Autophagy in the Retina: A Potential Role in Age-Related Macular Degeneration

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A Role for Ubiquitin in Selective Autophagy

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The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy

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Oxidative Stress and Autophagy

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Autophagy and aging: keeping that old broom working

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Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa

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A block of autophagy in lysosomal storage disorders

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Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

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Mechanisms of acute axonal degeneration in the optic nerve in vivo

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Necroptosis, a novel form of caspase‐independent cell death, contributes to neuronal damage in a retinal ischemia‐reperfusion injury model

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Inhibition of the ATP‐driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2‐E may contribute to the pathogenesis of age‐related macular degeneration

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Autophagosome-Lysosome Fusion Depends on the pH in Acidic Compartments in CHO Cells

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Autophagy for tissue homeostasis and neuroprotection

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Apoptosis and Autophagy in Photoreceptors Exposed to Oxidative Stress

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Sequestosome 1/p62 – More than just a scaffold

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Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells

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Restoration of Lysosomal pH in RPE Cells from Cultured Human and ABCA4 −/− Mice: Pharmacologic Approaches and Functional Recovery

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TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease

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Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy‐mediated proteolysis in human retinal pigment epithelial cells

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Heat shock proteins as gatekeepers of proteolytic pathways—Implications for age-related macular degeneration (AMD)

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The Importance of Mitochondria in Age-Related and Inherited Eye Disorders

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Activation of autophagy in retinal ganglion cells

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Where do they come from? Insights into autophagosome formation

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p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.

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ARPE-19 retinal pigment epitheliaL CELLS are highly resistant to oxidative stress and exercise strict control over their lysosomal redox-active iron

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Using LC3 to monitor autophagy flux in the retinal pigment epithelium

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Lipofuscin granules in human photoreceptor cells.

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Autofluorescent inclusions in long-term postconfluent cultures of retinal pigment epithelium.

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Autophagy – hot topic in AMD

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Macroautophagy: a mechanism for mediating cell death or for promoting cell survival?

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The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retina.

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Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy

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Mechanisms of Age-Related Macular Degeneration

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Consequences of oxidative stress in age-related macular degeneration

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Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

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DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells—Implications for age-related macular degeneration (AMD)

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Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

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Autophagy in Age-Related Macular Degeneration: A Regulatory Mechanism of Oxidative Stress

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Autophagy and mitophagy in age-related macular degeneration: Custodians of retinal longevity

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