Cited by 140Pancreatic function and diabetesNeuroendocrine Tumor Research AdvancesNeuropeptides and Animal Physiology

Monoamines in the pancreatic islets of the mouse: Subcellular localization of 5-hydroxytryptamine by electron microscopic autoradiography

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Ekholm, R., Ericson, L. E., Lundquist, I.·1971·Diabetologia

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Crossref · 10.1007/bf01219468

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  • Serotonin is synthesized within β-cells and stored with insulin in secretory granules.

    “it has been known for a long time that serotonin (5-hydroxytryptamine; 5-HT) is synthesized within β-cells and stored together with insulin in secretory granules [77,78]”

    From Expansion of β-cell mass in response to pregnancy (2010) · cites this paper as [77]

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Research works printed but not linked: 3

  1. Ekholm, R., Ericson, L.E.: Monoaminergic mech- anisms in the exocrine pancreas of the mouse studied with electron microscopic autoradiography. J. Ultra- struct. Res. in press (1971).
  2. ---Pettersson, B., Aim, G.: The two types of pancreatic A cells and their relation to the glucagon secretion. In: Brolin, S.E., Hellman, B., Knutson, F. (Eds.): The Structure and Metabolism of the Pan- ereatic Islets, pp. 117--130. London: Pergamon Press 1964.
  3. Pearse, A.G.E.: Common eytoehemical and ultra- structural characteristics of cells producing poly- peptide hormones (the APUD series) and their rele- vance to thyroid and ultimobranchial C cells and eMeitonin. Proc. roy. Soc. Lond. B. 170, 71--80 (1968).

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Authors
Ekholm, R., Ericson, L. E., & Lundquist, I.
Affiliations
Lund University (SE)
Venue
Diabetologia
Published
1971-10
Volume
7
Issue
5
Pages
339-348
ISSN
  • 0012-186X (ISSN-L)
  • 1432-0428
OpenAlex
W2913344694
Cited by
139
References
57
Citations by year
2026: 1 · 2025: 1 · 2024: 4 · 2023: 1 · 2022: 2 · 2021: 9 · 2020: 8 · 2019: 3 · 2017: 6 · 2016: 4 · 2015: 5 · 2014: 4 · 2013: 1 · 2012: 2
FWCI
10.36
Type
journal article
Language
en
Open access
Locations
  • Diabetologia (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
  • Health Sciences › Medicine › Epidemiology › Neuroendocrine Tumor Research Advances
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Keywords
monoamines, pancreatic islets, serotonin, 5-hydroxytryptophan, B cells, specific granules, monoamine oxidase inhibition, reserpine, neuroendocrine cells
MeSH terms
Animals, Autoradiography, Dopamine, Histocytochemistry, 5-Hydroxytryptophan, Islets of Langerhans, Microscopy, Electron, Monoamine Oxidase, Reserpine, Tritium, Mice

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