RNA as a target and an initiator of post-transcriptional gene silencing in trangenic plants

Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression.

van der Krol, A. R., Mur, L. A., Beld, M., Mol, J. N., & Stuitje, A. R. (1990) · The Plant Cell · doi:10.1105/tpc.2.4.291 · Cited by 1,204

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

Napoli, C., Lemieux, C., & Jorgensen, R. (1990) · The Plant Cell · doi:10.2307/3869076 · Cited by 1,101

RNA-directed de novo methylation of genomic sequences in plants

Wassenegger, M., Heimes, S., Riedel, L., & Sänger, H. L. (1994) · Cell · doi:10.1016/0092-8674(94)90119-8 · Cited by 929

Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA.

Kumagai, M. H., Donson, J., della-Cioppa, G., Harvey, D., Hanley, K., & Grill, L. K. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.5.1679 · Cited by 716

How and Why Do Plants Inactivate Homologous (Trans)genes?

Matzke, M. A., & Matzke, A. (1995) · Plant Physiology · doi:10.1104/pp.107.3.679 · Cited by 512

ANTISENSE RNA CONTROL IN BACTERIA, PHAGES, AND PLASMIDS

Wagner, E. G. H., & Simons, R. W. (1994) · Annual Review of Microbiology · doi:10.1146/annurev.mi.48.100194.003433 · Cited by 438

Transgene copy number can be positively or negatively associated with transgene expression

Hobbs, S. L. A., Warkentin, T. D., & DeLong, C. M. O. (1993) · Plant Molecular Biology · doi:10.1007/bf00039614 · Cited by 394

Identification and genetic analysis of normal and mutant phytoene synthase genes of tomato by sequencing, complementation and co-suppression

Fray, R. G., & Grierson, D. (1993) · Plant Molecular Biology · doi:10.1007/bf00047400 · Cited by 392

Suppression of Virus Accumulation in Transgenic Plants Exhibiting Silencing of Nuclear Genes.

English, J. J., Mueller, E., & Baulcombe, D. C. (1996) · The Plant Cell · doi:10.1105/tpc.8.2.179 · Cited by 371

Untranslatable transcripts of the tobacco etch virus coat protein gene sequence can interfere with tobacco etch virus replication in transgenic plants and protoplasts

Lindbo, J. A., & Dougherty, W. G. (1992) · Virology · doi:10.1016/0042-6822(92)90595-g · Cited by 311

Suppression of beta-1,3-glucanase transgene expression in homozygous plants.

de Carvalho, F., Gheysen, G., Kushnir, S., Van Montagu, M., Inzé, D., & Castresana, C. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05324.x · Cited by 304

Expression of single copies of a strongly expressed 35S transgene can be silenced post‐transcriptionally

Elmayan, T., & Vaucheret, H. (1996) · The Plant Journal · doi:10.1046/j.1365-313x.1996.9060787.x · Cited by 294

Transgene‐mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover

Van Blokland, R., Van der Geest, N., Mol, J. N. M., & Kooter, J. M. (1994) · The Plant Journal · doi:10.1046/j.1365-313x.1994.6060861.x · Cited by 294

Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity

Park, Y., Papp, I., Moscone, E. A., Iglesias, V., Vaucheret, H., Matzke, A. J. M., & Matzke, M. A. (1996) · The Plant Journal · doi:10.1046/j.1365-313x.1996.09020183.x · Cited by 287

Transgenic plant virus resistance mediated by untranslatable sense RNAs: expression, regulation, and fate of nonessential RNAs.

Smith, H. A., Swaney, S. L., Parks, T. D., Wernsman, E. A., & Dougherty, W. G. (1994) · The Plant Cell · doi:10.1105/tpc.6.10.1441 · Cited by 286

Induction of a Highly Specific Antiviral State in Transgenic Plants: Implications for Regulation of Gene Expression and Virus Resistance

Lindbo, J. A., Silva-Rosales, L., Proebsting, W. M., & Dougherty, W. G. (1993) · The Plant Cell · doi:10.2307/3869691 · Cited by 286

Expression of a truncated tomato polygalacturonase gene inhibits expression of the endogenous gene in transgenic plants

Smith, C. J. S., Watson, C. F., Bird, C. R., Ray, J., Schuch, W., & Grierson, D. (1990) · Molecular and General Genetics MGG · doi:10.1007/bf00262443 · Cited by 282

Epigenetic repeat-induced gene silencing (RIGS) inArabidopsis

Assaad, F. F., Tucker, K. L., & Signer, E. R. (1993) · Plant Molecular Biology · doi:10.1007/bf00028978 · Cited by 279

Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation.

Ingelbrecht, I., Van Houdt, H., Van Montagu, M., & Depicker, A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.22.10502 · Cited by 277

Cosuppression, Flower Color Patterns, and Metastable Gene Expression States

Jorgensen, R. A. (1995) · Science · doi:10.1126/science.268.5211.686 · Cited by 252

Differences in DNA‐methylation are associated with a paramutation phenomenon in transgenic petunia

Meyer, P., Heidmann, I., & Niedenhof, I. (1993) · The Plant Journal · doi:10.1046/j.1365-313x.1993.04010089.x · Cited by 217

Pathogen-Derived Resistance to a Potyvirus: Immune and Resistant Phenotypes in Transgenic Tobacco Expressing Altered Forms of a Potyvirus Coat Protein Nucleotide Sequence

Lindbo, J. A. (1992) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi-5-144 · Cited by 215

Distinct phenotypes generated by overexpression and suppression of S-adenosyl-L-methionine synthetase reveal developmental patterns of gene silencing in tobacco.

Boerjan, W., Bauw, G., Van Montagu, M., & Inzé, D. (1994) · The Plant Cell · doi:10.1105/tpc.6.10.1401 · Cited by 193

Identification of plant genetic loci involved in a posttranscriptional mechanism for meiotically reversible transgene silencing.

Dehio, C., & Schell, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.12.5538 · Cited by 178

Expression of an antisense viral gene in transgenic tobacco confers resistance to the DNA virus tomato golden mosaic virus.

Day, A. G., Bejarano, E. R., Buck, K. W., Burrell, M., & Lichtenstein, C. P. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.15.6721 · Cited by 167

Regulated inactivation of homologous gene expression in transgenic Nicotiana sylvestris plants containing a defense-related tobacco chitinase gene

Hart, C. M., Fischer, B., Neuhaus, J.-M., & Meins, F. (1992) · Molecular and General Genetics MGG · doi:10.1007/bf00279359 · Cited by 165

What makes an mRNA anti-sensi-itive?

Nellen, W., & Lichtenstein, C. P. (1993) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(93)90137-c · Cited by 150

Methylation induced premeiotically in Ascobolus: coextension with DNA repeat lengths and effect on transcript elongation.

Barry, C., Faugeron, G., & Rossignol, J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.10.4557 · Cited by 121

Co-suppression of nitrate reductase host genes and transgenes in transgenic tobacco plants

de Borne, F. D., Vincentz, M., Chupeau, Y., & Vaucheret, H. (1994) · Molecular and General Genetics MGG · doi:10.1007/bf00279570 · Cited by 108

Post-transcriptional cosuppression of beta-1,3-glucanase genes does not affect accumulation of transgene nuclear mRNA.

de Carvalho‐Niebel, F., Frendo, P., MONTAGU, M. V., & Cornelissen, M. (1995) · The Plant Cell · doi:10.1105/tpc.7.3.347 · Cited by 108

Control of mRNA stability in higher plants

Abler, M. L., & Green, P. J. (1996) · Plant Molecular Biology · doi:10.1007/bf00039377 · Cited by 98

A variety of epistatic interactions can occur between partially homologous transgene loci brought together by sexual crossing

Matzke, M. A., Neuhuber, F., & Matzke, A. J. M. (1993) · Molecular and General Genetics MGG · doi:10.1007/bf00277137 · Cited by 73

Inactivation of Repeated Genes — DNA-DNA Interaction?

Matzke, M. A., Matzke, A. J. M., & Scheid, O. M. (1994) · Springer eBooks · doi:10.1007/978-94-011-1094-5_12 · Cited by 61

Developmental Regulation of Co-suppression In Petunia hybrida

Flavell, R. B., O’Dell, M. R., Metzlaff, M., Bonhomme, S., & Cluster, P. D. (1995) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-79145-1_4 · Cited by 6

Role for a bidentate ribonuclease in the initiation step of RNA interference

Bernstein, E., Caudy, A. A., Hammond, S. M., & Hannon, G. J. (2001) · Nature · doi:10.1038/35053110 · Cited by 4,892

siRNA-mediated gene silencing in vitro and in vivo

Xia, H., Mao, Q., Paulson, H. L., & Davidson, B. L. (2002) · Nature Biotechnology · doi:10.1038/nbt739 · Cited by 873

Genetic Requirements for Inheritance of RNAi in C. elegans

Grishok, A., Tabara, H., & Mello, C. C. (2000) · Science · doi:10.1126/science.287.5462.2494 · Cited by 447

BAS1 : A gene regulating brassinosteroid levels and light responsiveness in Arabidopsis

Neff, M. M., Nguyen, S. M., Malancharuvil, E. J., Fujioka, S., Noguchi, T., Seto, H., Tsubuki, M., Honda, T., Takatsuto, S., Yoshida, S., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.15316 · Cited by 386

Plant viral suppressors of RNA silencing

Roth, B. (2004) · Virus Research · doi:10.1016/j.virusres.2004.01.020 · Cited by 329