The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Extracellular and Intracellular Actions of Sphingosine-1-Phosphate
Open accessAbstract
Sphingosine-1-phosphate (S1P) is a bioactive lipid mediator with crucial roles in a wide variety of cellular functions across a broad range of organisms. Though a simple molecule in structure, S1P functions are complex. The formation of S1P is catalyzed by one of two sphingosine kinases that have differential cellular distributions as well as both overlapping and opposing functions and which are activated by many different stimuli. S1P can act on a family of G protein-coupled receptors (S1PRs) that are also differentially expressed in different cell types, which influences the cellular responses to S1P. In addition to acting on receptors located on the plasma membrane, S1P can also function inside the cell, independently of S1PRs. It also appears that both the intracellular location and the isotype of sphingosine kinase involved are major determinants of inside-out signaling of S1P in response to many extracellular stimuli. This chapter is focused on the current literature on extracellular and intracellular actions of S1P
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Cites
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., Brinkmann, V., Allende, M. L., Proia, R. L., & Cyster, J. G. (2004) · Nature · doi:10.1038/nature02284 · Cited by 2,581
Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
Cyster, J. G. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115628 · Cited by 856
Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases
Billich, A., Bornancin, F., Dévay, P., Mechtcheriakova, D., Urtz, N., & Baumruker, T. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m307687200 · Cited by 433
Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis
Igarashi, N., Okada, T., Hayashi, S., Fujita, T., Jahangeer, S., & Nakamura, S.-I. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306577200 · Cited by 415
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells
Mitra, P., Oskeritzian, C. A., Payne, S. G., Beaven, M. A., Milstien, S., & Spiegel, S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603734103 · Cited by 407
Self-citationSanna, M. G., Wang, S.-K., Gonzalez-Cabrera, P. J., Don, A., Marsolais, D., Matheu, M. P., Wei, S. H., Parker, I., Jo, E., Cheng, W.-C., et al. (2006) · Nature Chemical Biology · doi:10.1038/nchembio804 · Cited by 406
Okada, T., Ding, G., Sonoda, H., Kajimoto, T., Haga, Y., Khosrowbeygi, A., Gao, S., Miwa, N., Jahangeer, S., & Nakamura, S.-I. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m504507200 · Cited by 168
Cited by
Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics
Merrill, A. H. (2011) · Chemical Reviews · doi:10.1021/cr2002917 · Cited by 785
Conjugated Bile Acids Activate the Sphingosine–1–Phosphate Receptor 2 in Primary Rodent Hepatocytes
Studer, E., Zhou, X., Zhao, R., Wang, Y., Takabe, K., Nagahashi, M., Pandak, W. M., Dent, P., Spiegel, S., Shi, R., et al. (2012) · Hepatology · doi:10.1002/hep.24681 · Cited by 320
Self-citationParham, K. A., Zebol, J. R., Tooley, K. L., Sun, W. Y., Moldenhauer, L. M., Cockshell, M. P., Gliddon, B. L., Moretti, P. A., Tigyi, G., Pitson, S. M., et al. (2015) · The FASEB Journal · doi:10.1096/fj.14-261289 · Cited by 89
Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential
Meshcheryakova, A., Mechtcheriakova, D., & Pietschmann, P. (2017) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1332180 · Cited by 74
Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy
Nguyen-Tran, D.-H., Hait, N. C., Sperber, H., Qi, J., Fischer, K., Ieronimakis, N., Pantoja, M., Hays, A., Allegood, J., Reyes, M., et al. (2013) · Disease Models & Mechanisms · doi:10.1242/dmm.013631 · Cited by 58
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Metadata
- Authors
- Strub, G. M., Maceyka, M., Hait, N. C., Milstien, S., & Spiegel, S.
- Venue
- Advances in Experimental Medicine and Biology
- Publisher
- Springer New York
- Published
- 2010
- Volume
- 688
- Pages
- 141-155
- ISSN
- 0065-2598 (ISSN-L)
- OpenAlex
- W1499705597
- Cited by
- 355
- References
- 7
- FWCI
- 38.82
- Type
- book chapter
- Language
- en
- Open access
- green
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- Strub, G. M., Maceyka, M., Hait, N. C., Milstien, S., & Spiegel, S. (2010). Extracellular and Intracellular Actions of Sphingosine-1-Phosphate. Advances in Experimental Medicine and Biology. https://doi.org/10.1007/978-1-4419-6741-1_10
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