Stress Challenges and Immunity in Space: From Mechanisms to Monitoring and Preventive Strategies

Nutritional Countermeasures for Spaceflight-Related Stress

Heer, M. A., Baecker, N., Smith, S. M., & Swart, S. R. (2011) · Springer eBooks · doi:10.1007/978-3-642-22272-6_29 · Cited by 10 · see citing works

Immune System in Space: General Introduction and Observations on Stress-Sensitive Regulations

Crucian, B. E., & Choukèr, A. (2011) · Springer eBooks · doi:10.1007/978-3-642-22272-6_9 · Cited by 8 · see citing works

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions

Crucian, B. E., Choukèr, A., Simpson, R. J., Mehta, S., Marshall, G., Smith, S. M., Zwart, S. R., Heer, M., Ponomarev, S., Whitmire, A., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01437 · Cited by 421 · see citing works

The Impact of Everyday Stressors on the Immune System and Health

Seiler, A., Fagundes, C. P., & Christian, L. M. (2019) · Springer eBooks · doi:10.1007/978-3-030-16996-1_6 · Cited by 169 · see citing works

Future perspectives on space psychology: Recommendations on psychosocial and neurobehavioural aspects of human spaceflight

la Torre, G. G. D., van Baarsen, B., Ferlazzo, F., Kanas, N., Weiss, K., Schneider, S., & Whiteley, I. (2012) · Acta Astronautica · doi:10.1016/j.actaastro.2012.08.013 · Cited by 117 · see citing works

Space radiation effects on plant and mammalian cells

Arena, C., Micco, V. D., Macaeva, E., & Quintens, R. (2014) · Acta Astronautica · doi:10.1016/j.actaastro.2014.05.005 · Cited by 113 · see citing works

Increased core body temperature in astronauts during long-duration space missions

Stahn, A. C., Werner, A., Opatz, O., Maggioni, M. A., Steinach, M., von Ahlefeld, V. W., Moore, A., Crucian, B. E., Smith, S. M., Zwart, S. R., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-15560-w · Cited by 100 · see citing works

Terrestrial stress analogs for spaceflight associated immune system dysregulation

Crucian, B. E., Simpson, R. J., Mehta, S. K., Stowe, R., Choukèr, A., Hwang, S., Actor, J. K., Salam, A. P., Pierson, D. L., & Sams, C. F. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.01.011 · Cited by 98 · see citing works

The oxidative burst reaction in mammalian cells depends on gravity

Adrian, A., Schoppmann, K., Sromicki, J., Brungs, S., von der Wiesche, M., Hock, B., Kolanus, W., Hemmersbach, R., & Ullrich, O. (2013) · Cell Communication and Signaling · doi:10.1186/1478-811x-11-98 · Cited by 79 · see citing works

Towards human exploration of space: the THESEUS review series on cardiovascular, respiratory, and renal research priorities

AUBERT, A. E., Larina, I., Momken, I., Blanc, S., White, O., Prisk, G. K., & Linnarsson, D. (2016) · npj Microgravity · doi:10.1038/npjmgrav.2016.31 · Cited by 73 · see citing works

Three Weeks of Murine Hindlimb Unloading Induces Shifts from B to T and from Th to Tc Splenic Lymphocytes in Absence of Stress and Differentially Reduces Cell-Specific Mitogenic Responses

Gaignier, F., Schenten, V., Bittencourt, M. D. C., Gauquelin‐Koch, G., Frippiat, J., & Legrand-Frossi, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092664 · Cited by 71 · see citing works

Effects of parabolic flight and spaceflight on the endocannabinoid system in humans

Strewe, C., Feuerecker, M., Nichiporuk, I., Kaufmann, I., Hauer, D., Morukov, B., Schelling, G., & Choukèr, A. (2012) · Reviews in the Neurosciences · doi:10.1515/revneuro-2012-0057 · Cited by 63 · see citing works

Affective, Social, and Cognitive Outcomes During a 1-Year Wintering in Concordia

Nicolas, M., Suedfeld, P., Weiss, K., & Gaudino, M. (2015) · Environment and Behavior · doi:10.1177/0013916515583551 · Cited by 55 · see citing works

Surgery in space

Panesar, S. S., & Ashkan, K. (2018) · British journal of surgery · doi:10.1002/bjs.10908 · Cited by 53 · see citing works

Membrane technologies for space engineering

Bernardo, P., Iulianelli, A., Macedonio, F., & Drioli, E. (2021) · Journal of Membrane Science · doi:10.1016/j.memsci.2021.119177 · Cited by 48 · see citing works

The current state and future trends of space nutrition from a perspective of astronauts' physiology

Bychkov, A., Reshetnikova, P., Бычкова, Е. С., Подгорбунских, Е. М., & Koptev, V. Y. (2021) · International Journal of Gastronomy and Food Science · doi:10.1016/j.ijgfs.2021.100324 · Cited by 48 · see citing works

Host-Microbe Interactions in Microgravity: Assessment and Implications

Foster, J. S., Wheeler, R. M., & Pamphile, R. (2014) · Life · doi:10.3390/life4020250 · Cited by 45 · see citing works

Cardiac and Peripheral Autonomic Responses to Orthostatic Stress During Transcutaneous Vagus Nerve Stimulation in Healthy Subjects

Tobaldini, E., Toschi‐Dias, E., de Souza, L. A., Casali, K. R., Vicenzi, M., Sandrone, G., Cogliati, C. B., Rovere, M. T. L., Pinna, G. D., & Montano, N. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040496 · Cited by 44 · see citing works

Exercise as a countermeasure for latent viral reactivation during long duration space flight

Agha, N. H., Mehta, S. K., Rooney, B. V., Laughlin, M. S., Markofski, M. M., Pierson, D. L., Katsanis, E., Crucian, B. E., & Simpson, R. J. (2020) · The FASEB Journal · doi:10.1096/fj.201902327r · Cited by 43 · see citing works

Measurement fidelity of heart rate variability signal processing: The devil is in the details

Jarrin, D. C., McGrath, J. J., Giovanniello, S., Poirier, P., & Lambert, M. A. (2012) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2012.07.004 · Cited by 43 · see citing works

The perfect boring situation—Addressing the experience of monotony during crewed deep space missions through habitability design

Peldszus, R., Dalke, H., Pretlove, S., & Welch, C. (2013) · Acta Astronautica · doi:10.1016/j.actaastro.2013.04.024 · Cited by 42 · see citing works

Severe disruption of the cytoskeleton and immunologically relevant surface molecules in a human macrophageal cell line in microgravity—Results of an in vitro experiment on board of the Shenzhou-8 space mission

Paulsen, K., Tauber, S., Goelz, N., Simmet, D. M., Engeli, S., Birlem, M., Dumrese, C., Karer, A., Hunziker, S., Biskup, J., et al. (2013) · Acta Astronautica · doi:10.1016/j.actaastro.2013.06.007 · Cited by 39 · see citing works

Spaceflight alters host-gut microbiota interactions

González, E., Lee, M., Tierney, B. T., Lytell, N., Flores, P., Mishra, M., Beckett, L., Finkelstein, A., Mo, A., Walton, P., et al. (2024) · npj Biofilms and Microbiomes · doi:10.1038/s41522-024-00545-1 · Cited by 36 · see citing works

Transcriptional Profiling of the Probiotic Escherichia coli Nissle 1917 Strain under Simulated Microgravity

Yim, J., Cho, S. W., Kim, B., Park, S., Han, Y. H., & Seo, S. W. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082666 · Cited by 34 · see citing works

Reanalysis of the Mars500 experiment reveals common gut microbiome alterations in astronauts induced by long-duration confinement

Brereton, N. J. B., Pitre, F. E., & González, E. (2021) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2021.03.040 · Cited by 33 · see citing works

The Impact of Everyday Stressors on the Immune System and Health

Christian, L. M., & Glaser, R. (2011) · Springer eBooks · doi:10.1007/978-3-642-22272-6_4 · Cited by 25 · see citing works

Water and microbial monitoring technologies towards the near future space exploration

Amalfitano, S., Levantesi, C., Copetti, D., Stefani, F., Locantore, I., Guarnieri, V., Lobascio, C., Bersani, F., Giacosa, D., Detsis, E., et al. (2020) · Water Research · doi:10.1016/j.watres.2020.115787 · Cited by 23 · see citing works

Examining personal values in extreme environment contexts: Revisiting the question of generalizability

Smith, N., Sandal, G. M., Leon, G. R., & Kjærgaard, A. (2017) · Acta Astronautica · doi:10.1016/j.actaastro.2017.04.008 · Cited by 20 · see citing works

A Model of Chronic Exposure to Unpredictable Mild Socio-Environmental Stressors Replicates Some Spaceflight-Induced Immunological Changes

Gaignier, F., Legrand-Frossi, C., Stragier, E., Mathiot, J., Merlin, J., Cohen‐Salmon, C., Lanfumey, L., & Frippiat, J. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00514 · Cited by 20 · see citing works

A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression

Michalettou, T.-D., Michalopoulos, I., Costes, S., Hellweg, C., Hada, M., & Georgakilas, A. (2021) · Life · doi:10.3390/life11020115 · Cited by 14 · see citing works

Who will adapt best in Antarctica? Resilience as mediator between past experiences in Antarctica and present well-being

Zhang, Z., Yan, G.-G., Sun, C., & Saklofske, D. (2021) · Personality and Individual Differences · doi:10.1016/j.paid.2020.109963 · Cited by 14 · see citing works

Changes in the distribution and function of leukocytes after whole body iron ion irradiation

Gridley, D. S., & Pecaut, M. J. (2016) · Journal of Radiation Research · doi:10.1093/jrr/rrw051 · Cited by 13 · see citing works

Polysaccharide from Patinopecten yessoensis Skirt Boosts Immune Response via Modulation of Gut Microbiota and Short-Chain Fatty Acids Metabolism in Mice

Li, Y., Qin, J., Cheng, Y., Ai, Y., Han, Z., Li, M., Qi, Y., Zhao, Q., & Li, Z. (2021) · Foods · doi:10.3390/foods10102478 · Cited by 13 · see citing works

A cubesat centrifuge for long duration milligravity research

Asphaug, E. I., Thangavelautham, J., Klesh, A., Chandra, A., Nallapu, R. T., Raura, L., Herreras-Martinez, M., & Schwartz, S. R. (2017) · npj Microgravity · doi:10.1038/s41526-017-0021-0 · Cited by 10 · see citing works

Water Quality and Total Microbial Load: A Double-Threshold Identification Procedure Intended for Space Applications

Amalfitano, S., Levantesi, C., Garrelly, L., Giacosa, D., Bersani, F., & Rossetti, S. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02903 · Cited by 10 · see citing works

Immune Dysfunction in Spaceflight: An Integrative View

Yi, B., Crucian, B. E., Tauber, S., Ullrich, O., & Choukèr, A. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3277-1_3 · Cited by 7 · see citing works

Requirements for modeling airborne microbial contamination in space stations

Houdt, R. V., Kokkonen, E., Lehtimäki, M., Pasanen, P. O., Leys, N., & Kulmala, I. K. (2018) · Acta Astronautica · doi:10.1016/j.actaastro.2018.01.004 · Cited by 6 · see citing works

Impact of COVID-19 on Brain and Psychological Health, its Possible Mechanisms, and Coping Strategies

Simnani, F. Z., Singh, D., Choudhury, A., & Akhtar, A. (2022) · Recent Patents on Biotechnology · doi:10.2174/1872208316666220617110402 · Cited by 4 · see citing works

Circadian Rhythm and Stress

Steinach, M., & Gunga, H. (2019) · Springer eBooks · doi:10.1007/978-3-030-16996-1_9 · Cited by 3 · see citing works

Circadian Rhythm and Stress

Steinach, M., & Gunga, H. (2011) · Springer eBooks · doi:10.1007/978-3-642-22272-6_7 · Cited by 3 · see citing works

Highlights of Human Spaceflight in Europe: ESA and DLR

Ruyters, G. (2020) · Springer eBooks · doi:10.1007/978-3-319-10152-1_70-1 · Cited by 2 · see citing works

Lymphocyte Signaling and Function in Altered Physiological Environments

Mann, V., Okoro, E., Sodipe, A., Williams, C., Ngantcha, P., & Sundaresan, A. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.81171 · Cited by 2 · see citing works

Spaceflight and Medical Microbiology: Possible Implications for Standard Infection Diagnostics and Therapy

Boschert, A. L., Leuko, S., Krämer, C. L., Siems, K., Ly, Y.-T., & Arndt, F. (2025) · Life · doi:10.3390/life15111757 · Cited by 1 · see citing works

Use of In Vitro Cell Culture Models to Understand the Cellular and Molecular Basis of Immune Dysfunction During Spaceflight

Tauber, S., Yi, B., Choukèr, A., & Ullrich, O. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3277-1_6 · Cited by 1 · see citing works

The Immune System in Space and Space-Like Conditions: From the Human Study Perspective

Yi, B., & Choukèr, A. (2016) · SpringerBriefs in space life sciences · doi:10.1007/978-3-319-41466-9_3 · Cited by 1 · see citing works

Towards Human Exploration of Space:a EUropean Strategy - Roadmap

Worms, J.-C., Walter, N., White, O., Martinez-Schmitt, J., Marshall-Goebel, K. J., Blanc, S., Monken, I., Hockey, B., Reitz, G., Leys, N., et al. (2012) · elib (German Aerospace Center) · Cited by 1 · see citing works

The Exploration of an Effective Medical Countermeasure Enhancing Survival and Hematopoietic Recovery and Preventing Immune Insufficiency in Lethally-Irradiated Mice

Wu, T. (2020) · IUScholarWorks (Indiana University) · doi:10.7912/c2/2032

Psychological Concerns and Effects on Immune Responses amidst Covid-19 Pandemic

Ali, S., & Tariq, J. (2020) · Pakistan Journal of Public Health · doi:10.32413/pjph.v10i1.552

Effectiveness of jogging, eye movement exercises, and diaphragmatic breathing in patients with migraine: a randomized controlled trialPreprint

Rahimi, M. D., Alidoosti, F., Hassani, P., Ghasemi, M. M., & Fadardi, J. S. (2021) · Research Square · doi:10.21203/rs.3.rs-309380/v2

Highlights of Human Spaceflight in Europe: ESA and DLR

Ruyters, G. (2021) · Springer eBooks · doi:10.1007/978-3-319-12191-8_70

The effectiveness of counseling program to enhance the psychological

Shawahneh, A. A. (2022) · Journal of King Abdulaziz University Arts and Humanities · doi:10.4197/art.30-3.5

Alcances en neurociencias cognitivas: Fundamentación línea de investigación en neurociencias y neurodesarrollo

de Antioquia, U., Valencia, M., Delgado, L. A. C., Universidad, C. E. S., Noriega, I., Al‐Khalil, K., Trejos‐Castillo, E., O’Boyle, M. W., Villanueva-Bonilla, C., Surcolombiana, U., et al. (2023) · Editorial Universidad Santiago de Cali eBooks · doi:10.35985/9786287604421 · Cited by 4 · see citing works

Violencia familiar y su impacto en el funcionamiento neuropsicológico de niños, adolescentes y adultos

Javeriana, P. U., Mejía, Ó. M. A., Rodríguez, D. A. L., Javeriana, P. U., Martínez, A. M. M., & Javeriana, P. U. (2023) · Editorial Universidad Santiago de Cali eBooks · doi:10.35985/9786287604421.8

Crew health—Psychological, biological, and medical issues and the need for a systems approach

Shelhamer, M., & Fogarty, J. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-91280-8.00001-0

Adaptation et adaptabilité en situations extrêmes : évolution, association et rôle des facteurs psychologiques

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A Systematic Literature Review Exploring Intersectionality Between ACEs, Attachment, and Military PTSD

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Summary and Outlook

Moser, D., Choukèr, A., & authors..., F. A. (2019) · Springer eBooks · doi:10.1007/978-3-030-16996-1_40

Space as an extraordinary model of Stress research, the role of the ESA Topical Team

Choukèr, A. (2015) · Autonomic Neuroscience · doi:10.1016/j.autneu.2015.07.275

Considerations for Preventive and Therapeutic Strategies

Frippiat, J., Heer, M. A., & Choukèr, A. (2011) · Springer eBooks · doi:10.1007/978-3-642-22272-6_26

Stress and immunity

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Immune Dysfunction in Spaceflight: An Integrative View

Yi, B., Crucian, B. E., Tauber, S., Ullrich, O., & Choukèr, A. (2016) · Springer eBooks · doi:10.1007/978-1-4939-3277-1_3 · Cited by 7 · see citing works