Cannabinoid-Based Medicines: Dosing, Titration & Monitoring

The PHQ-9: Validity of a brief depression severity measure

Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works

A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7

Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765 · see citing works

Validation of the Brief Pain Inventory for chronic nonmalignant pain

Tan, G., Jensen, M. P., Thornby, J. I., & Shanti, B. F. (2004) · The Journal of Pain · doi:10.1016/j.jpain.2003.12.005 · Cited by 1,416 · see citing works

Human Cannabinoid Pharmacokinetics

Huestis, M. A. (2007) · Chemistry & Biodiversity · doi:10.1002/cbdv.200790152 · Cited by 1,102 · see citing works

Practical considerations in medical cannabis administration and dosing

MacCallum, C. A., & Russo, E. B. (2018) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2018.01.004 · Cited by 663 · see citing works

Routes of administration for cannabis use – basic prevalence and related health outcomes: A scoping review and synthesis

Russell, C., Rueda, S., Room, R., TYNDALL, M. W., & Fischer, B. (2017) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2017.11.008 · Cited by 300 · see citing works

Vaporization as a Smokeless Cannabis Delivery System: A Pilot Study

Abrams, D. I., Vizoso, H., Shade, S., Jay, C., Kelly, M., & Benowitz, N. (2007) · Clinical pharmacology and therapy · doi:10.1038/sj.clpt.6100200 · Cited by 263 · see citing works

Plasma Cannabinoid Pharmacokinetics following Controlled Oral Δ9-Tetrahydrocannabinol and Oromucosal Cannabis Extract Administration

Karschner, E. L., Darwin, W. D., Goodwin, R. S., Wright, S., & Huestis, M. A. (2010) · Clinical Chemistry · doi:10.1373/clinchem.2010.152439 · Cited by 231 · see citing works

Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines.

Zgair, A., Wong, J. C. M., Lee, J. B., Mistry, J., Sivak, O., Wasan, K. M., Hennig, I. M., Barrett, D. A., Constantinescu, C. S., Fischer, P. M., et al. (2016) · Europe PMC (PubMed Central) · Cited by 130 · see citing works

Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs.

Bartner, L. R., McGrath, S., Rao, S., Hyatt, L. K., & Wittenburg, L. A. (2018) · Europe PMC (PubMed Central) · Cited by 130 · see citing works

Communicating THC levels and ‘dose’ to consumers: Implications for product labelling and packaging of cannabis products in regulated markets

Hammond, D. G. (2019) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2019.07.004 · Cited by 106 · see citing works

Two cases of "cannabis acute psychosis" following the administration of oral cannabis

Favrat, B., Ménétrey, A., Augsburger, M. P., Rothuizen, L. E., Appenzeller, M., Buclin, T., Pin, M. A., Mangin, P. J., & Giroud, C. (2005) · BMC Psychiatry · doi:10.1186/1471-244x-5-17 · Cited by 100 · see citing works

Medical cannabis ‒ the Canadian perspective

Ramkellawan, S., Bober, S., Mindra, S., Moreau, J. M., & Ko, G. D. (2016) · Journal of Pain Research · doi:10.2147/jpr.s98182 · Cited by 91 · see citing works

Cannabis Use, Lung Cancer, and Related Issues

Jett, J. R., Stone, E. C. A., Warren, G. W., & Cummings, K. M. (2018) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2017.12.013 · Cited by 73 · see citing works

Topical Medical Cannabis: A New Treatment for Wound Pain—Three Cases of Pyoderma Gangrenosum

Maida, V., & Corban, J. P. A. H. (2017) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2017.06.005 · Cited by 66 · see citing works

A Multiple‐Dose, Randomized, Double‐Blind, Placebo‐Controlled, Parallel‐Group QT/QTc Study to Evaluate the Electrophysiologic Effects of THC/CBD Spray

Sellers, E. M., Schoedel, K. A., Bartlett, C., Romach, M. K., Russo, E. B., Stott, C. G., Wright, S., White, L., Duncombe, P., & Chen, C. (2013) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.36 · Cited by 57 · see citing works

Temperature Stability and Bioadhesive Properties of Δ9-Tetrahydrocannabinol Incorporated Hydroxypropylcellulose Polymer Matrix Systems

Repka, M. A., Munjal, M. K., ElSohly, M. A., & Ross, S. A. (2006) · Drug Development and Industrial Pharmacy · doi:10.1080/03639040500387914 · Cited by 57 · see citing works

The effectiveness of self-directed medical cannabis treatment for pain

Li, X., Vigil, J. M., Stith, S. S., Brockelman, F., Keeling, K., & Hall, B. (2019) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.07.022 · Cited by 45 · see citing works

Pharmacokinetics of THC in Inhaled and Oral Preparations

Huestis, M. A. (1999) · Humana Press eBooks · doi:10.1007/978-1-59259-710-9_11 · Cited by 28 · see citing works

The development of Sativex® — a natural cannabis-based medicine

Guy, G. W., & Stott, C. G. (2005) · Birkhäuser Basel eBooks · doi:10.1007/3-7643-7358-x_14 · Cited by 28 · see citing works

Priming primary care providers to engage in evidence-based discussions about cannabis with patients

Kansagara, D. L., Becker, W. C., Ayers, C. K., & Tetrault, J. M. (2019) · Addiction Science & Clinical Practice · doi:10.1186/s13722-019-0171-3 · Cited by 19 · see citing works

Cannabis treatment in hospitalized patients using the SYQE inhaler: Results of a pilot open-label study

Vulfsons, S., Ognitz, M., Bar‐Sela, G., Raz‐Pasteur, A., & Eisenberg, E. (2019) · Palliative & Supportive Care · doi:10.1017/s147895151900021x · Cited by 17 · see citing works

Cannabinoids and Pain Control in the Periphery

McDougall, J. J. (2009) · Wiley eBooks · doi:10.1002/9780470522226.ch13 · Cited by 9 · see citing works

Moving forwards with the standard THC unit

Freeman, T. P., & Lorenzetti, V. (2020) · Addiction · doi:10.1111/add.15107 · Cited by 8 · see citing works

Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions

Bell, A. D., MacCallum, C., Margolese, S., Walsh, Z., Wright, P., Daeninck, P. J., Mandarino, E., Lacasse, G., Kaur Deol, J., de Freitas, L., et al. (2024) · Cannabis & Cannabinoid Research · doi:10.1089/can.2021.0156 · Cited by 78 · see citing works

“Is medical cannabis safe for my patients?” A practical review of cannabis safety considerations

MacCallum, C. A., Lo, L. A., & Boivin, M. (2021) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2021.05.002 · Cited by 71 · see citing works

Clinical Application of Cannabis Vaporization: Examining Safety and Best Practices

MacCallum, C. A., Lo, L. A., & Boivin, M. (2024) · Cannabis and Cannabinoid Research · doi:10.1089/can.2023.0219 · Cited by 4 · see citing works

Practical Matters: Cannabis Formulations and Dosing

Sera, L., & Hempel‐Sanderoff, C. (2025) · Springer eBooks · doi:10.1007/978-3-031-80352-9_8

Practical considerations in medical cannabis administration and dosing

MacCallum, C. A., & Russo, E. B. (2018) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2018.01.004 · Cited by 663 · see citing works

Choosing a Product, Route of Administration, Initial Dosage, Titration, Monitoring and Management of Adverse Effects

Schecter, D., & Cyr, C. (2022) · Springer eBooks · doi:10.1007/978-3-030-89918-9_7 · Cited by 3 · see citing works

Delivery and Dosage of Cannabis Medicine

Malka, D. (2021) · CRC Press eBooks · doi:10.1201/9781003098201-17

Can we predict the treatment doses of THC and CBD and does it matter?

Halamish, N., Schleider, L. B., McGuire, S. F., & Novack, V. (2023) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2023.03.028 · Cited by 6 · see citing works