Effect of graded exercise on esophageal motility and gastroesophageal reflux in trained athletes
Abstract
We evaluated the effect of graded exercise on esophageal motility and gastroesophageal reflux. We studied eight trained cyclists using a catheter with three strain-gauge transducers connected to a solid-state datalogger and an ambulatory intraesophageal pH monitor. Each study lasted 4 hr during which subjects exercised on a stationary bike for 1 hr at 60% of peak O2 uptake (O2 max), 45 min at 75% of O2 max, and for 10 min at 90% of O2 max. Subjects rested 1 hr before exercise (control period) and for 30 min between exercise sessions. Studies were performed after an overnight fast and subjects received only intravenous infusion of 5% glucose solution during the study. Plasma concentrations of gastrin, motilin, glucagon, pancreatic polypeptide (PP), and vasoactive intestinal peptide (VIP) were determined at rest and before and after each exercise session. The duration, amplitude, and frequency of esophageal contractions declined with increasing exercise intensity, and the differences were significant (P < or = 0.05) for all three variables at 90% O2 max. The number of gastroesophageal reflux episodes and the duration of esophageal acid exposure were significantly (P < or = 0.05) increased during exercise at 90% O2 max. Plasma hormone concentrations showed no significant changes between rest and the various exercise sessions. Thus, exercise has profound effects on esophageal contractions and gastroesophageal reflux which are intensity dependent. These effects are not mediated by…
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The direct correlation between exercise and a decrease in intra-esophageal pH, as well as acid reflux disease and an increased risk of AF, has been shown in many observational studies in elite athletes.
“The direct correlation between exercise and a decrease in intra-esophageal pH, as well as acid reflux disease and an increased risk of AF, has been shown in many observational studies in elite athletes [61,62,63,64].”
From Atrial Fibrillation in Elite Athletes: A Comprehensive Review of the Literature (2024) · cites this paper as [62]
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- Authors
- Soffer, E. E., Merchant, R. K., Duethman, G., Launspach, J., Gisolfi, C., & Adrian, T. E.
- Affiliations
- University of Iowa (US)
- Creighton University (US)
- Venue
- Digestive Diseases and Sciences
- Published
- 1993-02
- Volume
- 38
- Issue
- 2
- Pages
- 220-224
- ISSN
- 0163-2116 (ISSN-L)
- 1573-2568
- OpenAlex
- W2087522359
- Cited by
- 74
- References
- 31
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 1 · 2020: 1 · 2017: 2 · 2016: 3 · 2015: 3 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 3.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Digestive Diseases and Sciences (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Center for Research Resources
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- graded exercise, esophageal motility, gastroesophageal reflux, trained cyclists, exercise intensity, esophageal contractions, gastrin, motilin, glucagon, pancreatic polypeptide, vasoactive intestinal peptide
- MeSH terms
- Adult, Analysis of Variance, Bicycling, Esophagus, Exercise Test, Gastrins, Gastroesophageal Reflux, Glucagon, Humans, Hydrogen-Ion Concentration, Male, Manometry, Motilin, Pancreatic Polypeptide, Peristalsis, Reference Values, Vasoactive Intestinal Peptide, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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