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Angiopoietin-Like Proteins: Cardiovascular Biology and Therapeutic Targeting for the Prevention of Cardiovascular Diseases

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Angiopoietin-like protein 3 regulates the motility and permeability of podocytes by altering nephrin expression in vitro

Gao, X., Xu, H. M., Liu, H., Rao, J., Li, Y., & Zha, X. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.07.027 · Cited by 35 · see citing works

Associations between Common Genetic Polymorphisms in Angiopoietin-Like Proteins 3 and 4 and Lipid Metabolism and Adiposity in European Adolescents and Adults

Legry, V., Bokor, S., Cottel, D., Béghin, L., Catasta, G., Nagy, E., González‐Gross, M., Spinneker, A., Stehle, P., Molnár, D., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0769 · Cited by 35 · see citing works

Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice

Zuo, Y., Zhang, C., Zhou, Y., Li, H., Xiao, W., Herzog, R. W., Xu, J., Zhang, J., Chen, Y. E., & Han, R. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01036-0 · Cited by 33 · see citing works

Fasting-induced adipose factor/angiopoietin–like protein 4: a potential target for dyslipidemia?

Zandbergen, F. J., van Dijk, S. J., Müller, M. M., & Kersten, S. (2006) · Future Lipidology · doi:10.2217/17460875.1.2.227 · Cited by 33 · see citing works

Emerging roles of angiopoietin‐like proteins in inflammation: Mechanisms and potential as pharmacological targets

Yang, J. X., Song, Q., Niu, S., Chen, H., Petersen, R. B., Zhang, Y., & Huang, K. (2021) · Journal of Cellular Physiology · doi:10.1002/jcp.30534 · Cited by 32 · see citing works

Different relationship between ANGPTL3 and HDL components in female non-diabetic subjects and type-2 diabetic patients

Zhao, D., Yang, L., Wang, X., Yuan, S., Yu, C., Wang, Z., Lang, J., & Feng, Y. (2016) · Cardiovascular Diabetology · doi:10.1186/s12933-016-0450-1 · Cited by 28 · see citing works

The Lipid-Modulating Effect of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression through Regulation of LXRα Activation in Hepatic Cells

Chen, P., Chao, T.-Y., Hsu, H., Wang, C., Lin, C.-Y., Gao, W.-Y., Wu, M., & Yen, J.-H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189853 · Cited by 25 · see citing works

Postprandial exercise regulates tissue-specific triglyceride uptake through angiopoietin-like proteins

Liu, X., Zhang, Y., Han, B., Li, L., Li, Y., Ma, Y., Kang, S., Li, Q., Kong, L., Huang, K., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.181553 · Cited by 25 · see citing works

Cloning, chromosome mapping and expression characteristics of porcine ANGPTL3 and -4

Feng, S., Chen, X., Xia, T., Gan, L., Qiu, H., Dai, M. H., Zhou, L., Peng, Y., & Yang, Z. Q. (2006) · Cytogenetic and Genome Research · doi:10.1159/000091927 · Cited by 24 · see citing works

ANGPLT3: A novel modulator of lipid metabolism

Hassan, M. S. (2017) · Global Cardiology Science and Practice · doi:10.21542/gcsp.2017.6 · Cited by 24 · see citing works

Paeoniflorin regulates GALNT2-ANGPTL3-LPL pathway to attenuate dyslipidemia in mice

Xiao, H., Liang, L., Luo, Z.-F., & Sun, Z. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.08.006 · Cited by 24 · see citing works

Angioarrestin: A unique angiopoietin-related protein with anti-angiogenic properties

Dhanabal, M., Jeffers, M., LaRochelle, W. J., & Lichenstein, H. S. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.05.134 · Cited by 24 · see citing works

New Therapeutic Approaches to the Treatment of Dyslipidemia 1: ApoC-III and ANGPTL3

Kim, J. Y., & Kim, N. H. (2023) · Journal of Lipid and Atherosclerosis · doi:10.12997/jla.2023.12.1.23 · Cited by 23 · see citing works

Effect of Intracavernous Administration of Angiopoietin-4 on Erectile Function in the Streptozotocin-Induced Diabetic Mouse

Kwon, M.-H., Ryu, J., Kim, W. J., Jin, H., Song, K., Kwon, K.-D., Batbold, D., Yin, G. N., Koh, G. Y., & Suh, J. (2013) · The Journal of Sexual Medicine · doi:10.1111/jsm.12278 · Cited by 23 · see citing works

Glyceraldehyde 3-Phosphate Dehydrogenase Is a Cellular Target of the Insulin Mimic Demethylasterriquinone B1

Kim, H.-S., Deng, L., Xiong, X., Hunter, W. D., Long, M. C., & Pirrung, M. C. (2007) · Journal of Medicinal Chemistry · doi:10.1021/jm070437i · Cited by 23 · see citing works

Angiopoietin-like protein 3 modulates barrier properties of human glomerular endothelial cells through a possible signaling pathway involving phosphatidylinositol-3 kinase/protein kinase B and integrin αVβ3

Li, Y., Sun, L., Xu, H. M., Fang, Z., Yao, W., Guo, W., Rao, J., & Zha, X. (2008) · Acta Biochimica et Biophysica Sinica · doi:10.1111/j.1745-7270.2008.00421.x · Cited by 23 · see citing works

Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition

Mysore, R., Liebisch, G., Zhou, Y., Olkkonen, V. M., & Haridas, P. A. N. (2017) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2017.05.002 · Cited by 22 · see citing works

Structure and Function of Angiopoietin-like Protein 3 (ANGPTL3) in Atherosclerosis

Lu, X. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190621120523 · Cited by 22 · see citing works

Evinacumab: Mechanism of action, clinical, and translational science

Dingman, R., Bihorel, S., Gusarova, V., Mendell, J., & Pordy, R. (2024) · Clinical and Translational Science · doi:10.1111/cts.13836 · Cited by 23 · see citing works

Catalase deficiency facilitates the shuttling of free fatty acid to brown adipose tissue through lipolysis mediated by ROS during sustained fasting

Dutta, R. K., Lee, J. N., Maharjan, Y., Park, C., Choe, S., Ho, Y., & Park, R. (2021) · Cell & Bioscience · doi:10.1186/s13578-021-00710-5 · Cited by 21 · see citing works

Angiopoietin-like 3: An important protein in regulating lipoprotein levels

Burks, K. H., Basu, D., Goldberg, I. J., & Stitziel, N. O. (2022) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2022.101688 · Cited by 21 · see citing works

Efficacy and Safety of Evinacumab for the Treatment of Hypercholesterolemia: A Meta-Analysis

Jin, M., Meng, F., Yang, W., Liang, L., Wang, H., & Zhenyan, F. (2021) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001073 · Cited by 21 · see citing works

Targeting PCSK9 and Beyond for the Management of Low-Density Lipoprotein Cholesterol

Mohamed, F., Mansfield, B. S., & Raal, F. J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12155082 · Cited by 20 · see citing works

Novel Experimental Agents for the Treatment of Hypercholesterolemia

Pećin, I., & Reiner, Ž. (2021) · Journal of Experimental Pharmacology · doi:10.2147/jep.s267376 · Cited by 19 · see citing works

Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study

Hess, A. L., Carayol, J., Blædel, T., Hager, J., Cara, A. D., Astrup, A. V., Saris, W. H. M., Larsen, L. H., & Valsesia, A. (2018) · Genes & Nutrition · doi:10.1186/s12263-018-0597-3 · Cited by 18 · see citing works

Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions

Ruhanen, H., Haridas, P. A. N., Jauhiainen, M., & Olkkonen, V. M. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2020.158791 · Cited by 18 · see citing works

Liver-targeted Angptl4 silencing by antisense oligonucleotide treatment attenuates hyperlipidaemia and atherosclerosis development in APOE*3-Leiden.CETP mice

Modder, M., Panhuis, W. I. H., Li, M., Afkir, S., Dorn, A. L., Pronk, A. C. M., Streefland, T. C. M., Lalai, R. A., Pierrou, S. E., Nilsson, S. K., et al. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvae195 · Cited by 17 · see citing works

Macromolecular Interactions of Lipoprotein Lipase (LPL)

Wheless, A., Gunn, K. H., & Neher, S. B. (2024) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-58843-3_8 · Cited by 18 · see citing works

Role of the angiopoietin-like protein family in the progression of NAFLD

Su, X., Xu, Q., Li, Z., Ren, Y., Jiao, Q., Wang, L., & Wang, Y. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e27739 · Cited by 18 · see citing works

Tissue expression and predicted protein structures of the bovine ANGPTL3 and association of novel SNPs with growth and meat quality traits

Chen, N., Ma, Y., Yang, T., Lin, F., Fu, W., Xu, Y., Li, F., Li, J. Y., & Gao, S. (2015) · animal · doi:10.1017/s1751731115000658 · Cited by 16 · see citing works

How ANGPTL3 Inhibition Will Help Our Clinical Practice?

Bini, S., Tramontano, D., Minicocci, I., Costanzo, A. D., Tambaro, F., D’Erasmo, L., & Arca, M. (2023) · Current Atherosclerosis Reports · doi:10.1007/s11883-022-01076-w · Cited by 15 · see citing works

Targeting angiopoietin‐like 3 in atherosclerosis: From bench to bedside

Ling, P., Zheng, X., Luo, S., Ge, J., Xu, S., & Weng, J. (2021) · Diabetes Obesity and Metabolism · doi:10.1111/dom.14450 · Cited by 15 · see citing works

From Congenital Disorders of Fat Malabsorption to Understanding Intra-Enterocyte Mechanisms Behind Chylomicron Assembly and Secretion

Levy, E. H., Beaulieu, J., & Spahis, S. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.629222 · Cited by 14 · see citing works

The Citrus Flavonoid Nobiletin Downregulates Angiopoietin-like Protein 3 (ANGPTL3) Expression and Exhibits Lipid-Modulating Effects in Hepatic Cells and Adult Zebrafish Models

Lin, C.-Y., Chen, P., Hsu, H., Gao, W.-Y., Wu, M., & Yen, J.-H. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232012485 · Cited by 14 · see citing works

S-300 gel matrix irreversibly binds single-stranded nucleic acids

Nehls, M. C., & Boehm, T. L. J. (1993) · Trends in Genetics · doi:10.1016/0168-9525(93)90024-c · Cited by 5 · see citing works

Cloning, chromosome mapping and expression characteristics of porcine ANGPTL3 and -4

Feng, S., Chen, X., Xia, T., Gan, L., Qiu, H., Dai, M. H., Zhou, L., Peng, Y., & Yang, Z. Q. (2006) · Cytogenetic and Genome Research · doi:10.1159/000091927 · Cited by 24 · see citing works

Identification of a novel human angiopoietin-like gene expressed mainly in heart

Zeng, L., Dai, J., Ying, K., Zhao, E., Jin, W., Ye, Y., Dai, J., Xu, J., Xie, Y., & Mao, Y. (2003) · Journal of Human Genetics · doi:10.1007/s100380300025 · Cited by 36 · see citing works

Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin‐3

Kim, I., Kwak, H. J., Ahn, J. E., So, J.-N., Liu, M., Koh, K. N., & Koh, G. Y. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00008-3 · Cited by 79 · see citing works

Molecular characterization and expression of angiopoietin-like protein 3 in the chicken, Gallus gallus

Sato, K., Seol, H. S., Sato, K., Kamada, T., & Akiba, Y. (2008) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2008.06.005 · Cited by 5 · see citing works