Redox Regulation of Ap-1

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

Angel, P. E., Imagawa, M., Chiu, R., Stein, B., Imbra, R. J., Rahmsdorf, H. J., Jonat, C., Herrlich, P. A., & Karin, M. (1987) · Cell · doi:10.1016/0092-8674(87)90611-8 · Cited by 2,930 · see citing works

Oncogenes and signal transduction

Cantley, L. C., Auger, K. R., Carpenter, C. F., Duckworth, B. C., Graziani, A., Kapeller, R., & Soltoff, S. P. (1991) · Cell · doi:10.1016/0092-8674(91)90639-g · Cited by 2,697 · see citing works

Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun.

Morgan, J., & Curran, T. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.002225 · Cited by 2,689 · see citing works

Oxygen radicals and human disease

CROSS, C. E., HALLIWELL, B., BORISH, E. T., PRYOR, W. A., AMES, B. N., SAUL, R. L., McCORD, J. M., & HARMAN, D. (1987) · Annals of Internal Medicine · doi:10.7326/0003-4819-107-4-526 · Cited by 1,856 · see citing works

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

Abate, C., Patel, L., Rauscher, F. J., & Curran, T. (1990) · Science · doi:10.1126/science.2118682 · Cited by 1,573 · see citing works

Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction

Yang-Yen, H.-F., Chambard, J.-C., Sun, Y.-L., Smeal, T., Schmidt, T. J., Drouin, J., & Karin, M. (1990) · Cell · doi:10.1016/0092-8674(90)90396-v · Cited by 1,553 · see citing works

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

Jonat, C., Rahmsdorf, H. J., Park, K.-K., Cato, A. C. B., Gebel, S., Ponta, H., & Herrlich, P. (1990) · Cell · doi:10.1016/0092-8674(90)90395-u · Cited by 1,544 · see citing works

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

Hai, T., & Curran, T. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.9.3720 · Cited by 1,321 · see citing works

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

Diamond, M. I., Miner, J. N., Yoshinaga, S. K., & Yamamoto, K. R. (1990) · Science · doi:10.1126/science.2119054 · Cited by 1,274 · see citing works

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

Schüle, R., Rangarajan, P. N., Kliewer, S. A., Ransone, L. J., Bolado, J., Yang, N., Verma, I. M., & Evans, R. M. (1990) · Cell · doi:10.1016/0092-8674(90)90397-w · Cited by 1,204 · see citing works

Current opinion in structural biology

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Redox activation of Fos‐Jun DNA binding activity is mediated by a DNA repair enzyme.

Xanthoudakis, S., Miao, G. G., Wang, F., Pan, Y., & Curran, T. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05411.x · Cited by 913 · see citing works

Cooperation between oncogenes

Hunter, T. R. (1991) · Cell · doi:10.1016/0092-8674(91)90637-e · Cited by 757 · see citing works

Identification and characterization of Ref‐1, a nuclear protein that facilitates AP‐1 DNA‐binding activity.

Xanthoudakis, S., & Curran, T. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05097.x · Cited by 708 · see citing works

Rapid and Preferential Activation of the c- jun Gene during the Mammalian UV Response

Devary, Y., Gottlieb, R. A., Lau, L. F., & Karin, M. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.5.2804 · Cited by 667 · see citing works

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

Rp, R., & Bravo, R. (1991) · PubMed · Cited by 539 · see citing works

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

Demple, B., Herman, T., & Chen, D. S. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.24.11450 · Cited by 538 · see citing works

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

Stein, B., Rahmsdorf, H. J., Steffen, A., Litfin, M., & Herrlich, P. A. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.11.5169 · Cited by 524 · see citing works

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

Gaub, M., Gross-Bellard, M., Scheuer, I., Chambon, P., & Sassone‐Corsi, P. (1990) · Cell · doi:10.1016/0092-8674(90)90422-b · Cited by 467 · see citing works

Avian sarcoma virus 17 carries the jun oncogene.

Maki, Y., Bos, T. J., Davis, C., Starbuck, M. W., & Vogt, P. K. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.9.2848 · Cited by 440 · see citing works

The enzymology of apurinic/apyrimidinic endonucleases

Doetsch, P. W., & Cunningham, R. P. (1990) · Mutation Research/DNA Repair · doi:10.1016/0921-8777(90)90004-o · Cited by 378 · see citing works

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains.

Xanthoudakis, S., Miao, G. G., & Curran, T. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.1.23 · Cited by 355 · see citing works

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

Chiu, R., Imagawa, M., Imbra, R. J., Bockoven, J. R., & Karin, M. (1987) · Nature · doi:10.1038/329648a0 · Cited by 352 · see citing works

Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

Robson, C. N., & Hickson, I. D. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.20.5519 · Cited by 305 · see citing works

Fos-Jun heterodimers and jun homodimers bend DNA in opposite orientations: Implications for transcription factor cooperativity

Kerppola, T. K., & Curran, T. (1991) · Cell · doi:10.1016/0092-8674(91)90621-5 · Cited by 305 · see citing works

Identification of Residues in the Human DNA Repair Enzyme HAP1 (Ref-1) That are Essential for Redox Regulation of Jun DNA Binding

Walker, L. J., Robson, C. N., Black, E., Gillespie, D. A., & Hickson, I. D. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.9.5370 · Cited by 275 · see citing works

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

Abate, C., Luk, D. C., Gentz, R., Rauscher, F. J., & Curran, T. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.3.1032 · Cited by 233 · see citing works

Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.

Owen, T. A., Bortell, R., Yocum, S. A., Smock, S. L., Zhang, M., Abate, C., Shalhoub, V., D, N. A. M., Wright, K. L., & van Wijnen, A. J. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.24.9990 · Cited by 204 · see citing works

Maf and Nrl can bind to AP-1 sites and form heterodimers with Fos and Jun.

Kerppola, T. K., & Curran, T. (1994) · PubMed · Cited by 193 · see citing works

Altered protein conformation on DNA binding by Fos and Jun

Patel, L., Abate, C., & Curran, T. (1990) · Nature · doi:10.1038/347572a0 · Cited by 192 · see citing works

DNA Bending by Fos and Jun: The Flexible Hinge Model

Kerppola, T. K., & Curran, T. (1991) · Science · doi:10.1126/science.1957173 · Cited by 187 · see citing works

Response to adversity: molecular control of gene activation following genotoxic stress.

Nj, H., & Fornace, A. J. (1991) · PubMed · Cited by 184 · see citing works

The Oncogene Handbook

Reddy, E. P., Skalka, A. M., & Curran, T. (1988) · Medical Entomology and Zoology · Cited by 178 · see citing works

The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor.Preprint

Perkins, K. K., Admon, A., Patel, N. H., & Tjian, R. (1990) · Genes & Development · doi:10.1101/gad.4.5.822 · Cited by 131 · see citing works

cDNA cloning, sequencing, expression and possible domain structure of human APEX nuclease homologous to Escherichia coli exonuclease III

Seki, S., Hatsushika, M., Watanabe, S., Akiyama, K., Nagao, K., & Tsutsui, K. (1992) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/0167-4781(92)90027-w · Cited by 122 · see citing works

Escape from redox regulation enhances the transforming activity of Fos.

Okuno, H., Akahori, A., Sato, H., Xanthoudakis, S., Curran, T., & Iba, H. (1993) · PubMed · Cited by 122 · see citing works

Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damagein vitro: homology with bacterial repair enzymes

Robson, C. N., Milne, A., Pappin, D., & Hickson, I. D. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.5.1087 · Cited by 118 · see citing works

Nucleotide sequence of the xth gene of Escherichia coli K-12

Saporito-Irwin, S. M., Smith-White, B. J., & Cunningham, R. P. (1988) · Journal of Bacteriology · doi:10.1128/jb.170.10.4542-4547.1988 · Cited by 79 · see citing works

Drosophila Rrp1 protein: an apurinic endonuclease with homologous recombination activities.

Sander, M., Lowenhaupt, K., & Rich, A. S. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.15.6780 · Cited by 64 · see citing works

Structure of the human DNA repair geneHAP1and its localisation to chromosome 14q 11.2–12

Robson, C. N., Hochhauser, D., Craig, R., et al. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.17.4417 · Cited by 62 · see citing works

The exoA gene of Streptococcus pneumoniae and its product, a DNA exonuclease with apurinic endonuclease activity

Puyet, A., Greenberg, B., & Lacks, S. A. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.5.2278-2286.1989 · Cited by 52 · see citing works

Amino acid substitutions modulate the effect of Jun on transformation, transcriptional activation and DNA replication.

Morgan, I. M., Asano, M., Håvarstein, L. S., et al. (1993) · PubMed · Cited by 22 · see citing works

Oxidative Stress in COPD

Kirkham, P. A., & Barnes, P. J. (2013) · Chest · doi:10.1378/chest.12-2664 · Cited by 685 · see citing works

Intracellular iron transport and storage: from molecular mechanisms to health implications

Mackenzie, E. L., Iwasaki, K., & Tsuji, Y. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1893 · Cited by 526 · see citing works

Base excision repair and cancer

Wallace, S. S., Murphy, D. L., & Sweasy, J. B. (2012) · Cancer Letters · doi:10.1016/j.canlet.2011.12.038 · Cited by 329 · see citing works

Roles of UVA radiation and DNA damage responses in melanoma pathogenesis

Khan, A. Q., Travers, J. B., & Kemp, M. G. (2018) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22176 · Cited by 152 · see citing works

JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress

Tsuji, Y. (2005) · Oncogene · doi:10.1038/sj.onc.1208901 · Cited by 121 · see citing works

Hemin-Mediated Regulation of an Antioxidant-Responsive Element of the Human Ferritin H Gene and Role of Ref-1 during Erythroid Differentiation of K562 Cells

Iwasaki, K., MacKenzie, E. L., Hailemariam, K., Sakamoto, K., & Tsuji, Y. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.7.2845-2856.2006 · Cited by 112 · see citing works

Nonenzymatic release of N7-methylguanine channels repair of abasic sites into an AP endonuclease-independent pathway in Arabidopsis

García-Gil, C. M. B., Córdoba‐Cañero, D., Ariza, R. R., & Roldán‐Arjona, T. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1719497115 · Cited by 19 · see citing works

Multifunctional human apurinic/apyrimidinic endonuclease 1: Role of additional functions

Dyrkheeva, N. S., Khodyreva, S. N., & Lavrik, O. I. (2007) · Molecular Biology · doi:10.1134/s0026893307030065 · Cited by 30 · see citing works

Apurinic/Apyrimindinic Endonuclease in Redox Regulation and Oxidative Stress

Georgiadis, M. M. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-384999-1.10011-3

The splicing component ISY1 regulates APE1 in base excision repair

Jaiswal, A. S., Williamson, E. A., Srinivasan, G., Kong, K. Y., Lomelino, C. L., McKENNA, R. V., Walter, C. A., Sung, P., Narayan, S., & Hromas, R. (2019) · DNA repair · doi:10.1016/j.dnarep.2019.102769 · Cited by 20 · see citing works

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions

Vidal, A. E., Boiteux, S., Hickson, I. D., & Radicella, J. P. (2001) · The EMBO Journal · doi:10.1093/emboj/20.22.6530 · Cited by 459 · see citing works