Natural Products from Sponges

Marine natural products

Faulkner, D. J. (1990) · Natural Product Reports · doi:10.1039/np9900700269 · Cited by 4,880 · see citing works

Halichondrins-antitumor polyether macrolides from a marine sponge

Hirata, Y., & Uemura, D. (1986) · Pure and Applied Chemistry · doi:10.1351/pac198658050701 · Cited by 519 · see citing works

Marine natural products

Blunt, J. W., Copp, B. R., Keyzers, R. A., Munro, M. H. G., & Prinsep, M. R. (2012) · Natural Product Reports · doi:10.1039/c2np20112g · Cited by 518 · see citing works

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

Song, J., Rechkoblit, O., Bestor, T. H., & Patel, D. J. (2010) · Science · doi:10.1126/science.1195380 · Cited by 472 · see citing works

Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.

Mooberry, S. L., Tien, G., Hernandez, A. H., Plubrukarn, A., & Davidson, B. S. (1999) · PubMed · Cited by 330 · see citing works

Bioactive marine metabolites. Part 16. Calyculin A. A novel antitumor metabolite from the marine sponge Discodermia calyx

Kato, Y., Fusetani, N., Matsunaga, S., et al. (1986) · Journal of the American Chemical Society · doi:10.1021/ja00270a061 · Cited by 306 · see citing works

Cortistatins A, B, C, and D, Anti-angiogenic Steroidal Alkaloids, from the Marine Sponge Corticium simplex

Aoki, S., Watanabe, Y., Sanagawa, M., et al. (2006) · Journal of the American Chemical Society · doi:10.1021/ja057404h · Cited by 293 · see citing works

Phorboxazoles A and B: potent cytostatic macrolides from marine sponge Phorbas species

Searle, P. A., & Molinski, T. F. (1995) · Journal of the American Chemical Society · doi:10.1021/ja00136a009 · Cited by 289 · see citing works

Peloruside A: A Potent Cytotoxic Macrolide Isolated from the New Zealand Marine Sponge Mycale sp.

West, L. M., Northcote, P. T., & Battershill, C. N. (1999) · The Journal of Organic Chemistry · doi:10.1021/jo991296y · Cited by 258 · see citing works

Salicylihalamides A and B, Novel Cytotoxic Macrolides from the Marine Sponge Haliclona sp.

Erickson, K. L., Beutler, J. A., Cardellina, J. H., et al. (1997) · The Journal of Organic Chemistry · doi:10.1021/jo971556g · Cited by 255 · see citing works

Peloruside A, a novel antimitotic agent with paclitaxel-like microtubule- stabilizing activity.

Hood, K. A., West, L. M., Rouwé, B., Northcote, P. T., Berridge, M. V., Wakefield, S. J., & Miller, J. H. (2002) · PubMed · Cited by 254 · see citing works

Mycalamide A, an antiviral compound from a New Zealand sponge of the genus Mycale

Perry, N. B., Blunt, J. W., Munro, M. H. G., et al. (1988) · Journal of the American Chemical Society · doi:10.1021/ja00222a067 · Cited by 246 · see citing works

Laulimalides. New potent cytotoxic macrolides from a marine sponge and a nudibranch predator

Corley, D. G., Herb, R., Moore, R. E., et al. (1988) · The Journal of Organic Chemistry · doi:10.1021/jo00250a053 · Cited by 227 · see citing works

New Bisindole Alkaloids of the Topsentin and Hamacanthin Classes from the Mediterranean Marine Sponge Rhaphisia lacazei

Casapullo, A., Bifulco, G., Bruno, I., et al. (2000) · Journal of Natural Products · doi:10.1021/np9903292 · Cited by 219 · see citing works

Phase II Study of the Halichondrin B Analog Eribulin Mesylate in Patients With Locally Advanced or Metastatic Breast Cancer Previously Treated With an Anthracycline, a Taxane, and Capecitabine

Cortés, J., Vahdat, L. T., Blum, J. L., Twelves, C., Campone, M., Roche, H. H., Bachelot, T., Awada, A. H., Paridaens, R., Gonçalvès, A., et al. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2009.25.8467 · Cited by 214 · see citing works

Polytheonamides A and B, Highly Cytotoxic, Linear Polypeptides with Unprecedented Structural Features, from the Marine Sponge, Theonella s winhoei

Hamada, T., Matsunaga, S., Yano, G., et al. (2004) · Journal of the American Chemical Society · doi:10.1021/ja045749e · Cited by 211 · see citing works

Neopeltolide, a Macrolide from a Lithistid Sponge of the Family Neopeltidae

Wright, A. E., Botelho, J. C., Guzmán, E. A., et al. (2007) · Journal of Natural Products · doi:10.1021/np060597h · Cited by 198 · see citing works

Fijianolides, polyketide heterocycles from a marine sponge

Quiñoá, E., Kakou, Y., & Crews, P. (1988) · The Journal of Organic Chemistry · doi:10.1021/jo00250a052 · Cited by 195 · see citing works

Structure of swinholide-a, a new macrolide from the marine sponge

Carmeli, S., & Kashman, Y. (1985) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)61925-1 · Cited by 194 · see citing works

CONTRIBUTIONS TO THE STUDY OF MARINE PRODUCTS. XXXIX. THE NUCLEOSIDES OF SPONGES. III.¹ SPONGOTHYMIDINE AND SPONGOURIDINE²

BERGMANN, W., & BURKE, D. C. (1955) · The Journal of Organic Chemistry · doi:10.1021/jo01128a007 · Cited by 194 · see citing works

Antineoplastic agents. 219. Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp

Pettit, G. R., Herald, C. L., Boyd, M. R., Leet, J. E., Dufresne, C., Doubek, D. L., Schmidt, J. M., Cerny, R. L., Hooper, J. N. A., & Rutzler, K. C. (1991) · Journal of Medicinal Chemistry · doi:10.1021/jm00115a027 · Cited by 191 · see citing works

Cytotoxic Bisindole Alkaloids from a Marine Sponge Spongosorites sp.

Bao, B., Sun, Q., Yao, X., et al. (2005) · Journal of Natural Products · doi:10.1021/np049577a · Cited by 187 · see citing works

Producing drugs from marine sponges

Belarbi, E. (2003) · Biotechnology Advances · doi:10.1016/s0734-9750(03)00100-9 · Cited by 185 · see citing works

Isolation and structure elucidation of onnamide A, a new bioactive metabolite of a marine sponge, Theonella sp

Sakemi, S., Ichiba, T., Kohmoto, S., et al. (1988) · Journal of the American Chemical Society · doi:10.1021/ja00222a068 · Cited by 183 · see citing works

Motuporin, A Potent Protein Phosphatase Inhibitor Isolated from the Papua New Guinea Sponge Theonella swinhoei Gray

de Silva, E. D., Williams, D. E. J., Andersen, R. J., et al. (1992) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)91674-5 · Cited by 179 · see citing works

Three New Manzamine Alkaloids from a Common Indonesian Sponge and Their Activity against Infectious and Tropical Parasitic Diseases

Rao, K. V., Kasanah, N., Wahyuono, S., Tekwani, B. L., Schinazi, R. F., & Hamann, M. T. (2004) · Journal of Natural Products · doi:10.1021/np0400095 · Cited by 158 · see citing works

Cytotoxic peptides from the marine sponge Cymbastela sp.

Coleman, J. E., de Silva, E. D., Kong, F., et al. (1995) · Tetrahedron · doi:10.1016/0040-4020(95)00646-p · Cited by 157 · see citing works

Zampanolide, a new cytotoxic marcrolide from a marine sponge

Tanaka, J., & Higa, T. (1996) · Tetrahedron Letters · doi:10.1016/0040-4039(96)01149-5 · Cited by 154 · see citing works

Aldisine Alkaloids from the Philippine Sponge Stylissa massa Are Potent Inhibitors of Mitogen-Activated Protein Kinase Kinase-1 (MEK-1)

Taşdemir, D., Mallon, R. G., Greenstein, M., et al. (2001) · Journal of Medicinal Chemistry · doi:10.1021/jm0102856 · Cited by 153 · see citing works

Antiviral and antitumor agents from a New Zealand sponge, Mycale sp. 2. Structures and solution conformations of mycalamides A and B

Perry, N. B., Blunt, J. W., Munro, M. H. G., et al. (1990) · The Journal of Organic Chemistry · doi:10.1021/jo00288a037 · Cited by 152 · see citing works

Bioactive marine metabolites. 48. Cinachyrolide A: a potent cytotoxic macrolide possessing two spiro ketals from marine sponge Cinachyra sp

Fusetani, N., Shinoda, K., & Matsunaga, S. (1993) · Journal of the American Chemical Society · doi:10.1021/ja00063a017 · Cited by 152 · see citing works

Sintokamides A to E, Chlorinated Peptides from the Sponge Dysidea sp. that Inhibit Transactivation of the N-Terminus of the Androgen Receptor in Prostate Cancer Cells

Sadar, M. D., Williams, D. E., Mawji, N. R., Patrick, B. O., Wikanta, T., Chasanah, E., Irianto, H. E., van Soest, R. W. M., & Andersen, R. J. (2008) · Organic Letters · doi:10.1021/ol802021w · Cited by 152 · see citing works

Altohyrtin A, a potent anti-tumor macrolide from the Okinawan marine sponge Hyrtios altum

Kobayashi, M., Aoki, S., Sakai, H., et al. (1993) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)73564-7 · Cited by 146 · see citing works

Manzamine B and E and Ircinal A Related Alkaloids from an Indonesian Acanthostrongylophora Sponge and Their Activity against Infectious, Tropical Parasitic, and Alzheimer's Diseases

Rao, K. V., Donia, M. S., Peng, J., García‐Palomero, E., Alonso, D. A., Martı́nez, A., Medina, M., Franzblau, S. G., Tekwani, B. L., Khan, S. I., et al. (2006) · Journal of Natural Products · doi:10.1021/np0601399 · Cited by 142 · see citing works

Leucascandrolide A, a New Type of Macrolide: The first powerfully bioactive metabolite of calcareous sponges (Leucascandra caveolata, a new genus from the coral sea)

D’Ambrosio, M., Guerriero, A., Pietra, F., et al. (1996) · Helvetica Chimica Acta · doi:10.1002/hlca.19960790107 · Cited by 135 · see citing works

Terpenoids with antifouling activity against barnacle larvae from the marine sponge Acanthella cavernosa

Hirota, H., Tomono, Y., & Fusetani, N. (1996) · Tetrahedron · doi:10.1016/0040-4020(95)01079-3 · Cited by 133 · see citing works

Tedanolide: a potent cytotoxic macrolide from the Caribbean sponge Tedania ignis

Schmitz, F. J., Gunasekera, S. P., Gopichand, Y., et al. (1984) · Journal of the American Chemical Society · doi:10.1021/ja00335a069 · Cited by 132 · see citing works

Bioactive marine metabolites. Part 35. Cytotoxic metabolites of the marine sponge Mycale adhaerens Lambe

Fusetani, N., Sugawara, T., Matsunaga, S., et al. (1991) · The Journal of Organic Chemistry · doi:10.1021/jo00016a031 · Cited by 131 · see citing works

Mycalolides A – C, hybrid macrolides of ulapualides and halichondramide, from a sponge of the genus

Fusetani, N., Yasumuro, K., Matsunaga, S., et al. (1989) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)99131-7 · Cited by 131 · see citing works

Absolute stereostructure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge Theonella swinhoei

Kitagawa, I., Kobayashi, M., Katori, T., et al. (1990) · Journal of the American Chemical Society · doi:10.1021/ja00165a094 · Cited by 127 · see citing works

New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections, and inflammatory diseases

Yousaf, M., Hammond, N. L., Peng, J., Wahyuono, S., McIntosh, K. A., Charman, W. N., Mayer, A. M. S., & Hamann, M. T. (2004) · Journal of Medicinal Chemistry · doi:10.1021/jm030475b · Cited by 119 · see citing works

Orbiculamide A: a novel cytotoxic cyclic peptide from a marine sponge Theonella sp

Fusetani, N., Sugawara, T., Matsunaga, S., et al. (1991) · Journal of the American Chemical Society · doi:10.1021/ja00020a080 · Cited by 116 · see citing works

Isolation and First Total Synthesis of PM050489 and PM060184, Two New Marine Anticancer Compounds

Martín, M. J., Coello, L., Fernández, R., Reyes, F., Rodríguez, A., Murcia, C., Garranzo, M., Mateo, C., Sánchez-Sancho, F., Bueno, S., et al. (2013) · Journal of the American Chemical Society · doi:10.1021/ja404578u · Cited by 114 · see citing works

Dysinosin A: A Novel Inhibitor of Factor VIIa and Thrombin from a New Genus and Species of Australian Sponge of the Family Dysideidae

Carroll, A. R., Pierens, G. K., Fechner, G. A., et al. (2002) · Journal of the American Chemical Society · doi:10.1021/ja020814a · Cited by 114 · see citing works

Homophymine A, an Anti-HIV Cyclodepsipeptide from the Sponge Homophymia sp.

Zampella, A., Sepe, V., Luciano, P., et al. (2008) · The Journal of Organic Chemistry · doi:10.1021/jo800583b · Cited by 114 · see citing works

Bioactive marine metabolites. 41. Theopederins A-E, potent antitumor metabolites from a marine sponge, Theonella sp

Fusetani, N., Sugawara, T., & Matsunaga, S. (1992) · The Journal of Organic Chemistry · doi:10.1021/jo00040a021 · Cited by 113 · see citing works

Batzelladine alkaloids from the caribbean sponge Monanchora unguifera and the significant activities against HIV-1 and AIDS opportunistic infectious pathogens

Hua, H., Peng, J., Dunbar, D. C., Schinazi, R. F., Andrews, A. G. D. C., Cuevas, C., García‐Fernández, L., Kelly, M., & Hamann, M. T. (2007) · Tetrahedron · doi:10.1016/j.tet.2007.08.005 · Cited by 113 · see citing works

: Isolation and structure of halistatin 1 from the eastern Indian Ocean marine sponge Phakellia carteri

Pettit, G. R., Tan, R., Gao, F., et al. (1993) · The Journal of Organic Chemistry · doi:10.1021/jo00061a030 · Cited by 112 · see citing works

Dragmacidin F: A New Antiviral Bromoindole Alkaloid from the Mediterranean Sponge Halicortex sp.

Cutignano, A., Bifulco, G., Bruno, I., et al. (2000) · Tetrahedron · doi:10.1016/s0040-4020(00)00281-7 · Cited by 108 · see citing works

Manadomanzamines A and B: A Novel Alkaloid Ring System with Potent Activity against Mycobacteria and HIV-1

Peng, J., Hu, J., Kazi, A. B., Li, Z., Avery, M. A., Peraud, O., Hill, R. T., Franzblau, S. G., Zhang, F., Schinazi, R. F., et al. (2003) · Journal of the American Chemical Society · doi:10.1021/ja030087z · Cited by 106 · see citing works

Antimicrobial Activity and Cytotoxicity of Bis(indole) Alkaloids from the Sponge Spongosorites sp.

Oh, K., Mar, W., Kim, S., Kim, J.-Y., Lee, T., Kim, J.-G., Shin, D., Sim, C. J., & Shin, J. (2006) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.29.570 · Cited by 106 · see citing works

Dactylolide, a New Cytotoxic Macrolide from the Vanuatu SpongeDactylospongia sp.

Cutignano, A., Bruno, I., Bifulco, G., Casapullo, A., Debitus, C., Gomez‐Paloma, L., & Riccio, R. (2001) · European Journal of Organic Chemistry · doi:10.1002/1099-0690(200102)2001:4 · Cited by 106 · see citing works

Miraziridine A, a Novel Cysteine Protease Inhibitor from the Marine Sponge Theonella aff. mirabilis1

Nakao, Y., Fujita, M., Warabi, K., et al. (2000) · Journal of the American Chemical Society · doi:10.1021/ja001859j · Cited by 105 · see citing works

Bioactive marine metabolites. 24. Isolation and structure elucidation of calyculins B, C, and D, novel antitumor metabolites, from the marine sponge Discodermia calyx

Kato, Y., Fusetani, N., Matsunaga, S., et al. (1988) · The Journal of Organic Chemistry · doi:10.1021/jo00252a009 · Cited by 104 · see citing works

8-Hydroxymanzamine A, a β-Carboline Alkaloid from a Sponge, Pachypellina sp.

Ichiba, T., Corgiat, J. M., Scheuer, P. J., & Kelly‐Borges, M. (1994) · Journal of Natural Products · doi:10.1021/np50103a027 · Cited by 104 · see citing works

Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the okinawan marine sponge Hyrtios altum.

KOBAYASHI, M., Aoki, S., SAKAI, H., et al. (1993) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.41.989 · Cited by 104 · see citing works

Cytotoxic Pyrroloiminoquinones from Four New Species of South African Latrunculid Sponges

Antunes, E. M., Beukes, D. R., Kelly, M., et al. (2004) · Journal of Natural Products · doi:10.1021/np034084b · Cited by 102 · see citing works

Macrocyclic antifungal metabolites from the Spanish dancer nudibranch Hexabranchus sanguineus and sponges of the genus Halichondria

Kernan, M. R., Molinski, T. F., & Faulkner, D. J. (1988) · The Journal of Organic Chemistry · doi:10.1021/jo00256a021 · Cited by 102 · see citing works

Mauritiamine, a New Antifouling Oroidin Dimer from the Marine Sponge Agelas mauritiana

Tsukamoto, S., Kato, H., Hirota, H., et al. (1996) · Journal of Natural Products · doi:10.1021/np960113p · Cited by 102 · see citing works

Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine Cyanobacterium Phormidium sp.

Williamson, R. T., Boulanger, A., Vulpanovici, A., et al. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo020240s · Cited by 102 · see citing works

Cortistatins J, K, L, novel abeo-9(10-19)-androstane-type steroidal alkaloids with isoquinoline unit, from marine sponge Corticium simplex

Aoki, S., Watanabe, Y., TANABE, D., et al. (2007) · Tetrahedron Letters · doi:10.1016/j.tetlet.2007.05.003 · Cited by 101 · see citing works

Cytotoxic Sterol Derivatives from a Marine Sponge Homaxinella sp.

Mansoor, T. A., Hong, J., Lee, C., et al. (2005) · Journal of Natural Products · doi:10.1021/np0496690 · Cited by 100 · see citing works

Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge

Hamada, T., Matsunaga, S., Fujiwara, M., et al. (2010) · Journal of the American Chemical Society · doi:10.1021/ja104616z · Cited by 99 · see citing works

Bioactive Guanidine Alkaloids from Two Caribbean Marine Sponges

Laville, R., Thomas, O. P., Berrué, F., et al. (2009) · Journal of Natural Products · doi:10.1021/np900244g · Cited by 98 · see citing works

Lasonolide A, A New Cytotoxic Macrolide from the Marine Sponge Forcepia sp.

Horton, P. A., Koehn, F. E., Longley, R. E., et al. (1994) · Journal of the American Chemical Society · doi:10.1021/ja00092a081 · Cited by 98 · see citing works

Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis

Kashman, Y., Koren‐Goldshlager, G., Gravalos, M. D. G., et al. (1999) · Tetrahedron Letters · doi:10.1016/s0040-4039(98)02467-8 · Cited by 96 · see citing works

Monanchocidin: A New Apoptosis-Inducing Polycyclic Guanidine Alkaloid from the Marine Sponge Monanchora pulchra

Guzii, A. G., Makarieva, T. N., Денисенко, В. А., Dmitrenok, P. S., Kuzmich, A. S., Dyshlovoy, S. A., Krasokhin, V. B., & Stonik, V. A. (2010) · Organic Letters · doi:10.1021/ol101716x · Cited by 96 · see citing works

Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp.

Paterson, I., Dalby, S. M., Roberts, J. C., Naylor, G. J., Guzmán, E. A., Isbrucker, R. A., Pitts, T. P., Linley, P., Divlianska, D. B., Reed, J. K., et al. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201007719 · Cited by 96 · see citing works

The Kapakahines, Cyclic Peptides from the Marine Sponge Cribrochalina olemda

Yeung, B. K. S., Nakao, Y., Kinnel, R. B., et al. (1996) · The Journal of Organic Chemistry · doi:10.1021/jo960725e · Cited by 93 · see citing works

Antibiotic and Cytotoxic Activity of Brominated Compounds from the Marine Sponge Verongia aerophoba

Teeyapant, R., Woerdenbag, H. J., Kreis, P., et al. (1993) · Zeitschrift für Naturforschung C · doi:10.1515/znc-1993-11-1218 · Cited by 91 · see citing works

Marine pyridoacridine alkaloids and synthetic analogues as antitumor agents

Delfourne, E., & Bastide, J. (2002) · Medicinal Research Reviews · doi:10.1002/med.10032 · Cited by 91 · see citing works

Dysidavarones A–D, New Sesquiterpene Quinones from the Marine Sponge Dysidea avara

Jiao, W., Huang, X., yang, J., et al. (2011) · Organic Letters · doi:10.1021/ol202994c · Cited by 88 · see citing works

Renieramycin J, a Highly Cytotoxic Tetrahydroisoquinoline Alkaloid, from a Marine Sponge Neopetrosia sp.

Oku, N., Matsunaga, S., van Soest, R. W. M., et al. (2003) · Journal of Natural Products · doi:10.1021/np030092g · Cited by 88 · see citing works

Antimalarial Activity of Pyrroloiminoquinones from the Australian Marine SpongeZyzzyasp.

Davis, R. A., Buchanan, M. S., Duffy, S., et al. (2012) · Journal of Medicinal Chemistry · doi:10.1021/jm3002795 · Cited by 88 · see citing works

Microsclerodermins F–I, Antitumor and Antifungal Cyclic Peptides from the Lithistid Sponge Microscleroderma sp.

Qureshi, A., Colin, P. L., & Faulkner, D. J. (2000) · Tetrahedron · doi:10.1016/s0040-4020(00)00286-6 · Cited by 86 · see citing works

Antibacterial activity against resistant bacteria and cytotoxicity of four alkaloid toxins isolated from the marine sponge Arenosclera brasiliensis

Torres, Y. R., Berlinck, R. G. S., Nascimento, G. G. F., et al. (2002) · Toxicon · doi:10.1016/s0041-0101(01)00286-0 · Cited by 86 · see citing works

Total Synthesis of Ageladine A, an Angiogenesis Inhibitor from the Marine Sponge Agelas nakamurai

Meketa, M. L., & Weinreb, S. M. (2006) · Organic Letters · doi:10.1021/ol0602304 · Cited by 85 · see citing works

Calyculins E, F, G, and H, additional inhibitors of protein phosphatases 1 and 2a, from the marine sponge discodermia calyx

Matsunaga, S., Fujiki, H., Sakata, D., et al. (1991) · Tetrahedron · doi:10.1016/s0040-4020(01)96031-4 · Cited by 85 · see citing works

Marine natural products. XXIII. Three new cytotoxic dimeric macrolides, swinholides B and C and isoswinholide A, congeners of swinholide A, from the Okinawan marine sponge Theonella swinhoei.

Kobayashi, M., Tanaka, J., Katori, T., et al. (1990) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.38.2960 · Cited by 85 · see citing works

Naamidine A Is an Antagonist of the Epidermal Growth Factor Receptor and an in Vivo Active Antitumor Agent

Copp, B. R., Fairchild, C. R., Cornell, L., et al. (1998) · Journal of Medicinal Chemistry · doi:10.1021/jm980294n · Cited by 85 · see citing works

Anti-parasitic Guanidine and Pyrimidine Alkaloids from the Marine Sponge Monanchora arbuscula

Santos, M. F. C., Harper, P. M., Williams, D. E. J., et al. (2015) · Journal of Natural Products · doi:10.1021/acs.jnatprod.5b00070 · Cited by 84 · see citing works

Structure of swinholide A, a potent cytotoxic macrolide from the Okinawan marine sponge

Kobayashi, M., Tanaka, J., Katori, T., et al. (1989) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)99170-6 · Cited by 84 · see citing works

Thiaplakortones A–D: Antimalarial Thiazine Alkaloids from the Australian Marine Sponge Plakortis lita

Davis, R. A., Duffy, S., Fletcher, S., Avery, V. M., & Quinn, R. J. (2013) · The Journal of Organic Chemistry · doi:10.1021/jo400988y · Cited by 83 · see citing works

Halenaquinone and xestoquinone derivatives, inhibitors of Cdc25B phosphatase from a Xestospongia sp.

Cao, S., Foster, C. A., Brisson, M., et al. (2004) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2004.11.039 · Cited by 83 · see citing works

Isolation and structures of haterumalides NA, NB, NC, ND, and NE, novel macrolides from an Okinawan Sponge Ircinia sp.

Takada, N., Sato, H., Suenaga, K., et al. (1999) · Tetrahedron Letters · doi:10.1016/s0040-4039(99)01291-5 · Cited by 82 · see citing works

Xesto- and halenaquinone derivatives from a sponge, Adocia sp., from Truk lagoon

Schmitz, F. J., & Bloor, S. J. (1988) · The Journal of Organic Chemistry · doi:10.1021/jo00252a007 · Cited by 82 · see citing works

Hyrtioreticulins A–E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus

Yamanokuchi, R., Imada, K., Miyazaki, M., Kato, H., Watanabe, T., Fujimuro, M., Saeki, Y., Yoshinaga, S., Terasawa, H., Iwasaki, N., et al. (2012) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2012.05.044 · Cited by 81 · see citing works

Aciculitins A−C: Cytotoxic and Antifungal Cyclic Peptides from the Lithistid Sponge Aciculites orientalis

Bewley, C. A., He, H., Williams, D. H., et al. (1996) · Journal of the American Chemical Society · doi:10.1021/ja953628w · Cited by 80 · see citing works

Variolin B and its derivate deoxy-variolin B: New marine natural compounds with cyclin-dependent kinase inhibitor activity

Simone, M., Erba, E., Damia, G. L. M., et al. (2005) · European Journal of Cancer · doi:10.1016/j.ejca.2005.05.015 · Cited by 80 · see citing works

Isohomohalichondrin B, a new antitumour polyether macrolide from the New Zealand deep-water sponge Lissodendoryx sp.

Litaudon, M., Hart, J. B., Blunt, J. W., et al. (1994) · Tetrahedron Letters · doi:10.1016/s0040-4039(00)78563-7 · Cited by 80 · see citing works

Eight new cytotoxic metabolites closely related to onnamide A from two marine sponges of the genus Theonella

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