Quorum Sensing in Life Support Systems: The MELiSSA Loop

Quorum sensing signal-response systems in Gram-negative bacteria

Papenfort, K., & Bassler, B. L. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.89 · Cited by 2,256 · see citing works

Bacterial Quorum-Sensing Network Architectures

Ng, W., & Bassler, B. L. (2009) · Annual Review of Genetics · doi:10.1146/annurev-genet-102108-134304 · Cited by 1,686 · see citing works

<i>Ruminococcus bromii</i> is a keystone species for the degradation of resistant starch in the human colon

Ze, X., Duncan, S. H., Louis, P., & Flint, H. J. (2012) · The ISME Journal · doi:10.1038/ismej.2012.4 · Cited by 1,060 · see citing works

The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule

Schauder, S., Shokat, K. M., Surette, M. G., & Bassler, B. L. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02532.x · Cited by 1,039 · see citing works

Quorum sensing inhibitors: An overview

Kalia, V. C. (2012) · Biotechnology Advances · doi:10.1016/j.biotechadv.2012.10.004 · Cited by 989 · see citing works

Bacterially Speaking

Bassler, B. L., & Losick, R. M. (2006) · Cell · doi:10.1016/j.cell.2006.04.001 · Cited by 983 · see citing works

N -Acylhomoserine Lactones Undergo Lactonolysis in a pH-, Temperature-, and Acyl Chain Length-Dependent Manner during Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa

Yates, E. A., Philipp, B., Buckley, C. M. F., Atkinson, S., Chhabra, S. R., Sockett, R. E., Goldner, M., Dessaux, Y., Cámara, M., Smith, H. C., et al. (2002) · Infection and Immunity · doi:10.1128/iai.70.10.5635-5646.2002 · Cited by 621 · see citing works

A new class of homoserine lactone quorum-sensing signals

Schaefer, A. L., Greenberg, E. P., Oliver, C. M., Oda, Y., Huang, J., Bittan-Banin, G., Peres, C. M., Schmidt, S., Juhaszova, K., Sufrin, J. R., et al. (2008) · Nature · doi:10.1038/nature07088 · Cited by 412 · see citing works

Members of the human gut microbiota involved in recovery from Vibrio cholerae infection

Hsiao, A., Ahmed, A. M. S., Subramanian, S., Griffin, N. W., Drewry, L. L., Petri, W. A., Haque, R., Ahmed, T., & Gordon, J. I. (2014) · Nature · doi:10.1038/nature13738 · Cited by 387 · see citing works

Phylotypes related to Ruminococcus bromii are abundant in the large bowel of humans and increase in response to a diet high in resistant starch

Abell, G. C. J., Cooke, C. M., Bennett, C. N., Conlon, M. A., & McOrist, A. L. (2008) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2008.00527.x · Cited by 233 · see citing works

The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase The GenBank accession number for the sequence determined in this work is AF286536.

Laue, B. E., Jiang, Y., Chhabra, S. R., Jacob, S., Stewart, G. S. A. B., Hardman, A., Downie, J. A., O’Gara, F., & Williams, P. M. (2000) · Microbiology · doi:10.1099/00221287-146-10-2469 · Cited by 211 · see citing works

Spaceflight Promotes Biofilm Formation by Pseudomonas aeruginosa

Kim, W., Tengra, F. K., Young, Z. D., Shong, J., Marchand, N., Chan, H. K., Pangule, R. C., Parra, M. P., Dordick, J. S., Plawsky, J. L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0062437 · Cited by 211 · see citing works

‘MELISSA: a loop of interconnected bioreactors to develop life support in Space’.

Gòdia, F., Albiol, J., Montesinos, J. L., Pérez, J., Creus, N., Cabello, F., Mengual, X., Montras, A., & Lasseur, C. (2002) · Journal of Biotechnology · doi:10.1016/s0168-1656(02)00222-5 · Cited by 187 · see citing works

Microbial ecology of the closed artificial ecosystem MELiSSA (Micro-Ecological Life Support System Alternative): Reinventing and compartmentalizing the Earth’s food and oxygen regeneration system for long-haul space exploration missions

Hendrickx, L., De Wever, H., Hermans, V., Mastroleo, F., Morin, N., Wilmotte, A., Janssen, P., & Mergeay, M. (2006) · Research in Microbiology · doi:10.1016/j.resmic.2005.06.014 · Cited by 181 · see citing works

Quorum sensing in Cyanobacteria: N -octanoyl-homoserine lactone release and response, by the epilithic colonial cyanobacterium Gloeothece PCC6909

Sharif, D. I., Gallon, J., Smith, C. J., & Dudley, E. (2008) · The ISME Journal · doi:10.1038/ismej.2008.68 · Cited by 174 · see citing works

Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling

Shiner, E. K., Terentyev, D. A., Bryan, A., Sennoune, S. R., Martı́nez–Zaguilán, R., Li, G., Györke, S., Williams, S. C., & Rumbaugh, K. P. (2006) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00734.x · Cited by 159 · see citing works

Spaceflight and modeled microgravity effects on microbial growth and virulence

Rosenzweig, J. A., Abogunde, O., Thomas, K., Lawal, A., Nguyen, Y.-U., Sodipe, A., & Jejelowo, O. A. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2237-8 · Cited by 156 · see citing works

Quorum sensing positively regulates flagellar motility in pathogenic V ibrio harveyi

Yang, Q., & Defoirdt, T. (2014) · Environmental Microbiology · doi:10.1111/1462-2920.12420 · Cited by 150 · see citing works

Quorum quenching activity in Anabaena sp. PCC 7120: identification of AiiC, a novel AHL-acylase

Romero, M., Diggle, S. P., Heeb, S., Cámara, M., & Otero, A. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2007.01046.x · Cited by 147 · see citing works

Identification of Acyl-Homoserine Lactone Signal Molecules Produced by Nitrosomonas europaea Strain Schmidt

Burton, E. O., Read, H. W., Pellitteri-Hahn, M. C., & Hickey, W. J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.8.4906-4909.2005 · Cited by 123 · see citing works

MELiSSA: THE EUROPEAN PROJECT OF CLOSED LIFE SUPPORT SYSTEM

Lasseur, C., Brunet, J., de Weever, H., Dixon, M., Dussap, C., Gòdia, F., Leys, N., Mergeay, M., & Straeten, D. V. D. (2006) · Institutional Repositories DataBase (IRDB) · Cited by 111 · see citing works

Experimental design and environmental parameters affect <i>Rhodospirillum rubrum</i> S1H response to space flight

Mastroleo, F., Van Houdt, R., Leroy, B., Benotmane, M. A., Janssen, A., Mergeay, M., Vanhavere, F., Hendrickx, L., Wattiez, R., & Leys, N. (2009) · The ISME Journal · doi:10.1038/ismej.2009.74 · Cited by 68 · see citing works

Quorum Quenching of Nitrobacter winogradskyi Suggests that Quorum Sensing Regulates Fluxes of Nitrogen Oxide(s) during Nitrification

Mellbye, B. L., Giguere, A. T., Bottomley, P. J., & Sayavedra‐Soto, L. A. (2016) · mBio · doi:10.1128/mbio.01753-16 · Cited by 67 · see citing works

The MELISSA pilot plant facility as an integration test-bed for advanced life support systems

Gòdia, F., Albiol, J., Pérez, J., Creus, N., Cabello, F., Montràs, A., Masot, A., & Lasseur, C. (2004) · Advances in Space Research · doi:10.1016/j.asr.2003.08.038 · Cited by 58 · see citing works

Simulation of the MELiSSA closed loop system as a tool to define its integration strategy

Poughon, L., Farges, B., Dussap, C., Gòdia, F., & Lasseur, C. (2009) · Advances in Space Research · doi:10.1016/j.asr.2009.07.021 · Cited by 54 · see citing works

Possible quorum sensing in the rumen microbial community: detection of quorum-sensing signal molecules from rumen bacteria

Mitsumori, M., Xu, L., Kajikawa, H., KURIHARA, M., Tajima, K., Hai, J., & Takénaka, A. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(02)01192-8 · Cited by 49 · see citing works

Nitrite-Oxidizing Bacterium Nitrobacter winogradskyi Produces N -Acyl-Homoserine Lactone Autoinducers

Mellbye, B. L., Bottomley, P. J., & Sayavedra‐Soto, L. A. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.01103-15 · Cited by 48 · see citing works

Proteome analysis at the subcellular level of the cyanobacterium<i>Spirulina platensis</i>in response to low-temperature stress conditions

Hongsthong, A., Sirijuntarut, M., Prommeenate, P., Lertladaluck, K., Porkaew, K., Cheevadhanarak, S., & Tanticharoen, M. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2008.01330.x · Cited by 47 · see citing works

New insight into the photoheterotrophic growth of the isocytrate lyase-lacking purple bacterium Rhodospirillum rubrum on acetate

Leroy, B., Meur, Q. D., Moulin, C., Wégria, G., & Wattiez, R. (2015) · Microbiology · doi:10.1099/mic.0.000067 · Cited by 44 · see citing works

Detection of possible AI-2-mediated quorum sensing system in commensal intestinal bacteria

Lukáš, F., GORENC, G., & Kopečný, J. (2008) · Folia Microbiologica · doi:10.1007/s12223-008-0030-1 · Cited by 44 · see citing works

Quorum sensing N-acylhomoserine lactone signals affect nitrogen fixation in the cyanobacterium Anabaena sp. PCC7120

Romero, M., Muro-Pastor, A. M., & Otero, A. (2010) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2010.02175.x · Cited by 40 · see citing works

Dynamic Aspects and Controllability of the MELiSSA Project: A Bioregenerative System to Provide Life Support in Space

Farges, B., Poughon, L., Creuly, C., Cornet, J., Dussap, C., & Lasseur, C. (2008) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-008-8292-2 · Cited by 35 · see citing works

Modelled microgravity cultivation modulates N-acylhomoserine lactone production in Rhodospirillum rubrum S1H independently of cell density

Mastroleo, F., Houdt, R. V., Atkinson, S., Mergeay, M., Hendrickx, L., Wattiez, R., & Leys, N. (2013) · Microbiology · doi:10.1099/mic.0.066415-0 · Cited by 35 · see citing works

A New Acyl-homoserine Lactone Molecule Generated by Nitrobacter winogradskyi

Shen, Q., Gao, J., Liu, J., Liu, S., Liu, Z., Wang, Y., Guo, B., Zhuang, X., & Zhuang, G. (2016) · Scientific Reports · doi:10.1038/srep22903 · Cited by 32 · see citing works

Possible applications of aquatic bioregenerative life support modules for food production in a Martian base

Bluem, V., & París, F. (2003) · Advances in Space Research · doi:10.1016/s0273-1177(02)00659-2 · Cited by 31 · see citing works

CEEF: CLOSED ECOLOGY EXPERIMENT FACILITIES

Tako, Y., Arai, R., Tsuga, S., Komatsubara, O., Masuda, T., Nozoe, S., & Nitta, K. (2010) · Gravitational and Space Research · Cited by 29 · see citing works

Environmental biotechnology

Borglin, S. E., & van der Meer, J. P. (2010) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2010.04.002 · Cited by 27 · see citing works

REGULATION OF L-ISOLEUCINE BIOSYNTHESIS IN THE PHOTOSYNTHETIC BACTERIUM RHODOSPIRILLUM RUBRUM

Ning, C., & Gest, H. (1966) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.56.6.1823 · Cited by 22 · see citing works

Quorum sensing influences growth and photosynthetic membrane production in high-cell-density cultivations of Rhodospirillum rubrum

Carius, L., Carius, A. B., McIntosh, M., & Grammel, H. (2013) · BMC Microbiology · doi:10.1186/1471-2180-13-189 · Cited by 17 · see citing works

Test of an anaerobic prototype reactor coupled with a filtration unit for production of VFAs

Poughon, L., Creuly, C., Farges, B., Dussap, C., Schiettecatte, W., Jovetic, S., & Wever, H. D. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.12.052 · Cited by 11 · see citing works

BIOS-4 as an embodiment of CELSS development conception

Bartsev, S. I., Mezhevikin, V. V., & Okhonin, V. A. (1996) · Advances in Space Research · doi:10.1016/0273-1177(95)00809-s · Cited by 10 · see citing works

Construction and phenotypic characterization of M68, an RruI quorum sensing knockout mutant of the photosynthetic alphaproteobacterium Rhodospirillum rubrum

Condori-Catachura, S., Atkinson, S., Leys, N., Wattiez, R., & Mastroleo, F. (2016) · Research in Microbiology · doi:10.1016/j.resmic.2016.02.006 · Cited by 4 · see citing works

The flate and effects of micropollutants in a biological life support system

Pycke, B. F. G. (2009) · Ghent University Academic Bibliography (Ghent University) · Cited by 4 · see citing works

Mission simulation as an approach to develop requirements for automation in advanced life support systems

Erickson, J. D., Eckelkamp, R. E., Barta, D. J., & Dragg, J. L. (1996) · Advances in Space Research · doi:10.1016/0273-1177(95)00808-r · Cited by 2 · see citing works

Biologically-Based and Physiochemical Life Support and In Situ Resource Utilization for Exploration of the Solar System—Reviewing the Current State and Defining Future Development Needs

Keller, R. J., Porter, W., Goli, K., Rosenthal, R., Butler, N., & Jones, J. A. (2021) · Life · doi:10.3390/life11080844 · Cited by 23 · see citing works

Biofilm dynamics in space and their potential for sustainable space exploration – A comprehensive review

Sowmeya, V. G., & Sathiavelu, M. (2024) · Life Sciences in Space Research · doi:10.1016/j.lssr.2024.08.006 · Cited by 3 · see citing works

Primer-Like Inhibitors for DNA Repair Enzymes of the AML-HL60 and WERI-1A/Y79 Malignant Cells

Stovbun, S. V., Ermakov, K. V., Bukhvostov, A. A., Vedenkin, A. S., & Kuznetsov, D. A. (2019) · Advances in Enzyme Research · doi:10.4236/aer.2019.73003 · Cited by 3 · see citing works

MELISSA: Current Status and Future Development Program

Lasseur, C., Tamponnet, C., & Savage, C. J. (1993) · SAE technical papers on CD-ROM/SAE technical paper series · doi:10.4271/932126 · Cited by 2 · see citing works

MELiSSA the minimal biosphere: Human life, waste and refuge in deep space

Walker, J. J., & Granjou, C. (2017) · Futures · doi:10.1016/j.futures.2016.12.001 · Cited by 58 · see citing works

Reactivation of Microbial Strains and Synthetic Communities After a Spaceflight to the International Space Station: Corroborating the Feasibility of Essential Conversions in the MELiSSA Loop

Ilgrande, C., Mastroleo, F., Christiaens, M. E. R., Lindeboom, R. E. F., Prat, D., Hoey, O. V., Ambrožová, I., Coninx, I., Heylen, W., Pommerening‐Röser, A., et al. (2019) · Astrobiology · doi:10.1089/ast.2018.1973 · Cited by 15 · see citing works

Microbial ecology of the closed artificial ecosystem MELiSSA (Micro-Ecological Life Support System Alternative): Reinventing and compartmentalizing the Earth’s food and oxygen regeneration system for long-haul space exploration missions

Hendrickx, L., De Wever, H., Hermans, V., Mastroleo, F., Morin, N., Wilmotte, A., Janssen, P., & Mergeay, M. (2006) · Research in Microbiology · doi:10.1016/j.resmic.2005.06.014 · Cited by 181 · see citing works

Gravitational and Space Biology 23(2) August 2010 3 MELiSSA: THE EUROPEAN PROJECT OF CLOSED LIFE SUPPORT SYSTEM

Lasseur, C., Brunet, J., de Weever, H., Dixon, M., Dussap, C., Gòdia, F., Leys, N., Mergeay, M., Van, D., & Straeten, D. (2014)