, formed by an etched silicon dam spanning the flow chamber. Genomic DNA targets, e.g., dystrophin gene, can be directly amplified using the polymerase chain reaction (PCR) from the white cells isolated on the filters. This dual function microchip provides a means to simplify nucleic acid analyses by integrating in a single device two key steps in the analytical procedure, namely, cell isolation and PCR.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Microfluidics for cell separation
Bhagat, A. A. S., Bow, H., Hou, H. W., Tan, S. J., Han, J., & Lim, C. T. (2010) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-010-0611-4 · Cited by 632
A novel 3D mammalian cell perfusion-culture system in microfluidic channels
Toh, Y.-C., Zhang, C., Zhang, J., Khong, Y. M., Chang, S., Samper, V. D., van Noort, D., Hutmacher, D. W., & Yu, H. (2007) · Lab on a Chip · doi:10.1039/b614872g · Cited by 414
Microfluidics for flow cytometric analysis of cells and particles
Huh, D., Gu, W., Kamotani, Y., Grotberg, J. B., & Takayama, S. (2005) · Physiological Measurement · doi:10.1088/0967-3334/26/3/r02 · Cited by 396
Fully integrated PCR-capillary electrophoresis microsystem for DNA analysis
Lagally, E. T., Emrich, C. A., & Mathies, R. A. (2001) · Lab on a Chip · doi:10.1039/b109031n · Cited by 284
Metadata
- Authors
- Wilding, P., Kricka, L. J., Cheng, J., Hvichia, G., Shoffner, M. A., & Fortina, P.
- Venue
- Analytical Biochemistry
- Publisher
- Elsevier BV
- Published
- 1998-03
- Volume
- 257
- Issue
- 2
- Pages
- 95-100
- ISSN
- 0003-2697 (ISSN-L)
- OpenAlex
- W2043591822
- Cited by
- 276
- References
- 0
- FWCI
- 15.56
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Integrated Cell Isolation and Polymerase Chain Reaction Analysis Using Silicon Microfilter Chambers. https://app.cochat.ai/papers/10.1006/abio.1997.2530
- The paper
- Wilding, P., Kricka, L. J., Cheng, J., Hvichia, G., Shoffner, M. A., & Fortina, P. (1998). Integrated Cell Isolation and Polymerase Chain Reaction Analysis Using Silicon Microfilter Chambers. Analytical Biochemistry. https://doi.org/10.1006/abio.1997.2530
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
