Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 213

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Mechanism of Ribonuclease Inhibition by Ribonuclease Inhibitor Protein Based on the Crystal Structure of its Complex with Ribonuclease A

Kobe, Bostjan, Deisenhofer, Johann·1996·Journal of Molecular Biology
DOI 10.1006/jmbi.1996.0694
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1006/jmbi.1996.0694

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 1 references

Research works printed but not linked: 84

  1. Acharya, 1994, Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease, Proc. Natl. Acad. Sci. USA, 91, 2915, 10.1073/pnas.91.8.2915 · DOI
  2. Bernstein, 1977, The Protein Data Bank: a computer-based archival file for macromolecular structures, J Mol. Biol., 112, 535, 10.1016/S0022-2836(77)80200-3 · DOI · Paper page
  3. Birdsall, 1992, Crystal structure disposition of thymidilic acid tetramer in complex with ribonuclease A, J Biol. Chem., 267, 22230, 10.1016/S0021-9258(18)41659-6 · DOI
  4. Blackburn, 1980, The role of lysine-41 of ribonuclease A in the interaction with RNase inhibitor from human placenta, J. Biol. Chem., 255, 10959, 10.1016/S0021-9258(19)70400-1 · DOI
  5. Blackburn, 1982, Identification of lysine residues in the binding domain of ribonucle-ase A for the RNase inhibitor from human placenta, J Biol. Chem., 257, 316, 10.1016/S0021-9258(19)68364-X · doi:10.1016/s0021-9258(19)68364-x
  6. Blackburn, 1979, Ribonuclease inhibitor from human placenta: Interaction with derivatives of ribonuclease A, J Biol. Chem., 254, 12488, 10.1016/S0021-9258(19)86341-X · DOI
  7. Blackburn, 1982, Pancreatic ribonuclease, vol. 15, 317
  8. Blackburn, 1977, Ribonuclease inhibitor from human placenta, J Biol. Chem., 252, 5904, 10.1016/S0021-9258(17)40110-4 · DOI · Paper page
  9. Boix, 1996, Role of the N terminus in RNase A homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity, J Mol. Biol., 257, 992, 10.1006/jmbi.1996.0218 · doi:10.1006/jmbi.1996.0218
  10. Borkakoti, 1983, The active site of ribonuclease A from the crystallographic studies of ribonuclease-A-inhibitor complexes, Eur. J. Biochem., 132, 89, 10.1111/j.1432-1033.1983.tb07329.x · doi:10.1111/j.1432-1033.1983.tb07329.x
  11. Brtinger, 1990, Extension of molecular replacement: A new search strategy base on Patterson correlation coefficient, Acta Crystallog. sect. A, 46, 46, 10.1107/S0108767389009633 · DOI · Paper page
  12. Brtinger, 1987, Crystallographic R-factor refinement by molecular dynamics, Science, 235, 458, 10.1126/science.235.4787.458 · DOI · Paper page
  13. Buckle, 1994, Substrate binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-Å resolution, Biochemistry, 33, 1644, 10.1021/bi00173a005 · DOI
  14. Buckle, 1994, Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-Å resolution, Biochemistry, 33, 8878, 10.1021/bi00196a004 · DOI · Paper page
  15. CCP4, 1994, The CCP4 suite: Programs for protein crystallography, Acta Crystallog. sect. D, 50, 760, 10.1107/S0907444994003112 · DOI · Paper page
  16. Campbell, 1993, Epidermal growth factor-like modules, Curr. Opin. Struct. Biol., 3, 385, 10.1016/S0959-440X(05)80111-3 · DOI · Paper page
  17. Capasso, 1983, Refinement of the structure of bovine seminal ribonuclease, Biopolymers, 22, 327, 10.1002/bip.360220142 · DOI
  18. Chothia, 1974, Hydrophobic bonding and accessible surface area in proteins, Nature, 248, 338, 10.1038/248338a0 · DOI · Paper page
  19. Chothia, 1975, Structural invariants in protein folding, Nature, 254, 304, 10.1038/254304a0 · DOI · Paper page
  20. Crawford, 1989, Multiple splice forms of ribonuclease-inhibitor mRNA differ in the 5′-untranslated region, Gene, 85, 525, 10.1016/0378-1119(89)90447-2 · DOI
  21. Fett, 1985, Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells, Biochemistry, 24, 5480, 10.1021/bi00341a030 · DOI · Paper page
  22. Fontecilla-Camps, 1994, Crystal structure of ribonuclease A-d(ApTpApApG) complex. Direct evidence for extended substrate recognition, J Biol. Chem., 269, 21526, 10.1016/S0021-9258(17)31836-7 · DOI
  23. Furie, 1988, The molecular basis of blood coagulation, Cell, 53, 505, 10.1016/0092-8674(88)90567-3 · DOI · Paper page
  24. Guillet, 1993, Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar, Structure, 1, 165, 10.1016/0969-2126(93)90018-C · doi:10.1016/0969-2126(93)90018-c
  25. Harper, 1989, A covalent angiogenin/ribonuclease hybrid with a fourth disulfide bond generated by regional mutagenesis, Biochemistry, 28, 1875, 10.1021/bi00430a067 · DOI
  26. Hartley, 1989, Barnase and barstar: two small proteins to fold and fit together, Trends Biochem. Sci., 14, 450, 10.1016/0968-0004(89)90104-7 · DOI · Paper page
  27. Hill, 1983, The structural and sequence homology of a family of microbial ribonucleases, Trends Biochem. Sci., 8, 364, 10.1016/0968-0004(83)90363-8 · DOI
  28. Hofsteenge, 1988, Amino acid sequence of the ribonuclease inhibitor from porcine liver reveals the presence of leucine-rich repeats, Biochemistry, 27, 8537, 10.1021/bi00423a006 · DOI
  29. Hofsteenge, 1989, Primary structure of ribonuclease from porcine liver, a new member of ribonuclease superfamily, Biochemistry, 28, 9806, 10.1021/bi00451a040 · doi:10.1021/bi00451a040
  30. Hofsteenge, 1991, Studies on the interaction of ribonuclease inhibitor with pancreatic ribonuclease involving differential labeling of cysteinyl residues, J Biol. Chem., 266, 24198, 10.1016/S0021-9258(18)54412-4 · doi:10.1016/s0021-9258(18)54412-4
  31. Hofsteenge, 1991, Purification and characterization of truncated ribonuclease inhibitor, Biochem. J., 275, 541, 10.1042/bj2750541 · doi:10.1042/bj2750541
  32. Howlin, 1989, Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model, Acta Crystallog. sect. A, 45, 851, 10.1107/S0108767389009177 · DOI
  33. Janin, 1995, Elusive affinities, Proteins: Struct. Funct. Genet., 21, 30, 10.1002/prot.340210105 · DOI
  34. Janin, 1990, The structure of protein-protein recognition sites, J Biol. Chem., 265, 16027, 10.1016/S0021-9258(17)46181-3 · DOI · Paper page
  35. Janin, 1988, Surface, subunit interfaces and interior of oligomeric proteins, J Mol. Biol., 204, 155, 10.1016/0022-2836(88)90606-7 · DOI · Paper page
  36. Kartha, 1967, Tertiary structure of ribonuclease, Nature, 213, 862, 10.1038/213862a0 · DOI · Paper page
  37. Kawanomoto, 1992, cDNA cloning and sequence of rat ribonuclease inhibitor, and tissue distribution of the mRNA, Biochim. Biophys. Acta, 1129, 335, 10.1016/0167-4781(92)90513-Y · doi:10.1016/0167-4781(92)90513-y
  38. Kim, 1995, Structural basis for the biological activities of bovine seminal ribonuclease, J Biol. Chem., 270, 10525, 10.1074/jbc.270.18.10525 · DOI
  39. Kleywegt, 1994, Detection, delineation, measurement and display of cavities in macromolecular structures, Acta Crystallog. sect. D, 50, 178, 10.1107/S0907444993011333 · DOI · Paper page
  40. Kobe, 1993, Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats, Nature, 366, 751, 10.1038/366751a0 · DOI · Paper page
  41. Kobe, 1993, Crystallization and preliminary X-ray analysis of porcine ribonuclease inhibitor, a protein with leucine-rich repeats, J Mol. Biol., 231, 137, 10.1006/jmbi.1993.1263 · DOI
  42. Kobe, 1994, The leucine-rich repeat: a versatile binding motif, Trends Biochem. Sci., 19, 415, 10.1016/0968-0004(94)90090-6 · DOI · Paper page
  43. Kobe, 1995, Proteins with leucine-rich repeats, Curr. Opin. Struct. Biol., 5, 409, 10.1016/0959-440X(95)80105-7 · DOI · Paper page
  44. Kobe, 1995, A structural basis of the interactions between leucine-rich repeats and protein ligands, Nature, 374, 183, 10.1038/374183a0 · DOI · Paper page
  45. Kobe, 1994, Complex between bovine ribonuclease A and porcine ribonuclease inhibitor crystallizes in a similar unit cell as free ribonuclease inhibitor, J Mol. Biol., 241, 288, 10.1006/jmbi.1994.1502 · doi:10.1006/jmbi.1994.1502
  46. Kraulis, 1991, MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures, J Appl. Crystallog., 24, 946, 10.1107/S0021889891004399 · DOI · Paper page
  47. Laskowski, 1980, Protein inhibitors of proteinases, Annu. Rev. Biochem., 49, 593, 10.1146/annurev.bi.49.070180.003113 · DOI · Paper page
  48. Lawrence, 1993, Shape complementarity at protein/protein interfaces, J Mol. Biol., 234, 946, 10.1006/jmbi.1993.1648 · DOI · Paper page
  49. Lee, 1989, Binding of placental ribonuclease inhibitor to the active site of angio-genin, Biochemistry, 28, 3556, 10.1021/bi00434a061 · DOI
  50. Lee, 1990, Kinetic characterization of two active mutants of placental ribonuclease inhibitor that lack internal repeats, Biochemistry, 29, 6633, 10.1021/bi00480a012 · doi:10.1021/bi00480a012
  51. Lee, 1990, Modular mutagenesis of human placental ribonuclease inhibitor, a protein with leucine-rich repeats, Proc. Natl Acad. Sci USA, 87, 1879, 10.1073/pnas.87.5.1879 · doi:10.1073/pnas.87.5.1879
  52. Lee, 1993, Structure and action of mammalian ribonuclease (angiogenin) inhibitor, Prog. Nud Acid Res. Mol. Biol., 44, 1, 10.1016/S0079-6603(08)60215-9 · DOI
  53. Lee, 1988, Primary structure of human placental ribonuclease inhibitor, Biochemistry, 27, 8545, 10.1021/bi00423a007 · doi:10.1021/bi00423a007
  54. Lee, 1989, Tryptophan fluorescence as a probe of placental ribonuclease inhibitor binding to angiogenin, Biochemistry, 28, 219, 10.1021/bi00427a030 · DOI
  55. Lee, 1989, Tight-binding inhibition of angiogenin and ribonuclease A by placental ribonuclease inhibitor, Biochemistry, 28, 225, 10.1021/bi00427a031 · DOI · Paper page
  56. Luzzati, 1952, Traitements statistique des erreurs dans la determination des structures cristallines, Acta Crystallog., 5, 802, 10.1107/S0365110X52002161 · DOI · Paper page
  57. Miller, 1987, Interior and surface of monomeric proteins, J Mol. Biol., 196, 641, 10.1016/0022-2836(87)90038-6 · DOI · Paper page
  58. Moroianu, 1994, Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity, Proc. Natl Acad. Sci. USA, 91, 1677, 10.1073/pnas.91.5.1677 · DOI · Paper page
  59. Mosimann, 1994, Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity, J Mol. Biol., 236, 1141, 10.1016/0022-2836(94)90017-5 · DOI
  60. Murthy, 1992, Sensitivity of monomeric and dimeric forms of bovine seminal ribonuclease to human placental ribonuclease inhibitor, Biochem. J., 281, 343, 10.1042/bj2810343 · doi:10.1042/bj2810343
  61. Nachman, 1990, Crystal structure of two covalent nucleoside derivatives of ribonuclease A, Biochemistry, 29, 928, 10.1021/bi00456a012 · DOI
  62. Nagano, 1976, Purification and properties of an alkaline ribonuclease from hepatic cytosol fraction of bullfrog, Rana catesbeiana, J. Biochem., 80, 19, 10.1093/oxfordjournals.jbchem.a131251 · doi:10.1093/oxfordjournals.jbchem.a131251
  63. Neumann, 1993, Interaction of semisynthetic variants of RNase A with ribonuclease inhibitor, Protein Sci., 3, 248, 10.1002/pro.5560030209 · doi:10.1002/pro.5560030209
  64. Nicholls, 1991, Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons, Proteins: Struct. Funct Genet., 11, 281, 10.1002/prot.340110407 · DOI · Paper page
  65. Nitta, 1993, Ribonuclease activity of sialic acid-binding lectin from Rana catesbeiana eggs, Glycobiology, 3, 37, 10.1093/glycob/3.1.37 · doi:10.1093/glycob/3.1.37
  66. Patthy, 1991, Modular exchange principles in proteins, Curr. Opin. Struct. Biol., 1, 351, 10.1016/0959-440X(91)90033-P · DOI · Paper page
  67. Polakowski, 1993, A ribonuclease inhibitor expresses anti-angiogenic properties and leads to reduced tumor growth in mice, Am. J. Pathol., 143, 507
  68. Powell, 1977, Restart procedures for the conjugate gradient method, Math. Prog., 12, 241, 10.1007/BF01593790 · DOI · Paper page
  69. Read, 1986, Improved Fourier coefficients for maps using phases from partial structures with errors, Acta Crystallog. sect. A, 42, 140, 10.1107/S0108767386099622 · DOI · Paper page
  70. Roth, 1958, Ribonuclease VII. Partial purification and characterization of a ribonuclease inhibitor in rat liver supernatant fraction, J. Biol. Chem., 231, 1085, 10.1016/S0021-9258(18)70468-7 · DOI · Paper page
  71. Roth, 1962, Ribonuclease IX. Further studies on ribonuclease inhibitor, Biochim. Biophys. Acta, 61, 903
  72. Schneider, 1988, The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module, EMBO J., 7, 4151, 10.1002/j.1460-2075.1988.tb03310.x · doi:10.1002/j.1460-2075.1988.tb03310.x
  73. Schreiber, 1993, Interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering, Biochemistry, 32, 5145, 10.1021/bi00070a025 · DOI · Paper page
  74. Shapiro, 1991, Interaction of human placental ribonuclease with placental ribonuclease inhibitor, Biochemistry, 30, 2246, 10.1021/bi00222a030 · doi:10.1021/bi00222a030
  75. Shapiro, 1992, Identification of functional arginines in human angiogenin by site-directed mutagenesis, Biochemistry, 31, 12477, 10.1021/bi00164a026 · DOI
  76. Shapiro, 1986, Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity, Biochemistry, 25, 7255, 10.1021/bi00371a002 · doi:10.1021/bi00371a002
  77. Shapiro, 1995, LRRning the Rite of springs, Nature Struct. Biol., 2, 350, 10.1038/nsb0595-350 · doi:10.1038/nsb0595-350
  78. Shortman, 1962, Studies on cellular inhibitors of ribonuclease. III. The levels of ribonuclease inhibitor during the regeneration of rat liver, Biochim. Biophys. Acta, 61, 50
  79. Strynadka, 1996, A potent new mode of p-lactamase inhibition revealed by the 1.7 A X-ray crystallo-graphic structure of the TEM-1-BLIP complex, Nature Struct. Biol., 3, 290, 10.1038/nsb0396-290 · DOI
  80. Vicentini, 1990, Protein chemical and kinetic characterization of recombinant porcine ribonuclease inhibitor expressed in Saccharomyces cerevisiae, Biochemistry, 29, 8827, 10.1021/bi00489a046 · doi:10.1021/bi00489a046
  81. Williams, 1988, The immunoglob-ulin superfamily-domains for cell surface recognition, Annu. Rev. Immunol., 6, 381, 10.1146/annurev.iy.06.040188.002121 · doi:10.1146/annurev.iy.06.040188.002121 · Paper page
  82. Wlodawer, 1988, Structure of phosphate-free ribonuclease A refined at 1.26 A, Biochemistry, 27, 2705, 10.1021/bi00408a010 · DOI · Paper page
  83. Wu, 1993, A cytotoxic ribonuclease, J. Biol. Chem., 268, 10686, 10.1016/S0021-9258(18)82252-9 · doi:10.1016/s0021-9258(18)82252-9
  84. Zegers, 1994, The structure of RNase A complexed with 3′-CMP and d(CpA): active site conformation and conserved water molecules, Protein Sci, 3, 2322, 10.1002/pro.5560031217 · doi:10.1002/pro.5560031217

Cited by

See all 213

Metadata

Authors
Kobe, B., & Deisenhofer, J.
Venue
Journal of Molecular Biology
Publisher
Elsevier BV
Published
1996-12
Volume
264
Issue
5
Pages
1028-1043
ISSN
0022-2836 (ISSN-L)
DOI
10.1006/jmbi.1996.0694
OpenAlex
W2007949653
Cited by
213
References
1
FWCI
1.24
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Mechanism of Ribonuclease Inhibition by Ribonuclease Inhibitor Protein Based on the Crystal Structure of its Complex with Ribonuclease A. https://app.cochat.ai/papers/10.1006/jmbi.1996.0694
The paper
Kobe, B., & Deisenhofer, J. (1996). Mechanism of Ribonuclease Inhibition by Ribonuclease Inhibitor Protein Based on the Crystal Structure of its Complex with Ribonuclease A. Journal of Molecular Biology. https://doi.org/10.1006/jmbi.1996.0694

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.