Cited by 37Neurobiology of Language and BilingualismHemispheric Asymmetry in NeuroscienceFunctional Brain Connectivity Studies

Cerebral networks and functional brain asymmetry: evidence from regional metabolic changes during word repetition

Karbe, Hans, Herholz, Karl, Weber-Luxenburger, Gerald, Ghaemi, Morad, Heiss, Wolf-Dieter·1998·Brain and Language

Abstract

Word repetition causes a significant bilateral metabolic increase in both superior temporal cortices. Frontal speech areas are less activated despite their presumable speech competence. We investigated in this study the relationship between frontal and temporal cortical areas during word repetition. We measured regional cerebral metabolic rates of glucose (CMRGI) in 15 normal subjects with positron emission tomography (PET) at rest and during word repetition. Significant correlations connected frontal and temporal areas of both hemispheres, notwithstanding their different levels of mean metabolic activation. The left planum temporale was a hub of significant interregional correlations, in contrast to its contralateral mate. This study indicates that an asymmetric network of significant connections orchestrates the speech-relevant cortical areas according to the actual needs of speech processing.

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Crossref · 10.1006/brln.1997.1937

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Authors
Karbe, H., Herholz, K., Weber-Luxenburger, G., Ghaemi, M., & Heiss, W.-D.
Affiliations
  • University Hospital Cologne (DE)
  • Max Planck Society (DE)
Venue
Brain and Language
Publisher
Elsevier BV
Published
1998-06
Volume
63
Issue
1
Pages
108-121
ISSN
0093-934X (ISSN-L)
OpenAlex
W2066563149
Cited by
37
References
45
Citations by year
2026: 1 · 2021: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 2 · 2012: 2
FWCI
1.99
Type
journal article
Language
en
Open access
closed
Locations
  • Brain and Language (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
Keywords
word repetition, functional brain asymmetry, brain networks, regional cerebral glucose metabolism, planum temporale, superior temporal cortex, interhemispheric connectivity, speech processing, hemispheric lateralization
MeSH terms
Adult, Brain Mapping, Female, Frontal Lobe, Glucose, Humans, Functional Laterality, Male, Models, Neurological, Speech, Temporal Lobe, Tomography, Emission-Computed

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