SOCS proteins in regulation of receptor tyrosine kinase signaling
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SOCS negatively regulates JAK-STAT signaling.
“SOCS is characterized by possessing a central Src homology 2 (SH2) structural domain and a carbon-terminal SOCS box that negatively regulates JAK-STAT signaling [54].”
From Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression (2022) · cites this paper as [54]
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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
Rui, L., Yuan, M., Frantz, D., Shoelson, S., & White, M. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c200444200 · Cited by 904 · see citing works
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Emanuelli, M., Carnevali, F., Saccucci, F., Pierella, F., Amici, A., Raffaelli, N., & Magni, G. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m008700200 · Cited by 189 · see citing works
Mottok, A., Renné, C., Seifert, M., Oppermann, E., Bechstein, W., Hansmann, M.-L., Küppers, R., & Bräuninger, A. (2009) · Blood · doi:10.1182/blood-2009-06-225839 · Cited by 124 · see citing works
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Neuron secrete exosomes containing miR-9-5p to promote polarization of M1 microglia in depression
Xian, X., Cai, L.-L., Li, Y., Wang, R.-C., Xu, Y.-H., Chen, Y.-J., Xie, Y.-H., Zhu, X.-L., & Li, Y.-F. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01332-w · Cited by 169 · see citing works
- Authors
- Kazi, J. U., Kabir, N. N., Flores-Morales, A., & Rönnstrand, L.
- Venue
- Cellular and Molecular Life Sciences
- Published
- 2014-04-05
- Volume
- 71
- Issue
- 17
- Pages
- 3297-3310
- ISSN
- 1420-682X
- 1420-9071
- Cited by
- 92
- References
- 4
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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